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To investigate the effects of the differences seen in the JUND binding patterns between LEW, WKY and WKY.LCrgn2 bone marrow derived macrophages (BMDMs), we have 1) analysed gene expression changes over a time course (4 time points: 0,2,4 and 8 hrs) of stimulation with lipopolysaccharide (LPS) using ...
ORGANISM(S): Rattus norvegicus 
RNA-seq following JunD depletion
Background: MLL-rearranged (MLLr) acute myeloid leukemia (AML) and acute lymphoid leukemia (ALL) involve reciprocal oncogenic translocations of the KMT2A/KMT2B (MLL1/MLL2) gene on chromosome 11q23 with various translocation partner genes, which yields to chimeric MLL fusion proteins (MLL-FPs). Menin...
ORGANISM(S): Homo sapiens (Human) 
2026-07-28 | PXD068124 | Pride
Background: MLL-rearranged (MLLr) acute myeloid leukemia (AML) and acute lymphoid leukemia (ALL) involve reciprocal oncogenic translocations of the KMT2A/KMT2B (MLL1/MLL2) gene on chromosome 11q23 with various translocation partner genes, which yields to chimeric MLL fusion proteins (MLL-FPs). Menin...
ORGANISM(S): Homo sapiens (Human) 
2026-07-28 | PXD068061 | Pride
Background: MLL-rearranged (MLLr) acute myeloid leukemia (AML) and acute lymphoid leukemia (ALL) involve reciprocal oncogenic translocations of the KMT2A/KMT2B (MLL1/MLL2) gene on chromosome 11q23 with various translocation partner genes, which yields to chimeric MLL fusion proteins (MLL-FPs). Menin...
ORGANISM(S): Homo sapiens (Human) 
2026-07-28 | PXD068056 | Pride
Background: MLL-rearranged (MLLr) acute myeloid leukemia (AML) and acute lymphoid leukemia (ALL) involve reciprocal oncogenic translocations of the KMT2A/KMT2B (MLL1/MLL2) gene on chromosome 11q23 with various translocation partner genes, which yields to chimeric MLL fusion proteins (MLL-FPs). Menin...
ORGANISM(S): Homo sapiens (Human) 
2026-07-28 | PXD067825 | Pride
Regulation of cigarette smoke-induced airway inflammation by JunD
JunD cistrome of the human myometrium at during term pregnancy and labour
Cigarette smoke (CS)-induced airway inflammation is an important pathologic feature of chronic obstructive pulmonary disease (COPD). Recent studies suggest a potential role of JunD in the regulation of inflammation, but its role in CS-induced airway inflammation has not been reported. This study aim...
ORGANISM(S): Homo sapiens 
2020-12-09 | GSE162902 | GEO
RNA-seq performed in Min6 cells during glucolipotoxicity after CRISPR-mediated depletion of JunD
ORGANISM(S): Mus musculus 
2019-08-16 | GSE115239 | GEO
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