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MetabolomicsRegulation of drug resistance to enrofloxacin in Pasteurella multocida strains from cattle by quorum-sensing acyl-homoserine lactone signaling molecules

Pasteurella multocida (Pm) is a significant cause of respiratory disease in beef cattle, with serious consequences for the cattle industry. The bacterial quorum-sensing (QS) system is used for communication and regulation of various processes, including bacterial growth, virulence, biofilm format...

2025-12-18 | MTBLS13502 | MetaboLights
TranscriptomicsA New Class of Homoserine Lactone Quorum Sensing Signals
Quorum sensing is a term used to describe cell-to-cell communication that allows cell density-dependent gene expression. Many Gram-negative bacteria use acyl-homoserine lactone (acyl-HSL) synthases to generate fatty acyl-HSL quorum sensing signals, which function with signal receptors to control exp...
ORGANISM(S): Rhodopseudomonas palustris CGA009 
2010-05-25 | E-GEOD-10642 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of effect of N-(3-oxo-dodecanoyl) homoserine lactone on S. cerevesiae
We examined whether the budding yeast Saccharomyces cerevisiae can sense chemical signals from prokaryotes, specifically a variety of quorum sensing molecules from different bacteria species and from Candida albicans. We found that only N-acyl-3-oxo-dodecanoyl homoserine lactone (C12) from the oppor...
ORGANISM(S): Saccharomyces cerevisiae 
2020-03-02 | E-MTAB-4802 | biostudies-arrayexpress
GenomicsKentucky assay: whiskey lactone
Kentucky assay: whiskey lactone
PRJNA509875 | ENA
TranscriptomicsThe activity of Rhodopseudomonas palustris p-coumaroyl-homoserine lactone-responsive transcription factor RpaR
The Rhodopseudomonas palustris transcriptional regulator RpaR responds to the RpaI-synthesized quorum-sensing signal p-coumaroyl-homoserine lactone (pC-HSL). Other characterized RpaR homologs respond to fatty acyl-HSLs. We show here that RpaR functions as a transcriptional activator, which binds dir...
ORGANISM(S): Rhodopseudomonas palustris 
2011-05-15 | E-GEOD-27365 | biostudies-arrayexpress
TranscriptomicsThe contribution of QS components vjbR and N-dodecanoyl homoserine lactone on gene regulation in Brucella melitensis
This SuperSeries is composed of the following subset Series: GSE13527: Expt 1: The contribution of vjbR and N-dodecanoyl homoserine lactone on gene regulation in Brucella melitensis GSE13633: Expt 2: The contribution of vjbR and N-dodecanoyl homoserine lactone on gene regulation in Brucella melitens...
ORGANISM(S): Brucella melitensis 16M 
2010-04-23 | E-GEOD-13634 | biostudies-arrayexpress
ProteomicsA quantitative map of beta-lactone induced virulence regulation
Beta-lactones have recently been introduced as the first selective ClpP inhibitors that attenuate virulence of both sensitive Staphylococcus aureus and multiresistant strains (MRSA). Although previous knockout studies showed that ClpP is essential for S. aureus alpha-toxin production a link between ...
ORGANISM(S): Staphylococcus aureus 
2017-02-08 | PXD004680 | Pride
Proteomics Chemical knockout S. aureus clpp Antivirulence Activity-based protein profiling 
TranscriptomicsResponse to different N-acyl homoserine lactones and N-acyl homoserine lactones-pretreated plants to secondary challenge with flg22.
In order to gain coherent insights into plant responses we performed transcriptional analysis of Arabidopsis seedling after treatment with three different AHLs: N-hexanoyl-L-homoserine lactone (C6-HSL), N-3-oxo-decanoyl-L-homoserine lactone (oxo-C10-HSL), and N-3-oxo-tetradecanoyl-L-homoserine lacto...
ORGANISM(S): Arabidopsis thaliana 
2014-11-26 | E-GEOD-52979 | biostudies-arrayexpress
GenomicsKentucky assay: isoamyl acetate and whiskey lactone mixture
Kentucky assay: isoamyl acetate and whiskey lactone mixture
PRJNA509874 | ENA
TranscriptomicsTranscription profiling of Pseudomonas aeruginosa Quorum Sensing Circuit
To better understand the role of QscR in P. aeruginosa gene regulation and to better understand the relationship between QscR, LasR and RhlR control of gene expression we used transcription profiling to identify a QscR-dependent regulon. Our analysis revealed that QscR activates some genes and repre...
ORGANISM(S): Pseudomonas aeruginosa 
2008-06-12 | E-GEOD-4026 | biostudies-arrayexpress
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