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The purpose of this experiment was to compare differences in Alu-exon inclusion in cells depleted of hnRNPC, Upf1, or both.
ORGANISM(S): Homo sapiens 
The purpose of this experiment was to compare differences in gene expression in cytoplasmic and nuclear RNA of cells depleted of hnRNPC.
ORGANISM(S): Homo sapiens 
Cardiac pathologies are characterized by intense remodeling of the extracellular matrix (ECM) that eventually leads to heart failure. Cardiomyocytes respond to the ensuing biomechanical stress by re-expressing fetal contractile proteins via transcriptional and post-transcriptional processes, like al...
ORGANISM(S): Homo sapiens (Human) 
2026-07-06 | PXD020663 | Pride
Differentially expressed genes in HNRNPC knockdown MHCC97H cells
Transcriptome profiling of cells depleted of hnRNPC, Upf1, or co-depleted of hnRNPC and Upf1.
To define and compare the interactomes of the RNA binding protein HNRNPC in poorly vs. efficiently metastatic breast adenocarcinoma cells, we carried out immunoprecipitation of endogenous HNRNPC from parental MDA-MB231 cells vs. its highly metastatic isogenic derivate, the MDA-MB231-LM2 cells. We us...
ORGANISM(S): Homo sapiens (Human) 
2023-02-19 | PXD029560 | Pride
HNRNPC RIP-Seq and RNA-Sequence Analysis of si-LY6E-DT and si-HNRNPC in 231 cells
We performed RNA-seq experiments on two replicate samples from each HNRNPC knockdown (KD1 and KD2) As well as from control HeLa cells. Library preparation was preformed according to mRNA Sequencing Sample Preparation Guide (Illumina, Part # 1004898 REV. D). Reagents were taken from the Illumina samp...
ORGANISM(S): Homo sapiens 
The role of HNRNPC-PABPC4 on polyA site selection
hNRNPC iCLIP
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