localized prostate cancer

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Organisms

Homo sapiens (148)
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Tissue

Prostate gland (5)
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Disease

Prostate adenocarcinoma (16)
Prostate cancer (3)
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Carcinoma (1)
Malignant neoplasm of ovary (1)
Pancreatic cancer (1)
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Illumina HiSeq 2000 (1)
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CHEBI ID

CHEBI:18300 (3)
CHEBI:16709 (3)
CHEBI:30769 (3)
CHEBI:15741 (3)
CHEBI:7916 (3)
CHEBI:15963 (2)
CHEBI:42111 (2)
CHEBI:4178 (2)
CHEBI:17270 (2)
CHEBI:30794 (2)
CHEBI:17113 (2)
CHEBI:17148 (2)
CHEBI:18089 (2)
CHEBI:16831 (2)
CHEBI:17802 (2)
CHEBI:24462 (2)
CHEBI:15350 (2)
CHEBI:741548 (2)
CHEBI:16610 (2)
CHEBI:15728 (2)
CHEBI:16552 (2)
CHEBI:16927 (2)
CHEBI:70958 (2)
CHEBI:48928 (2)
CHEBI:24266 (2)
CHEBI:18012 (2)
CHEBI:17562 (2)
CHEBI:17515 (2)
CHEBI:15746 (2)
CHEBI:15676 (2)

Metabolite Name

Glutaric acid (2)
Homovanillic acid (2)
Pantothenic acid (2)
Maleic acid (2)
Suberic acid (2)
3-Indoleacetic acid (1)
Oleoyl CoA (1)
N6,N6-dimethyladenosine (1)
Mannose-6-phosphate (1)
Glycerol 2-phosphate (1)
Galacturonate 1-phosphate (1)
Cytidine 5'-monophosphate (5'-CMP) (1)
Acetyl CoA (1)
4-methylcatechol sulfate (1)
2,3-diphosphoglycerate (1)
(N(1) + N(8))-acetylspermidine (1)
Prostaglandin-c2 (1)
(2'E,4'Z,8E)-Colneleic acid (1)
4-Acetamido-2-aminobutanoic acid (1)
4-Hydroxy-2-oxoglutaric acid (1)
2,4-Dinitrotoluene (1)
Erythro-3-Hydroxy-Ls-aspartate (1)
4-Chloro-17alpha-methyl-17beta-hydroxy-4-androsten-3-one (1)
N,N-Dimethyl-1,4-phenylenediamine (1)
3,4-Methylenedioxyamphetamine (1)
(E)-3-(4-Hydroxyphenyl)-2-propenal (1)
2-Hydroxy-3-(4-hydroxyphenyl)propenoic acid (1)
2-Oxo-4-phenylbutyric acid (1)
(R)-3-Ureidoisobutyrate (1)
Yamogenin (1)

First Public Date

2014 (39)
2019 (21)
2026 (20)
2023 (17)
2025 (13)
2024 (12)
2013 (11)
2017 (10)
2020 (9)
2021 (6)
2018 (6)
2015 (6)
2022 (5)
2016 (1)

Study status

Completed (1)

Study type

Transcription profiling by array (78)
RNA-seq of coding RNA (12)
ChIP-seq (10)
Other (5)
Unknown experiment type (4)
Genotyping by array (3)
Transcription profiling by RT-PCR (3)
Methylation profiling by array (3)
Methylation profiling by high throughput sequencing (3)
Comparative genomic hybridization by array (2)
ChIP-chip by tiling array (1)
Cell line - High-throughput sequencing (1)
ChIP-chip by array (1)
Interventional (1)

Release Date

2022 (202)
2021 (182)
2023 (180)
2020 (148)
2025 (139)
2024 (126)
2019 (107)
2017 (101)
2016 (100)
2018 (93)
2015 (85)
2014 (72)
2012 (44)
2013 (38)
2011 (38)
2010 (32)
2026 (22)
2009 (21)
2008 (20)
2007 (10)
2005 (5)
2003 (2)
2002 (2)
2004 (1)
2001 (1)
1999 (1)
1998 (1)

Lab affiliation

Faculty of Helath Sciences. University of Copenhagen. Copenhagen. Denmark (3)
Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark (2)
Molecular Physiology & Biophysics Department, Wright Lab, University of Iowa, USA (1)
Prof. Bettina Warscheid Funktionelle Proteomik Biologie II Albert-Ludwigs-Universität Freiburg Schänzlestr. 1 79104 Freiburg (1)
Johns Hopkins University, School of Medicine, Department of Pathology (1)
University of Copenhagen. Department of Drug Design and Pharmacology (1)
Instituto de Ciências Biomédicas, Departamento de Parasitologia, Universidade de São Paulo, USP, São Paulo, Brazil. (1)
Department of Veterinary disease biology. Faculty of health sciences. University of Copenhagen. Copehnagen. Denmark (1)
Prof. Dr. Axel Imhof Histone Modifications Group Zentrallabor für Proteinanalytik BioMedical Center Faculty of Medicine Ludwig-Maximilians-University of Munich Großhadernerstr. 9 82152 Planegg-Martinsried GERMANY (1)
Center for Translational Research and Molecular Biology of Cancer, Maria Sklodowska-Curie National Research Institute of Oncology Gliwice Branch, Gliwice, Poland (1)
Department of Biology, Institute of Molecular Systems Biology, ETH Zurich, Zurich, CH-8093, Switzerland ( lab head ) (1)
Proteomics Platform CIC bioGUNE Bizkaia Tech. Park Build. 800 Derio 48160 Spain (1)
Harry Perkins Institute of Medical Research and ARC Centre of Excellence in Synthetic Biology, QEII Medical Centre, Nedlands, Western Australia 6009, Australia (1)
Associate Professor, Cedars-Sinai Medical Center, Surgery (1)
Director Stony Brook Cancer Center (1)
IVS. University of Copenhagen (1)
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, United States (1)
Proteomics Platform, Broad Institute of MIT and Harvard (1)
Cedars-Sinai Medical Center (1)
Department of Radiology Canary Center at Stanford for Cancer Early Detection Stanford School of Medicine Stanford University (1)

Location

United States (1)

Keyword

Interleukin-12 (1)
Albumin-Bound Paclitaxel (1)
Carboplatin (1)
Trastuzumab (1)

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Metabolic profiling of prostate cancer in skeletal microenvironments identifies G6PD as a key mediator of growth and survival

The spread of cancer to bone is invariably fatal, with complex cross-talk between tumor cells and the bone microenvironment responsible for driving disease progression. By combining in silico analysis of patient datasets with metabolomic profiling of prostate cancer cells cultured with bone cells...

2024-08-19 | MTBLS3973 | MetaboLights

Mitochondrial KMT9 methylates DLAT to control pyruvate dehydrogenase activity and prostate cancer growth

Prostate cancer (PCa) growth depends on de novo lipogenesis controlled by the mitochondrial pyruvate dehydrogenase complex (PDC). In this study, we identified lysine methyltransferase (KMT)9 as a novel regulator of PDC activity. KMT9 is localized in mitochondria of PCa cells, but not in mitochond...

2024-12-10 | MTBLS2452 | MetaboLights

Serum organic acid metabolites can be used as potential biomarkers to identify prostatitis, benign prostatic hyperplasia, and prostate cancer (Untargeted assay)

BACKGROUND: Noninvasive methods for the early identify diagnosis of prostatitis, benign prostatic hyperplasia (BPH), and prostate cancer (PCa) are current clinical challenges.

METHODS: The serum metabolites of 20 healthy individuals and patients with prosta...

2023-04-17 | MTBLS6039 | MetaboLights

Serum organic acid metabolites can be used as potential biomarkers to identify prostatitis, benign prostatic hyperplasia, and prostate cancer (Targeted organic acid assay)

BACKGROUND: Noninvasive methods for the early identify diagnosis of prostatitis, benign prostatic hyperplasia (BPH) and prostate cancer (PCa) are current clinical challenges.

METHODS: The serum metabolites of 20 healthy individuals and patients with prostat...

2023-04-17 | MTBLS6038 | MetaboLights

Integrated Proteogenomic Characterization of Localized Prostate Cancer Identifies Biological Insights and Subtype-Specific Therapeutic Strategies

We profiled the genome, transcriptome, proteome and phosphoproteome of 145 cases of localized prostate cancer (PCa) in Chinese patients and revealed three subtypes with distinct molecular features. We integrated multi-omic data to refine molecular subtyping of localized PCa, and identified NANS as a...

ORGANISM(S): Homo Sapiens

PXD056748 |

Epigenomic alterations in localized and advanced prostate cancer

Here we used Illumina NGS for high-throughput profiling of the DNA methylome in seven human benign prostate tissues, seven human primary prostate cancer and six human castration resistant prostate cancer patient samples. These data were used to profile the CpG cytosine methylation pattern at single ...

ORGANISM(S): Homo sapiens

2013-07-03 | E-GEOD-41701 | biostudies-arrayexpress

The proteome of localized prostate cancer, part 5

Proteome characterization of gland confined prostate tumors and non-malignant prostate tissue. Whole cell protein extracts were purified from FFPE radical prostatectomy specimens for a total of 28 tumor samples and 8 adjacent non-malignant prostate tissues. Associated ProteomeXchange identifiers: PX...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-08-18 | MSV000080067 | MassIVE

The proteome of localized prostate cancer, part 3

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-08-18 | MSV000080070 | MassIVE

The proteome of localized prostate cancer, part 6

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-08-18 | MSV000080065 | MassIVE

The proteome of localized prostate cancer, part 4

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-08-18 | MSV000080068 | MassIVE