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TranscriptomicsQuantitative time-course profiling of Plasmodium falciparum transcripts and proteins throughout the 48-hour intraerythrocytic developmental cycle
Quantitative studies of the P. falciparum transcriptome have shown that the tightly controlled progression of the parasite through the intraerythrocytic developmental cycle (IDC) is accompanied by a continuous gene expression cascade where most expressed genes exhibit a single transcriptional peak. ...
ORGANISM(S): Plasmodium falciparum 
2011-06-07 | E-GEOD-24416 | biostudies-arrayexpress
TranscriptomicsDynamics of epigenetic regulation of gene expression during Plasmodium falciparum life cycle
In order to study the role of chromatin remodeling in transcriptional regulation associated with the progression of the P. falciparum intraerythrocytic development cycle (IDC), we mapped the temporal pattern of chromosomal association with histone H3 and H4 modifications using chromatin-immunoprecip...
ORGANISM(S): Plasmodium falciparum 
2013-03-02 | E-GEOD-39238 | biostudies-arrayexpress
TranscriptomicsTranscription profile of the Plasmodium falciparum intraerythrocytic cycle
This experiment characterizes the transcriptome of the human malaria parasite, P. falciparum at 8 different stages of the intraerythrocytic cycle Examination of polyA selected RNA in Plasmodium falciparum 3D7 strain at 8 different stages using RNA-seq
ORGANISM(S): Plasmodium falciparum 3D7 
2010-10-28 | E-GEOD-23865 | biostudies-arrayexpress
GenomicsEpigenetic profile of the Plasmodium falciparum intraerythrocytic cycle
This experiment characterizes the localisation of H2A.Z, H3K9ac and H3K4me3 in the epigenome of the human malaria parasite, P. falciparum at 4 different stages of intraerythrocytic development. Examination of H2A.Z, H3K9ac, H3K4me3 and mono-nucleosomal input in 3D7 strain at 4 different stages and H...
ORGANISM(S): Plasmodium falciparum 3D7 
2010-10-28 | E-GEOD-23867 | biostudies-arrayexpress
TranscriptomicsCharacterization and gene expression analysis of the cir multi-gene family of Plasmodium chabaudi chabaudi (AS)
The pir genes comprise the largest multi-gene family in Plasmodium, with members found in P. vivax, P. knowlesi and the rodent malaria species. Despite comprising up to 5% of the parasite genome, little is known about the functions of the proteins encoded by pir genes. P. chabaudi causes chronic inf...
ORGANISM(S): Plasmodium chabaudi chabaudi 
2012-05-31 | E-GEOD-33333 | biostudies-arrayexpress
TranscriptomicsComparison of relative transcript and protein abundance in Plasmodium falciparum schizont stage parasites
Background: Malaria is a one of the most important infectious diseases and is caused by parasitic protozoa of the genus Plasmodium. Previously, the quantitative characterization of the P. falciparum transcriptome demonstrated that the strictly controlled progression of these parasites through their ...
ORGANISM(S): Plasmodium falciparum 
2010-05-05 | E-GEOD-13251 | biostudies-arrayexpress
Transcriptomicsextracellular calcium chelation experiment_P. falciparum (lab strain 3d7) schizonts untreated vs P. falciparum (lab strain 3d7) reference RNA pool
Calcium is a universal second messenger molecule which plays a significant role in several biological processes. Presence of calcium sensors (calmodulins) and calcium-dependent protein kinases in Plasmodium species suggests an important role of calcium-dependent signaling pathways in the regulation ...
ORGANISM(S): Plasmodium falciparum 3D7 
2012-07-14 | E-GEOD-33834 | biostudies-arrayexpress
Transcriptomicsextracellular calcium chelation experiment_P. falciparum (lab strain 3d7) schizonts treated with ionomycin vs P. falciparum (lab strain 3d7) reference RNA pool
Calcium is a universal second messenger molecule which plays a significant role in several biological processes. Presence of calcium sensors (calmodulins) and calcium-dependent protein kinases in Plasmodium species suggests an important role of calcium-dependent signaling pathways in the regulation ...
ORGANISM(S): Plasmodium falciparum 3D7 
2012-07-14 | E-GEOD-33835 | biostudies-arrayexpress
TranscriptomicsP. falciparum (lab strain 3d7) schizonts treated with A23187 vs P. falciparum (lab strain 3d7) reference RNA pool
Calcium is a universal second messenger molecule which plays a significant role in several biological processes. Presence of calcium sensors (calmodulins) and calcium-dependent protein kinases in Plasmodium species suggests an important role of calcium-dependent signaling pathways in the regulation ...
ORGANISM(S): Plasmodium falciparum 3D7 
2012-07-14 | E-GEOD-33797 | biostudies-arrayexpress
TranscriptomicsP. falciparum (lab strain 3d7) schizonts treated with ionomycin vs P. falciparum (lab strain 3d7) reference RNA pool
Calcium is a universal second messenger molecule which plays a significant role in several biological processes. Presence of calcium sensors (calmodulins) and calcium-dependent protein kinases in Plasmodium species suggests an important role of calcium-dependent signaling pathways in the regulation ...
ORGANISM(S): Plasmodium falciparum 3D7 
2012-07-14 | E-GEOD-33796 | biostudies-arrayexpress
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