Sort   by:  
 Page size 
MetabolomicsSerum LC-MS metabolomics profiling during musk secretion in captive forest musk deer (Moschus berezovskii)
This study investigates serum metabolomic changes associated with musk secretion in captive male forest musk deer (Moschus berezovskii). Paired serum samples were collected before secretion and during secretion and analyzed using LC-MS in both positive and negative ion modes. The study includes biol...
2026-04-23 | MTBLS14280 | MetaboLights
ProteomicsBiosynthesis and secretion of the microbial sulfated peptide RaxX and binding to the rice XA21 immune receptor
The rice immune receptor XA21 is activated by the sulfated microbial peptide RaxX (required for activation of XA21-mediated immunity X) produced by Xanthomonas oryzae pv. oryzae (Xoo). Mutational studies and targeted proteomics revealed that RaxX is processed and secreted by the protease/transporter...
ORGANISM(S): Xanthomonas Oryzae Pv. Oryzae 
PXD013389 | panorama
MetabolomicsProteomic analysis validates previous findings on wounding-responsive plant hormone signaling and primary metabolism contributing to the biosynthesis of secondary metabolites based on metabolomic analysis in harvested broccoli (Brassica oleracea L. var. italica)
The plant wound-response is a complex process that generates physiological modifications for protecting the wounded tissue. In this study, tandem mass tag (TMT)-based quantitative proteomic analysis was performed to clarify the comprehensive molecular mechanism for the wound-response of broccoli subj...
2021-05-19 | MTBLS2317 | MetaboLights
TranscriptomicsTranscription profiling of Drosophila Hr39 mutant females reveals the sf1-related nuclear hormone receptor hr39 regulates Drosophila female reproductive tract development and function
The vertebrate nuclear hormone receptor steroidogenic factor 1 (SF1; NR5A1) controls reproductive development and regulates the transcription of steroid-modifying cytochrome P450 genes. We find that the SF1-related Drosophila nuclear hormone receptor HR39 is also essential for sexual development. In...
ORGANISM(S): Drosophila melanogaster 
2008-06-11 | E-GEOD-10264 | biostudies-arrayexpress
ProteomicsCoordinate control of endoplasmic reticulum chaperone biosynthesis and peptide hormone secretion revealed by a β-cell model of Prader-Willi syndrome
Prader-Willi syndrome (PWS) is a multisystem disorder caused by loss of expression of a cluster of paternally-expressed, imprinted genes. Neonatal failure to thrive is followed by childhood-onset hyperphagia, obesity, neurobehavioral abnormalities, and hormonal deficits. Prior evidence from a mouse ...
ORGANISM(S): Rattus norvegicus (Rat) 
2023-04-11 | PXD037875 | Pride
Crispr/cas9  genomic imprinting  hormone secretion  metabolic disease  pancreatic islet 
ProteomicsCoordinate control of endoplasmic reticulum chaperone biosynthesis and peptide hormone secretion revealed by a β-cell model of Prader-Willi syndrome
Prader-Willi syndrome (PWS) is a multisystem disorder caused by loss of expression of a cluster of paternally-expressed, imprinted genes. Neonatal failure to thrive is followed by childhood-onset hyperphagia, obesity, neurobehavioral abnormalities, and hormonal deficits. Prior evidence from a mouse ...
ORGANISM(S): Rattus norvegicus (Rat) 
2023-04-11 | PXD037874 | Pride
Crispr/cas9  genomic imprinting  hormone secretion  metabolic disease  pancreatic islet 
ProteomicsCoordinate control of endoplasmic reticulum chaperone biosynthesis and peptide hormone secretion revealed by a β-cell model of Prader-Willi syndrome
Prader-Willi syndrome (PWS) is a multisystem disorder caused by loss of expression of a cluster of paternally-expressed, imprinted genes. Neonatal failure to thrive is followed by childhood-onset hyperphagia, obesity, neurobehavioral abnormalities, and hormonal deficits. Prior evidence from a mouse ...
ORGANISM(S): Rattus norvegicus (Rat) 
2023-04-11 | PXD034471 | Pride
Crispr/cas9  genomic imprinting  hormone secretion  metabolic disease  pancreatic islet 
TranscriptomicsComparison of gene expression in rice leaves inoculated with a virulent strain of Xanthomonas oryzae and its mutant deficient in typeIII secretion system.
Gene expression profiles in rice leaves near the inoculated site of Xanthomonas oryzae and its typeIII secretion mutant were examined. Rice plants (cv Nippnbare, 42 days old) were clip-inoculated with a virulent strain of Xanthomonas oryzae and its △hrcV mutant. At each time points, leaf segments w...
ORGANISM(S): Oryza sativa 
2015-04-01 | E-GEOD-63047 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human peripheral blood mononuclear cells in vitro from CIS patients after Interferon beta-1a treatment
IFNβ, an effective therapy against relapsing-remitting (RR) multiple sclerosis (MS) is naturally secreted during the innate immune response against viral pathogens. The objective of this study was to characterize the immunomodulatory mechanisms of IFNβ targeting innate immune response and their effe...
ORGANISM(S): Homo sapiens 
2009-01-17 | E-GEOD-14386 | biostudies-arrayexpress
TranscriptomicsSex-specific early growth hormone response genes in rat liver (Rattus norvegicus)
A series of two color gene expression profiles obtained using Agilent 44K expression microarrays was used to examine sex-dependent and growth hormone-dependent differences in gene expression in rat liver. This series is comprised of pools of RNA prepared from untreated male and female rat liver, hy...
ORGANISM(S): Rattus norvegicus 
2008-05-24 | E-GEOD-11529 | biostudies-arrayexpress
Sort   by:  
 Page size