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UnknownFocal Epilepsy in Individuals with Laron Syndrome.
Not available
S-EPMC9501736 | biostudies-literature
UnknownLaron Syndrome Research Paves the Way for New Insights in Oncological Investigation.
Not available
S-EPMC7696416 | biostudies-literature
ProteomicsBiomarkers of favorable immune capacity in growth hormone receptor knockout pig model
Laron Syndrome (LS) is a rare hereditary disease in humans caused by a mutation in the growth hormone receptor gene which leads to high levels of circulating GH [1]. The disease is characterized by short statue, obesity, transient hypoglycemia during youth and low incidences of cancer and diabetes [...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2023-07-20 | PXD038772 | Pride
Quantitative label-free lc-ms/ms  laron syndrome  ghr-ko  porcine model  immune function 
UnknownMicroRNA 132-3p Is Upregulated in Laron Syndrome Patients and Controls Longevity Gene Expression.
Not available
S-EPMC8584665 | biostudies-literature
TranscriptomicsGH-resistant (Laron) mice: gene therapy with a liver-specific GH receptor causes unbalanced upregulation of female-biased and growth-related genes
Growth hormone (GH) receptor (GHR) mutations give rise to GH-resistance (Laron syndrome). We previously treated GH-resistant Ghr-/- mice (Laron mice) with adeno-associated virus (AAV) delivering mouse (m)Ghr controlled by a constitutively active liver-specific promoter (HLP). A single injection of A...
ORGANISM(S): Mus musculus 
2026-06-18 | GSE289769 | GEO
UnknownGeneration of GHR-modified pigs as Laron syndrome models via a dual-sgRNAs/Cas9 system and somatic cell nuclear transfer.
Not available
S-EPMC5828148 | biostudies-literature
GenomicsGH-resistant (Laron) mice: gene therapy with a liver-specific GH receptor causes unbalanced upregulation of female-biased and growth-related genes
GH-resistant (Laron) mice: gene therapy with a liver-specific GH receptor causes unbalanced upregulation of female-biased and growth-related genes
PRJNA1224752 | ENA
UnknownEffectiveness and safety of rhIGF1 therapy in patients with or without Laron syndrome.
Not available
S-EPMC7849377 | biostudies-literature
UnknownEffects of GHR Deficiency and Juvenile Hypoglycemia on Immune Cells of a Porcine Model for Laron Syndrome.
Not available
S-EPMC10135491 | biostudies-literature
UnknownReporting a novel growth hormone receptor gene variant in an Iranian consanguineous pedigree with Laron syndrome: a case report.
Not available
S-EPMC10357607 | biostudies-literature
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