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ProteomicsA qualitative proteome-wide lysine crotonylation profiling reveals protein modification alteration in the leukocyte extravasation pathway in systemic lupus erythematosus
Background Systemic lupus erythematosus (SLE) is a severe systemic autoimmune disease with multiple manifestations. Lysine crotonylation (Kcr) is a newly discovered post-translational modification (PTM) epigenetic pattern which may affect gene expression and linked to diseases causally. Methods We ...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD042217 | Pride
Systemic lupus erythematosus  proteome  crotonylation  post-translational modifications  leukocyte extravasation 
GenomicsEffects of PDGFRa-lineage leukocyte extravasation to skin in atopic dermatitis
Effects of PDGFRa-lineage leukocyte extravasation to skin in atopic dermatitis
PRJNA702124 | ENA
TranscriptomicsEffects of PDGFRa-lineage leukocyte extravasation to skin in atopic dermatitis
The circulating leukocyte population contains a fraction of cells derived from progenitors that had transient PDGFRa expression during embryonic development (PDGFRa-lineage). During inflammation, extravasated leukocytes in inflamed tissue modify the tissue-resident leukocyte population and crosstalk...
ORGANISM(S): Mus musculus 
2022-07-27 | GSE166854 | GEO
UnknownUropod elongation is a common final step in leukocyte extravasation through inflamed vessels.
Not available
S-EPMC3405502 | biostudies-literature
UnknownQualitative Proteome-wide Lysine Crotonylation Profiling Reveals Protein Modification Alteration in the Leukocyte Extravasation Pathway in Systemic Lupus Erythematosus.
Not available
S-EPMC10688171 | biostudies-literature
UnknownOrphan GPR84 facilitates uropod de-adhesion at multiple steps during leukocyte extravasation
Not available
S-SCDT-10_1038-S44319-026-00923-0 | biostudies-other
UnknownExtracellular matrices regulate extravasation journey of leukocytes and inflammatory tissue fate.
Not available
S-EPMC12677898 | biostudies-literature
UnknownESAM supports neutrophil extravasation, activation of Rho, and VEGF-induced vascular permeability.
Not available
S-EPMC2118342 | biostudies-literature
UnknownExtravasation of leukocytes in comparison to tumor cells.
Not available
S-EPMC2627905 | biostudies-literature
UnknownPlatelets Guide Leukocytes to Their Sites of Extravasation.
Not available
S-EPMC4859536 | biostudies-literature
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