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MetabolomicsDistinct metabolic profiles in lung adenocarcinomas presenting as solid or ground-glass opacities

Metabolomic profiling provides real-time insights into tissue physiology and upstream molecular events. Despite its potential in cancer research, large-scale integrative studies in lung adenocarcinoma (LUAD) remain scarce. We analyzed 262 tissue samples from 165 LUAD patients using metabolomic, t...

2025-12-23 | MTBLS13565 | MetaboLights
ProteomicsAssessment of Serological Early Biomarker Candidates for Lung Adenocarcinoma by using Multiple Reaction Monitoring-Mass Spectrometry
Purpose: Serum markers that enable diagnosis in the early stage of lung cancer have not been discovered. We have developed a LC-MRM-MS assay for the identification of potential early marker proteins for lung adenocarcinoma. Experimental design: LC-MRM-MS assay was used for measuring the level of 35 ...
ORGANISM(S): Homo Sapiens 
2021-01-24 | PXD014683 | panorama
MetabolomicsInvestigation of metabolomic blood biomarkers for detection of adenocarcinoma lung cancer (test/validation)
Not available
ORGANISM(S): Homo sapiens 
ST000386 | MetabolomicsWorkbench
ProteomicsGlycoproteomics analysis of triple wild-type lung adenocarcinoma tissue samples
Glycoproteomics analysis of triple wild-type lung adenocarcinoma tissue samples for the publication of the same name.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-11-18 | MSV000096450 | MassIVE
MetabolomicsInvestigation of metabolomic blood biomarkers for detection of adenocarcinoma lung cancer (training set)
Not available
ORGANISM(S): Homo sapiens 
ST000385 | MetabolomicsWorkbench
TranscriptomicsSmoking Status Impacts microRNA Mediated Prognosis and Lung Adenocarcinoma Biology
Cigarette smoke is associated with the majority of lung cancers: however, 25% of lung cancer patients are non-smokers, and half of all newly diagnosed lung cancer patients are former smokers. Lung tumors exhibit distinct epidemiological, clinical, pathological, and molecular features depending on sm...
ORGANISM(S): Homo sapiens 
2014-10-30 | E-GEOD-62182 | biostudies-arrayexpress
ProteomicsHuman lung adenocarcinoma tissue LC-MS/MS
This project is a report of a chromosome-based human proteome project focused on chromosome 9 (Chr 9). To reveal missing proteins and undiscovered features in proteomes, LC-MS/MS analysis based identification and characterization were conducted on 5 pairs of lung adenocarcinoma tumors and adjacent n...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079961 | MassIVE
MetabolomicsA blood-based metabolic signature for earlier detection of lung cancer

Metabolomic profiling was applied to 1,259 sera collected within five years of a lung cancer diagnosis and 8,470 non-case sera from ever-smoker participants in the Prostate Lung Colorectal and Ovarian (PLCO) Study to identify metabolic signatures for the earlier detection of lung cancer. We devel...

2026-08-20 | MTBLS15406 | MetaboLights
ProteomicsLC7 Proteomic Analysis of Matched Control and NSCLC Lung Adenocarcinoma Tissue.
Non-small cell lung adenocarcinoma is the most frequently diagnosed lung cancer type and remains the leading cause of cancer mortality for men and women in the United States. Management of lung cancer is hindered by high false-positive rates due to the inability to resolve benign versus malignant tu...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-31 | MSV000080825 | MassIVE
TranscriptomicsSpheres culture from lung adenocarcinoma pleural effusions
Briefly, we analyzed gene expression profiles in adherent cultures compared to sphere cultures from malignant pleural effusions (MPEs). MPEs could represent an opportunity to culture a wide variety of cancer cells from different donors. In this study, we set up culture conditions for cancer cells de...
ORGANISM(S): Homo sapiens 
2011-12-02 | E-MEXP-3025 | biostudies-arrayexpress
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