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GenomicsAutosomal dominant gain-of-function mutations in LCP1 cause syndromiceneutropenia and immunodeficiency-
Autosomal dominant gain-of-function mutations in LCP1 cause syndromiceneutropenia and immunodeficiency-
PRJNA1063354 | ENA
GenomicsIL7R depletion mitigates neuroinflammation and ischemic stroke via AKT dephosphorylation dependent LCP1 suppression in mice
IL7R depletion mitigates neuroinflammation and ischemic stroke via AKT dephosphorylation dependent LCP1 suppression in mice
PRJNA1381653 | ENA
GenomicsIL7R depletion mitigates neuroinflammation and ischemic stroke via AKT dephosphorylation dependent LCP1 suppression in mice
IL7R depletion mitigates neuroinflammation and ischemic stroke via AKT dephosphorylation dependent LCP1 suppression in mice
PRJNA1387478 | ENA
UnknownExosomal Transfer of LCP1 Promotes Osteosarcoma Cell Tumorigenesis and Metastasis by Activating the JAK2/STAT3 Signaling Pathway.
Not available
S-EPMC7452114 | biostudies-literature
UnknownTargeted deletion of the zebrafish actin-bundling protein L-plastin (lcp1).
Not available
S-EPMC5749806 | biostudies-literature
UnknownLCP1 promotes ovarian cancer cell resistance to olaparib by activating the JAK2/STAT3 signalling pathway.
Not available
S-EPMC11601053 | biostudies-literature
TranscriptomicsAutosomal dominant gain-of-function mutations in LCP1 cause syndromiceneutropenia and immunodeficiency-
To further evaluate the impact of LCP1 dysfunction on hematopoiesis, we performed single-cell RNA sequencing (scRNA-seq) for bone marrow cells from patients and two matched healthy controls. Total 39, 028 cells were included in the sequential analysis after quality control.
ORGANISM(S): Homo sapiens 
2026-03-01 | GSE252973 | GEO
UnknownLCP1 upregulation via EGFR signaling promotes oral cancer progression through the JAK2/STAT3/IL-1β axis.
Not available
S-EPMC12495854 | biostudies-literature
UnknownLcp1 Is a Phosphotransferase Responsible for Ligating Arabinogalactan to Peptidoglycan in Mycobacterium tuberculosis.
Not available
S-EPMC4981717 | biostudies-literature
UnknownLCP1 knockdown in monocyte-derived macrophages: mitigating ischemic brain injury and shaping immune cell signaling and metabolism.
Not available
S-EPMC10750214 | biostudies-literature
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