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In this study we use Affinity Purification coupled with Mass Spectrometry (AP-MS) to test the effect of HMR overexpression (Hmr.over) or mutation (Hmr.dC and Hmr.2) on the interactome of HMR and in relation to the Speciation Core Complex (SCC). All affinity purifications were performed with a FLAG a...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2021-08-11 | PXD023193 | Pride
Cupriavidus sp. HMR-1 Genome sequencing and assembly
In this study we described the protein-protein interaction network of the Drosophila Speciation Core Complex by analysing the interactome of its subunit: HMR, LHR, NLP, BOH1 (CG33213), BOH2 (CG4788) and HP1a. For this purpose we performed Affinity Purification coupled with Mass Spectrometry (AP-MS) ...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2021-08-11 | PXD023188 | Pride
The hemera (hmr) mutant was identified as the first photomorphogenetic mutant with the combination of long hypocotyl and albino phenotypes in the light. Phytochrome-Interacting bHLH transcription Factors (PIFs), which are repressors of photomorphogenesis accumulate in darkness and are degraded in th...
ORGANISM(S): Arabidopsis thaliana 
Hybrid incompatibility between Drosophila melanogaster and D. simulans is caused by a lethal interaction of the proteins encoded by the Hmr and Lhr genes. In D. melanogaster the loss of HMR results in mitotic defects, an increase in transcription of transposable elements and a deregulation of hetero...
ORGANISM(S): Drosophila melanogaster 
2017-01-31 | GSE86106 | GEO
Nucleosome profiles in strains with different numbers of nucleosomes at HML and HMR
Genome-wide ChIP-Seq profiling of a wild-type and a C-terminally truncated mutant of HMR
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