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ProteomicsHuman LC-MS Data in HEK293T overexpressed LATS2
LC-MS data for Enzyme Activity-Independent NANS Stabilizes LATS2 to Drive Growth and Confer Resistance to Endocrine Therapy and CDK4/6 Inhibitors in HR+/HER2- Breast Cancer
ORGANISM(S): Homo sapiens (Human) 
2025-12-14 | PXD065340 | Pride
Human lc-ms lats2 
TranscriptomicsRNA-seq analysis of add-back rescued TALEN-mediated LATS2 knockout HeLa-S3 cells
Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular conte...
ORGANISM(S): Homo sapiens 
2016-07-26 | E-GEOD-66388 | biostudies-arrayexpress
TranscriptomicsRNA-seq analysis of TALEN-mediated LATS2 knockout HeLa-S3 cells
Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular conte...
ORGANISM(S): Homo sapiens 
2016-07-26 | E-GEOD-63537 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of TALEN-mediated LATS2 knockout HeLa-S3 cells
Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular conte...
ORGANISM(S): Homo sapiens 
2016-07-26 | E-GEOD-63534 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of HeLa-S3 cells treated with siRNAs targeting LATS1 and/or LATS2
Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular conte...
ORGANISM(S): Homo sapiens 
2016-07-26 | E-GEOD-63533 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of Lats2 deficient mouse embryonic fibroblasts
Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular conte...
ORGANISM(S): Mus musculus 
2016-07-26 | E-GEOD-63536 | biostudies-arrayexpress
TranscriptomicsmiRNA array profiling of Lats2 deficient mouse embryonic fibroblasts
Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular conte...
ORGANISM(S): Mus musculus 
2016-07-26 | E-GEOD-63532 | biostudies-arrayexpress
GenomicsGenome-wide maps of chromatin state in LATS2-knockout HeLa-S3 cell
Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular conte...
ORGANISM(S): Homo sapiens 
2016-07-26 | E-GEOD-64072 | biostudies-arrayexpress
TranscriptomicsLATS2 regulates repressive epigenetic integrity via regulation of Polycomb repressive complex 2
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2016-07-25 | E-GEOD-63538 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiling of mouse embryonic fibroblasts upon contact inhibition
Chromatin modifying activities for construction of appropriate epigenetic landscapes by polycomb repressive complex 2 (PRC2) play an essential role in development and tumorigenesis. However, the spatiotemporal mechanisms by which PRC2 achieves diverse epigenomes for specific tissue or cellular conte...
ORGANISM(S): Mus musculus 
2016-07-26 | E-GEOD-63535 | biostudies-arrayexpress
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