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Proteomics2D-PAGE coupled with nLC-MS/MS-based identification of differentialy expressed proteins and tumorigenic pathways in MCF7 breast cancer cell line transfected for JTB protein silencing
Identification of new cancer-associated genes/proteins, characterization of their expression vari-ation, the interactomics-based assessment of differentially expressed genes/proteins (DEGs/DEPs), and understanding the tumorigenic pathways and biological processes involved in BC genesis and progressi...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD046265 | Pride
Breast cancer (bc)  mcf7  jtb protein silencing  overexpressed jtb-interactome  downregulated jtb-interactome  tumorigenic pathways 
UnknownTwo-Dimensional-PAGE Coupled with nLC-MS/MS-Based Identification of Differentially Expressed Proteins and Tumorigenic Pathways in MCF7 Breast Cancer Cells Transfected for JTB Protein Silencing.
Not available
S-EPMC10673289 | biostudies-literature
UnknownIdentification of a pro-protein synthesis osteosarcoma subtype for predicting prognosis and treatment.
Not available
S-EPMC11252356 | biostudies-literature
TranscriptomicsUnexpected roles of ATP11B in platinum resistance
Platinum compounds display clinical activity against a wide variety of solid tumors. However, resistance to these agents is a major limitation in cancer therapy. Reduced platinum uptake and increased platinum export are examples of resistance mechanisms that limit the extent of DNA damage. Here, we ...
ORGANISM(S): Homo sapiens 
2013-01-23 | E-GEOD-43694 | biostudies-arrayexpress
TranscriptomicsTranscriptional changes in soybean nodules with the loss of expression of GmbHLHm1
This study was conducted to investigate the changes in gene expression that occurs with the silencing of GmbHLHm1. GmbHLHm1 is a membrane localised DNA binding transcription factor that is important for nodule development. Its activity is linked to ammonium transport. 7 samples
ORGANISM(S): Glycine max 
2014-03-14 | E-GEOD-55896 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Andigena SP5G RNAi leaves, tubers and tuber sprouts
To analyze the gene regulatory network controlled by SP5G in potato, we hybridized an Agilent 60-mer microarray with probes corresponding to the RNA extracted out of leaf, tuber and tuber sprout tissues from WT and StSP5Gi lines.
ORGANISM(S): Solanum tuberosum 
2018-10-17 | E-MTAB-6438 | biostudies-arrayexpress
Transcriptomicsdark hypocotyls tor rnai-Dark hypocotyls TOR RNAi
fapesp-bra-inra-10-01_bioen_hypocotyl - dark hypocotyls tor rnai - Transcriptional comparison between 2 TOR RNAi mutants versus GUS control. - Sowing after 24h imbibition at 4M-BM-0C in the dark, on MS1/5, no sucrose, 10 mM ethanol, 8 g/l agar, vertical growth with 3h light, 6 days growth in the dar...
ORGANISM(S): Arabidopsis thaliana 
2012-10-10 | E-GEOD-41404 | biostudies-arrayexpress
TranscriptomicsA global regulatory mechanism for activating an exon network required for neurogenesis
The vertebrate and neural-specific SR-related protein nSR100/SRRM4 regulates an extensive program of alternative splicing with critical roles in nervous system development. However, the mechanism by which nSR100 controls its target exons is poorly understood. We demonstrate that nSR100-dependent neu...
ORGANISM(S): Mus musculus 
2014-09-11 | E-GEOD-57278 | biostudies-arrayexpress
TranscriptomicsAnthracycline treatment and resistance in four human cancer cell lines
Reliable clinical tests for predicting cancer chemotherapy response are not available and individual markers failed to correctly predict resistance against anticancer agents. We hypothesized that gene expression patterns attributable to chemotherapy-resistant cells can be used as a classification to...
ORGANISM(S): Homo sapiens 
2010-04-14 | E-GEOD-3929 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis mutants (elo2, elo3, drl1-2 and ang4) vs the wild type Ler strain
Microarray transcript profiling and RNA interference are two new technologies crucial for large-scale gene function studies in multicellular eukaryotes. Both rely on sequence-specific hybridization between complementary nucleic acid strands, inciting us to create a collection of gene-specific sequen...
ORGANISM(S): Arabidopsis thaliana 
2004-05-07 | E-MEXP-30 | biostudies-arrayexpress
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