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Due to marketing recommendations, white wines are often bottled in flint glass to improve aesthetics and showcase wine color. Although this practice is known to cause a wine fault, the influence of light on the fruity and flowery aromatic profile of wine is unknown. The aim of this study was to i...

2022-07-06 | MTBLS3201 | MetaboLights

Regional structure of the intestinal epithelium is critical for its function and is associated with the risk of specific gut diseases. However, how regionalization is established and how it influences disease susceptibility remains poorly understood. Here, we investigated the role of the gut micr...

2026-03-27 | MTBLS12063 | MetaboLights

Real-time breath analysis using secondary electrospray ionization coupled with high-resolution mass spectrometry is a fast and noninvasive method to access the metabolic state of a person. However, it lacks the ability to unequivocally assign mass spectral features to compounds due to the absence...

2023-01-26 | MTBLS6760 | MetaboLights

Human embryonic stem cells (hESCs) can self-renew infinitely or differentiate into the 3 germ layer lineages in vitro with certain cues, holding great promise to model early human embryo development ex vivo. It is wildly accepted that hESCs take advantage of both glycolysis and ...

2022-03-03 | MTBLS4223 | MetaboLights
This experiment investigates the rhizosphere metabolome of two subtropical tree species (Pinus massoniana and Liquidambar formosana) grown in pure and mixed forest stands. Rhizosphere soil samples were collected from each forest type, and root-associated metabolites were extracted and analyzed using...
2026-08-02 | MTBLS15227 | MetaboLights
Induced pluripotent stem cell (iPSC)-derived cortical neurons present a powerful new model of neurological disease. Previous work has established that differentiation protocols produce cortical neurons but little has been done to characterise these at cellular resolution. In particular, it is unclea...
ORGANISM(S): Homo sapiens 
Regional identity of human neural stem cells determinesoncogenic responses to histone 1H3.3 mutants
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD021270 | Pride
Areas and layers of the cerebral cortex are specified by genetic programs that are initiated in progenitor cells and then, implemented in postmitotic neurons. Here, we report that Tbr1, a transcription factor expressed in postmitotic projection neurons, exerts positive and negative control over both...
ORGANISM(S): Mus musculus 
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