humoral immunity

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Unknown (4878)
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Models (3)
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Organisms

Mus musculus (197)
Homo sapiens (116)
Aerococcus urinae NBRC 15544 = CCUG 36881 (30)
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Rubella virus vaccine strain RA27/3 (1)
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Spirometra erinaceieuropaei (1)
Urechis unicinctus (1)

Organisms

Mus musculus (167)
Homo sapiens (83)
Macaca mulatta (9)
Drosophila melanogaster (3)
Sus scrofa (2)
human gut metagenome (2)
Hemiptera (1)
Plasmodium falciparum 3D7 (1)
Cricetulus griseus (1)
Macaca fascicularis (1)
Influenza A virus (1)
Gryllus bimaculatus (1)
Antheraea pernyi (1)
Chlorocebus sabaeus (1)
Salmo salar (1)
Felis catus (1)
Canis lupus familiaris (1)
mouse gut metagenome (1)
Plasmodium falciparum (1)
Gallus gallus (1)

Repository

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Tissue

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Disease

Wounds and Injuries (2)
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Bone marrow (1)
Human cytomegalovirus infection (1)
Influenza (1)
Malignant neoplasm of ovary (1)
Viral infectious disease (1)

Technology Type

Mass Spectrometry (31)
Shotgun proteomics (16)
Gel-based experiment (6)
Bottom-up proteomics (5)
Mass spectrometry assay (4)
Mass spectrometry (3)
ESI (1)
Affinity proteomics (1)
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Data-dependent acquisition (1)
Data-independent acquisition (1)
SWATH MS (1)

Instrument Platform

Illumina NovaSeq 6000 (6)
Liquid Chromatography MS - negative - reverse phase (4)
Illumina HiSeq 2000 (3)
Liquid Chromatography MS - positive - reverse phase (3)
Illumina NovaSeq X (2)
NextSeq 500 (2)
Q Exactive Plus (2)
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Agilent G2565BA Microarray Scanner System (Agilent Technologies, Santa Clara, CA) (1)
Tecan HS4800 hybridization station (Tecan, Vienna, Austria) (1)
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Liquid Chromatography MS - (1)

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2011 (8)
2010 (8)
2013 (7)
2008 (7)
2015 (3)
2007 (3)
2009 (1)
2006 (1)
2005 (1)

CHEBI ID

CHEBI:16856 (2)
CHEBI:15891 (2)
CHEBI:17895 (2)
CHEBI:17295 (2)
CHEBI:136162 (1)
CHEBI:194274 (1)
CHEBI:182120 (1)
CHEBI:194273 (1)
CHEBI:113535 (1)
CHEBI:134075 (1)
CHEBI:51686 (1)
CHEBI:74970 (1)
CHEBI:136123 (1)
CHEBI:183014 (1)
CHEBI:176766 (1)
CHEBI:136378 (1)
CHEBI:190528 (1)
CHEBI:134589 (1)
CHEBI:194275 (1)
CHEBI:183780 (1)
CHEBI:167820 (1)
CHEBI:89690 (1)
CHEBI:134595 (1)
CHEBI:64243 (1)
CHEBI:194278 (1)
CHEBI:7989 (1)
CHEBI:192581 (1)
CHEBI:183461 (1)
CHEBI:194270 (1)
CHEBI:6919 (1)

Metabolite Name

Capric acid (3)
Undecanedioic acid (3)
N-Acetylneuraminic acid (3)
Taurine (3)
10-Hydroxydecanoic acid (3)
Pseudouridine (3)
2-Ketohexanoic acid (2)
Dihydroroseoside (2)
Fucose 1-phosphate (2)
Actarit (2)
Galactaric acid (2)
Gallocatechin (2)
UDP-N-acetylglucosamine (2)
Inosinic acid (2)
Pelargonic acid (2)
Pyrrole-2-carboxylic acid (2)
N-Acetylgalactosamine (2)
N-Lactoylphenylalanine (2)
Gallic acid (2)
Ethylmalonic acid (2)
N-Tigloylglycine (2)
2,6-Dihydroxybenzoic acid (2)
Pentadecanoic acid (2)
Succinyladenosine (2)
Thr-Leu (2)
2'-Deoxyuridine (2)
Sulfamethazine (2)
L-Aspartic acid (2)
Hydroxyphenyllactic acid (2)
Citrulline (2)

First Public Date

2026 (82)
2024 (56)
2025 (42)
2023 (36)
2020 (26)
2021 (23)
2022 (22)
2014 (19)
2018 (13)
2016 (12)
2019 (11)
2017 (7)
2015 (2)
2013 (2)

Modelling Approach

Agent-based model (1)

Study status

Completed (1)

Lab affiliation

Department of Pharmaceutics, School of Pharmaceutical Sciences of Wenzhou Medical University (2)
Biomolecular Mass Spectrometry and Proteomics Utrecht University (1)
Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge, CB2 0XY, UK (1)
Core Facility Proteomics, Department of Clinical Chemistry, University Medical Center Goettingen, Germany (1)
Department of Biology, Maynooth University, Co. Kildare, Ireland. (1)
Department of Biology, Maynooth University, Co. Kildare, Ireland. Phone: + 353 - 1- 708 3859. Fax: + 353 - 1- 708 3845. (1)
Department of Clinical and Experimental Medicine, Cell biology, Faculty of Health Science Linköping University, SE-581 83 Linköping, Sweden (1)
Department of Entomology and Plant Pathology, 127 Noble Research Center, Oklahoma State University, Stillwater, Oklahoma, USA, 74078 (1)
Department of Immunology, Weizmann Institute of Science, Rehovot, Israel (1)
Department of Microbiology and Immunology, University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne 3000, Australia (1)
Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute Jena (Leibniz-HKI) (1)
Division of Chemistry I, Department of Medical Biochemistry & Biophysics, Karolinska Institutet (1)
Evolution and Specificity of Multitrophic Interactions (ESIM) Sophia Agrobiotech Institute (ISA) INRAE, Université Côte d’Azur, CNRS 06903 Sophia Antipolis Cedex France (1)
Faculty of Chemistry, Biotechnology and Food Science Norwegian University of Life Sciences Post Office Box 5003 1432, Ås Norway (1)
Immunology, Moffitt Cancer Center, Tampa, FL (1)
Infectious Diseases and Immunity in Global Health Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada (1)
Institute of Parasitology, Biology Centre of the Czech Academy of Sciences, Branisovska 1160/31, 37005 Ceske Budejovice, Czech Republic (1)
Laboratoire de Spectrométrie de Masse BioOrganique, Analytical Science department, IPHC, CNRS, Strasbourg University, UMR7178, Stasbourg, France (1)
Medical Mycology Laboratory, Department of Biology, Maynooth University, Co. Kildare, Ireland. (1)
National Center for Microbiology, Instituto de Salud Carlos III. Majadahonda, Madrid, Spain (1)
No.139 Renmin Middle Road, Changsha, 410011, Hunan, PR China (1)
Regents Professor Department of Entomology & Plant Pathology Oklahoma State University, Stillwater, OK 74078 Telephone: 405-744-9400 (1)
SaBio. Instituto de Investigación en Recursos Cinegéticos IREC-CSIC-UCLM-JCCM, Ronda de Toledo s/n, 13005 Ciudad Real, Spain. (1)
Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Science (1)
Technical University Munich, Faculty of Medicine, Institute of Virology, Viral Immunopathology, Schneckenburger Str. 8, D-81675 Munich, Germany (lab head) (1)
University Hospital Schleswig-Holstein, Campus Lübeck, Department of Surgery (1)
University of Florida, Gainesville, FL. USA (1)
University of Southern Denmark, Faculty of Science, Departments of Biochemistry and Molecular Biology (1)
Villanova University, USA (1)

Keyword

Neutrophil phagocytosis (1)
Neutrophil adhesivity (1)
Glutamine (1)
Omega 3 fatty acids (1)
Nutrition (1)

IsPrivate

False (2)

Submitter Keywords

Immuno-oncology (1)

Classification

protozoa (2)
viruses (1)

Study type

Transcription profiling by array (37)
RNA-seq of coding RNA (14)
ChIP-seq (6)
RNA-seq of coding RNA from single cells (6)
Human - One-color microarray (2)
Proteomic profiling by array (2)
Transcription profiling by SAGE (1)
One-color microarray (1)
Spatial transcriptomics by high-throughput sequencing (1)
MicroRNA profiling by array (1)
Interventional (1)

Release Date

2022 (830)
2023 (638)
2021 (592)
2025 (461)
2024 (410)
2020 (332)
2018 (237)
2019 (228)
2017 (205)
2016 (173)
2015 (147)
2014 (132)
2013 (97)
2012 (88)
2026 (66)
2011 (63)
2010 (51)
2009 (51)
2008 (34)
2006 (26)
2007 (22)
2005 (16)
2002 (10)
2004 (9)
2001 (9)
2003 (8)
1998 (7)
2000 (5)
1999 (3)

Location

Turkey (1)

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Mitochondrial respiration in B lymphocytes is essential for humoral immunity by controlling flux of the TCA cycle

To elucidate the function of oxidative phosphorylation (OxPhos) during B-cell differentiation we employ CD23Cre-driven expression of the dominant-negative K320E mutant of the mitochondrial helicase Twinkle (DNT). DNT-expression depletes mitochondrial DNA during B cell maturation, reduces the abun...

2026-08-21 | MTBLS4647 | MetaboLights

Nano-formulated bisphosphonate adjuvants simultaneously induce humoral and cellular immunity

Adjuvant is an important component of vaccines However, given the limitation of existing adjuvants in variety and mechanism, developing a unique and effective adjuvant is urgently needed for clinal applications. Recent studies have implicated that the mevalonate pathway plays an essential role in va...

2026-03-03 | MTBLS11696 | MetaboLights

Mitochondrial respiration in B lymphocytes is essential for humoral immunity by controlling flux of the TCA cycle

Not available

ORGANISM(S): Mus musculus

ST002140 | MetabolomicsWorkbench

Gut microbiota-derived butyrate primes systemic immunity in honeybees by mediating lipid metabolic reprogramming

The gut microbiota plays a crucial role in insect immune priming, inducing memory-like response that functionally resembles adaptive immunity confined to vertebrates. While gut microbiota mediates systemic immune activation in insect hemolymph, the mechanisms underlying remote immunoregulation re...

2025-10-07 | MTBLS13098 | MetaboLights

Metabolic control of Tfh and humoral immunity by phosphatidylethanolamine

PRJNA613290 | ENA

CD40-induced humoral immunity

PRJNA1441975 | ENA

Stearoyl-CoA desaturase mediated monounsaturated fatty acid availability supports humoral immunity

PRJNA681897 | ENA

Early gene expression after COVID-19 mRNA (BNT162b2) vaccination that is associated with spike-specific T cell responses

This study investigates the post-vaccination gene expression associated with T cell response and why humoral immunity does not inform cellular responses post-vaccination. The experiment is the transcriptional profiling of peripheral blood mononuclear cells (PBMCs) from 21/27 subjects collected at da...

ORGANISM(S): Homo sapiens

2026-04-21 | E-MTAB-15195 | biostudies-arrayexpress

Venous plexus-associated lymphoid hubs support meningeal humoral immunity

PRJNA1064095 | ENA

IL-6-mediated endothelial injury impairs anti-viral humoral immunity

PRJNA1058435 | ENA

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