Sort   by:  
 Page size 
TranscriptomicsHP1a recruitment to promoters is independent of H3K9 methylation in Drosophila melanogaster
Heterochromatin protein 1 (HP1) proteins are important regulators of heterochromatin mediated gene silencing and chromosome structure and it is well known as the reader of the heterochromatin mark methylation of histone H3 lysine 9 (H3K9me). In Drosophila three different histone lysine methyl transf...
ORGANISM(S): Drosophila melanogaster 
2012-12-21 | E-GEOD-38366 | biostudies-arrayexpress
GenomicsHeterochromatin remodeling by CDK12 contributes to learning in Drosophila
We describe the epigenetic profiling of the H3K9me2 and HP1a in Drosophila third instar larvae before and after CDK12 depletion by RNA interference (RNAi). Here we show that CDK12 regulates heterochromatin dynamics in Drosophila chromosomes. Depletion of CDK12 induces the increased HP1a and H3K9me2 ...
ORGANISM(S): Drosophila melanogaster 
2015-11-02 | E-GEOD-63011 | biostudies-arrayexpress
ProteomicsDrosophila HP1a IP-MS - The composition and organization of Drosophila heterochromatin are heterogeneous and dynamic
Heterochromatin is enriched for characteristic epigenetic factors, including Heterochromatin Protein 1a (HP1a) and is essential for many organismal functions. However, how this nuclear domain is organized and functions is unclear. We extensively investigated heterochromatin protein compostion by bio...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2016-08-18 | PXD003780 | Pride
Heterochromatin protein 1a Drosophila melanogaster 
TranscriptomicsHP1a, Su(var)3-9, SETDB1 and POF stimulate or repress gene expression depending on genomic position, gene length and expression pattern in Drosophila melanogaster
Heterochromatin protein 1a (HP1a) is a chromatin associated protein that has been well studied in many model organisms, such as Drosophila, where it is a determining factor for classical heterochromatin. HP1a is associated with the two histone methyltransferases SETDB1 and Su(var)3-9, which mediate ...
ORGANISM(S): Drosophila melanogaster 
2013-04-05 | E-GEOD-43478 | biostudies-arrayexpress
TranscriptomicsRNA expression in Drosophila melanogaster mutants lacking HP1a
mRNA expression levels were determined by NGS for wildtype larvae as well as for larvae lacking HP1a [Su(var)205^04/Su(var)205^05 transheterozygotes]. RNA samples from wildtype (OR) and HP1a mutant third instar larvae were examined, using duplicate biological samples and Illumina NGS.
ORGANISM(S): Drosophila melanogaster 
2012-09-01 | E-GEOD-39083 | biostudies-arrayexpress
TranscriptomicsHeterochromatin-associated interactions of Drosophila HP1 with dADD1, HIPP1, and repetitive RNAs
We report chromatin-associated protein and RNA interactions of HP1a, indentified by BioTAP-XL mass spectrometry and sequencing. We identify an extensive list of both known and novel HP1a-interacting proteins from Drosophila S2 cells and from whole organisms across embryonic, larval and adult stages....
ORGANISM(S): Drosophila melanogaster 
2014-07-03 | E-GEOD-56101 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of human centromeric protein A, histone3 K4 and K9 modifications, HP1a and HP1g
Chromatin Immunoprecipitation of centromeric protein A, histone3 K4 and K9 modifications, HP1a and HP1g
ORGANISM(S): Homo sapiens 
2010-02-27 | E-TABM-705 | biostudies-arrayexpress
TranscriptomicsHP1a wa184.S2
modENCODE_submission_2668 This submission comes from a modENCODE project of Gary Karpen. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We aim to determe the locations of 125 chromosomal proteins and histone modifications across the Drosophila melanogaster geno...
ORGANISM(S): Drosophila melanogaster 
2010-08-10 | E-GEOD-23483 | biostudies-arrayexpress
TranscriptomicsGene expression signatures in Tif1b, Hp1a or Hp1g knockdown hematopoietic progenitors
Gene expression analyses of Tif1b, Hp1a or Hp1g knockdown hematopoietic progenitors. Growth of hematopoietic stem cells (HSCs) are significantly impaired upon knockdown of Hp1a and Hp1g. Results provide insight into the role of these factors in hematopoiesis. HSCs (CD34- c-Kit+ Sca1+ Lineage- ) we...
ORGANISM(S): Mus musculus 
2014-08-01 | E-GEOD-48897 | biostudies-arrayexpress
TranscriptomicsHP1a wa184.BG3
modENCODE_submission_4126 This submission comes from a modENCODE project of Gary Karpen. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: We aim to determine the locations of 125 chromosomal proteins across the Drosophila melanogaster genome. The proteins under s...
ORGANISM(S): Drosophila melanogaster 
2013-02-22 | E-GEOD-44515 | biostudies-arrayexpress
Sort   by:  
 Page size