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TranscriptomicsHost and non-host pathogens elicit different jasmonate/ethylene responses in Arabidopsis
Arabidopsis does not support the growth and asexual reproduction of the barley pathogen, Blumeria graminis f. sp. hordei Bgh). A majority of germlings fail to penetrate the epidermal cell wall and papillae. To gain additional insight into this interaction, we determined whether the salicylic acid (S...
ORGANISM(S): Arabidopsis thaliana 
2005-08-26 | E-GEOD-3199 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis eds1 mutant and NahG transgenics infection penetration success by the barley powdery mildew Blumeria graminis f. sp. hordei Bgh
Arabidopsis does not support the growth and asexual reproduction of the barley pathogen, Blumeria graminis f. sp. hordei Bgh). A majority of germlings fail to penetrate the epidermal cell wall and papillae. To gain additional insight into this interaction, we determined whether the salicylic acid (S...
ORGANISM(S): Arabidopsis thaliana 
2005-08-23 | E-SMDB-2432 | biostudies-arrayexpress
UnknownThe cytoskeleton in cell-autonomous immunity: structural determinants of host defence.
Not available
S-EPMC4869833 | biostudies-literature
MetabolomicsMetabolic profiling of rheumatoid arthritis neutrophils reveals altered energy metabolism that is not affected by JAK inhibition
Neutrophils play a key role in the pathophysiology of rheumatoid arthritis (RA) where release of ROS and proteases directly causes damage to joints and tissues. Neutrophil function is directly affected by Janus Kinase (JAK) inhibitor drugs, including tofacitinib and baricitinib, which are clinically...
2023-07-11 | MTBLS4766 | MetaboLights
TranscriptomicsTrancription profiling of the hepatoma cell line Huh7 infected with the Hepatitis C Virus
Hepatitis C Virus is a leading cause of chronic liver disease. The identification and characterisation of key host cellular factors that play a role in the HCV replication cycle is important for the understanding of disease pathogenesis and the identification of novel anti-viral therapeutic targets....
ORGANISM(S): Homo sapiens 
2010-05-27 | E-GEOD-20948 | biostudies-arrayexpress
TranscriptomicsFunctional genomics identifies type I interferon pathway as central for host defense against Candida albicans
Candida albicans is the most common human fungal pathogen causing mucosal and systemic infections. However, human antifungal immunity remains poorly defined. By integrating transcriptional analysis and functional genomics we identified Candida-specific host defense mechanisms in humans. Candida indu...
ORGANISM(S): Homo sapiens 
2012-12-01 | E-GEOD-42630 | biostudies-arrayexpress
UnknownHost defence peptide plectasin targets bacterial cell wall precursor lipid II by a calcium-sensitive supramolecular mechanism.
Not available
S-EPMC11222147 | biostudies-literature
GenomicsZone-specific hepatocytes orchestrate the early onset of host defence mechanisms during Staphylococcus aureus bloodstream infection
Zone-specific hepatocytes orchestrate the early onset of host defence mechanisms during Staphylococcus aureus bloodstream infection
PRJNA1372145 | ENA
UnknownThe Xanthomonas campestris type III effector XopJ targets the host cell proteasome to suppress salicylic-acid mediated plant defence.
Not available
S-EPMC3681735 | biostudies-literature
ProteomicsHost-defence peptides caerin 1.1 and 1.9 stimulate TNF-alpha-dependent apoptosis in human cervical cancer HeLa cells
TNFα pathway has been recognised as one of the most important signalling pathways characterising molecules with anti-cancer activity, due to it closely relates to cell survival as well as apoptosis. Isolated from the glandular secretion of Australian tree frogs, the genus Litoria, host-defence caeri...
ORGANISM(S): Homo sapiens (Human) 
2020-08-27 | PXD015975 | Pride
Proteomics Hela cell Tmt labelling Tnfα signalling pathway Caerin peptide Apoptosis Confocal microscopy Western blot 
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