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TranscriptomicsTranscript profiling of Lymphangioleiomyomatosis (LAM) nodules in Human Patients
Lymphangioleiomyomatosis (LAM) is characterized by cystic lung destruction caused by smooth, muscle-like LAM cells which have mutations in the tumor suppressor genes Tuberous Sclerosis Complex (TSC) 1 or 2, and the capacity to metastasize. Since chemokines and their receptors function in chemotaxis ...
ORGANISM(S): Homo sapiens 
2008-12-30 | E-GEOD-12027 | biostudies-arrayexpress
ProteomicsProfiling the LAM family of contact-site tethers provides mechanistic insights into their regulation and function
Membrane contact sites are molecular bridges between organelles that are sustained by tethering proteins and enable organelle communication. The endoplasmic reticulum (ER) membrane harbors many distinct families of tether proteins that enable the formation of contacts with all other organelles. One ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD051014 | Pride
Membrane contact sites  endoplasmic reticulum  lam protein family  proximity labelling  abolish 
ProteomicsProfiling the LAM family of contact-site tethers provides mechanistic insights into their regulation and function
Membrane contact sites are molecular bridges between organelles that are sustained by tethering proteins and enable organelle communication. The endoplasmic reticulum (ER) membrane harbors many distinct families of tether proteins that enable the formation of contacts with all other organelles. One ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2025-03-10 | PXD051047 | Pride
Membrane contact sites  endoplasmic reticulum  lam protein family  proximity labelling  abolish 
UnknownProfiling the LAM Family of Contact Site Tethers Provides Insights into Their Regulation and Function.
Not available
S-EPMC12033502 | biostudies-literature
ProteomicsMycobacterium tuberculosis encodes a YhhN family membrane protein with lysoplasmalogenase activity that protects against toxic effects of lysolipids
Mycobacterium tuberculosis (M.tb) resides in human macrophages where it exploits host lipids for survival. Little is known about the interaction between M.tb and macrophage plasmalogens, the subclass of glycerophospholipids having a vinyl-ether bond at sn-1. Lysoplasmalogens, produced from plasmalog...
ORGANISM(S): Mycobacterium tuberculosis 
2022-05-20 | PXD027875 | Pride
Lysoplasmalogenase Phospholipase a Macrophage Cell injury and protection Mycobacterium tuberculosis rv1401 gene Lysoplasmalogen Spheroplasts Cell-wall-deficient (cwd) Lysophospholipids Mycobacterium smegmatis Yhhn protein 
UnknownSterol biosensor reveals LAM-family Ltc1-dependent sterol flow to endosomes upon Arp2/3 inhibition.
Not available
S-EPMC7265315 | biostudies-literature
TranscriptomicsExpression data from Drosophila melanogaster err mutant animals vs. wild type animals at a mid-second instar larval time
Cancer cells utilize a unique form of aerobic glycolysis, called the Warburg effect, to efficiently produce the macromolecules required for proliferation. Here we show that a metabolic program related to the Warburg effect is used during normal Drosophila development and regulated by the fly orthol...
ORGANISM(S): Drosophila melanogaster 
2011-02-02 | E-GEOD-23336 | biostudies-arrayexpress
UnknownEnhanced binding of guanylated poly(A) RNA by the LaM domain of LARP1.
Not available
S-EPMC11259064 | biostudies-literature
UnknownOverexpression of a LAM domain containing RNA-binding protein LARP1c induces precocious leaf senescence in Arabidopsis.
Not available
S-EPMC3887763 | biostudies-literature
UnknownThe complete chloroplast genome and phylogenetic analysis of Cyperus malaccensis Lam (Cyperaceae).
Not available
S-EPMC10810665 | biostudies-literature
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