Sort   by:  
 Page size 
MetabolomicsOrganotypic microfluidic breast cancer model reveals starvation-induced spatial-temporal metabolic adaptations
BACKGROUND: Ductal carcinoma in situ (DCIS) is the earliest stage of breast cancer. During DCIS, tumor cells remain inside the mammary duct, growing under a microenvironment characterized by hypoxia, nutrient starvation, and waste product accumulation; this harsh microenvironment promotes genomic in...
2019-02-08 | MTBLS669 | MetaboLights
TranscriptomicsDifferentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer
This SuperSeries is composed of the following subset Series: GSE41194: Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer (Group 1) GSE41196: Differentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive...
ORGANISM(S): Homo sapiens 
2012-09-29 | E-GEOD-41228 | biostudies-arrayexpress
TranscriptomicsGene Expression and Comparative Genomic Hybridization of Ductal Carcinoma In Situ of the Breast
Background The dramatic increase in incidence of ductal carcinoma in situ (DCIS) associated with mammographic screening for breast cancer has given emphasis to the challenges of managing this important clinical entity. Unlike invasive breast cancer, there is no established histopathologic grading sy...
ORGANISM(S): Homo sapiens 
2008-11-24 | E-GEOD-7882 | biostudies-arrayexpress
MetabolomicsSpatial multi-omics inference of diabetes mellitus triggering pancreatic cancer growth through cholesterol-induced neutrophil extracellular traps

Spatial multi-omics inference of diabetes mellitus triggering pancreatic cancer growth through cholesterol-induced neutrophil extracellular traps

2025-11-26 | MTBLS12782 | MetaboLights
TranscriptomicsSpatial transcriptomic analyses of triple negative and luminal A breast ductal carcinoma in situ
This experiment includes GeoMx spatial transcriptomic analyses of FFPE tissue from breast ductal carcinoma in situ lesions from 16 patients. All lesions were subject to ER, PR, HER2 and Ki67 immunohistochemistry and assigned a molecular subtype. The main aim was to compare DCIS of the two subtypes T...
ORGANISM(S): Homo sapiens 
2026-06-26 | E-MTAB-16918 | biostudies-arrayexpress
MetabolomicsMetabolomic Profiling of Personalized Cancer Therapy Responses in Organoid Chips

This study investigates metabolomic changes associated with personalized cancer therapy responses in patient-derived organoid chips containing a reconstructed tumor microenvironment. The dataset includes de-identified sample metadata, raw mass spectrometry files, processed metabolite abundance ma...

2026-08-06 | MTBLS15195 | MetaboLights
TranscriptomicsDNA methylation profiling of ductal carcinoma in situ (DCIS)
Methylated genomic fragments from tumor DNA and matching normal control were enriched with the methylated-CpG island recovery assay (MIRA); amplified, labeled and hybridized on Agilent CpG island tiling oligo arrays. MIRA enriched samples from tumor were labeled with Cy5 while MIRA enriched DNA samp...
ORGANISM(S): Homo sapiens 
2010-05-05 | E-GEOD-14865 | biostudies-arrayexpress
TranscriptomicsIdentification of circulating lncRNAs associated with gallbladder cancer risk by tissue-based preselection, cis-eQTL validation, and analysis of association with genotype-based expression
Long non-coding RNAs (lncRNAs) play key roles in cell processes and are good candidates for cancer risk prediction. Few studies have investigated the association between individual genotypes and lncRNA expression. Here we integrate three separate datasets with information on lncRNA expression only, ...
ORGANISM(S): Homo sapiens 
2022-01-17 | E-MTAB-11367 | biostudies-arrayexpress
TranscriptomicsDifferentially Expressed Genes Regulating the Progression of Ductal Carcinoma In Situ to Invasive Breast Cancer (Group 3)
We used gene expression profiling of human DCIS and IBC to discover uniquely expressed genes that may also regulate progression. RNA from human samples were extracted, purified, amplified, and evaluated for gene expression using Affymetrix U95Av2 gene expression arrays.
ORGANISM(S): Homo sapiens 
2012-09-29 | E-GEOD-41197 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human ductal carcinoma in situ (DCIS) and invasive component (IDC) from 9 breast cancers to identify novel molecular markers characterizing the transition from DCIS to IDC.
This is a matched-pair analysis of ductal carcinoma in situ (DCIS) and invasive component (IDC) of nine breast ductal carcinoma to identify novel molecular markers characterizing the transition from DCIS to IDC for a better understanding of its molecular biology.
ORGANISM(S): Homo sapiens 
2007-10-02 | E-GEOD-3893 | biostudies-arrayexpress
Sort   by:  
 Page size