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ProteomicsIntegrating intracellular and extracellular proteomic profiling for in-depth investigations of cellular communication in a model of prostate cancer
Cellular communication is essential for cell-cell interactions, maintaining homeostasis and progression of certain disease states. While many studies examine extracellular proteins, the holistic extracellular proteome is often left uncaptured, leaving gaps in our understanding of how all extracellul...
ORGANISM(S): Homo sapiens (Human) 
2023-05-25 | PXD037806 | Pride
Prostate cancer Extracellular proteomics Lc-ms/ms 
TranscriptomicsDifferentially regulated genes induced in Mycobacterium avium subspecies paratuberculosis by in vitro infection of THP-1 human macrophage cell line
Transcriptional profile of Mycobacterium avium subspecies paratuberculosis in in vitro THP-1 (ATCC TIB-202) cell line infection, comparing bacteria grown in host medium and intracellular bacteria recovered from infected THP-1 cells. Two-condition experiment, MAP-K vs. intracellular MAP-THP-1. Biolog...
ORGANISM(S): Mycobacterium avium subsp. paratuberculosis 
2012-05-31 | E-GEOD-32242 | biostudies-arrayexpress
GenomicsCD133+ Intercellsome Mediates Direct Cell-Cell Communication to Offset Intracellular Signaling Deficit
CD133+ Intercellsome Mediates Direct Cell-Cell Communication to Offset Intracellular Signaling Deficit
PRJNA716265 | ENA
TranscriptomicsEffect pck or ppc expression on intracellular ATP
Up-regulation of motility genes and biosynthesis genes were found in the pck expressing high ATP cell by transcriptome analysis while catabolism genes were down-regulated. Keywords: response depends on intracellular ATP concentration derived by pck or ppc overexpression 1. pck or ppc overexpressing ...
ORGANISM(S): Escherichia coli 
2010-06-09 | E-GEOD-8532 | biostudies-arrayexpress
ProteomicsStructural basis for the asymmetric binding of coactivator SRC1 to FXR-RXRα and allosteric communication within the complex
In this study, we employed an integrative approach to investigate the interaction between FXR-RXRα-DNA complex and the entire coactivator SRC1-NRID (nuclear receptor interaction domain). We constructed a multi-domain model of FXR-RXRα-DNA, highlighting the interface between FXR-DBD and LBD. Using HD...
ORGANISM(S): Homo Sapiens 
2025-02-08 | PXD060593 |
TranscriptomicsDifferent gene expressions in root tips between CLE10 and CLE25 treatment
Cell–cell communication is critical for tissue and organ development. In plants, secretory CLAVATA3/EMBRYO SURROUNDING REGION-related (CLE) peptides function as intercellular signaling molecules in various aspects of tissue development. However, little is known about intracellular signaling pathways...
ORGANISM(S): Arabidopsis thaliana 
2010-09-03 | E-GEOD-19978 | biostudies-arrayexpress
TranscriptomicsmiRNA signatures of intracellular and extracellular fractions from cancer cell lines
For the purpose of finding a novel tumor marker, we conducted microRNA profiling analysis in fractions of cells, exosomes, and culture medium from seven cancer cell lines. Ranking data of the intracellular and extracellular microRNAs obtained by microarray analysis, we found that let-7 microRNA fami...
ORGANISM(S): Homo sapiens 
2010-04-16 | E-GEOD-21350 | biostudies-arrayexpress
UnknownIntracellular detection and communication of a wireless chip in cell.
Not available
S-EPMC7966781 | biostudies-literature
ProteomicsProteomic Characterization of Human Milk Fat Globule Membrane Proteins during a 12 Month Lactation Period
The milk fat globule membrane (MFGM) contains proteins which have been implicated in a variety of health benefits. Milk fat globule membrane proteins were isolated from human milk during a 12 month lactation period and subjected to in solution digestion and liquid chromatography tandem mass spectrom...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-06-24 | MSV000089722 | MassIVE
TranscriptomicsMultifaceted maturation of monocyte-derived dendritic cells stimulated by intracellular bacteria
Background: It has been shown that intracellular pathogens hijack DC functions to evade immune defense mechanisms. In this study, we investigated the responses of human monocyte derived DCs to four intracellular bacteria, Tropheryma whipplei, Coxiella burnetii, Brucella abortus and Orientia tsutsuga...
ORGANISM(S): Homo sapiens 
2015-02-27 | E-GEOD-49016 | biostudies-arrayexpress
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