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ProteomicsAcylated peptide enrichment utilizing lysine deacylases for lysine acylomics
Reversible acylation of lysine ε-amino groups, e.g., acetylation, succinylation, maronylation, and myristoylation, is involved in basic physiological processes such as metabolism, cell signaling and aging. In this study, we developed a novel enrichment method for acylated peptides without the use of...
ORGANISM(S): Homo Sapiens (human) 
PXD025845 | JPOST Repository
ProteomicsDe novo lysine myristoylation mediates synaptic plasticity and long-term potentiation through membrane association of synaptic proteins
Synaptic plasticity underlying long-term memory is associated with the generation of saturated free fatty acids (sFFAs), in particularly myristic acid, from membrane phospholipids via the phospholipase A1 isoform DDHD2. However, the mechanism through which myristic acid contributes to synaptic plast...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-22 | PXD061811 | Pride
Learning and memory. Synaptic plasticity Lipids  phospholipase a1  ddhd2  n-myristoyl transferase  myristic acid  lysine myristoylation 
ProteomicsCo-translational and Post-translational protein myristoylation in HeLa cells
Protein N-myristoylation is a ubiquitous co- and post-translational modification that has been implicated in the development and progression of a range of human diseases. In E. Thinon, R. A. Serwa, et al., Nature Communications 2014, doi:10.1038/ncomms5919, we report the global N-myristoylated prote...
ORGANISM(S): Homo sapiens (Human) 
2018-07-31 | PXD002687 | Pride
Co-translational modification Post-translational modification Apoptosis Protein myristoylation 
UnknownLysine myristoylation mediates long-term potentiation via membrane enrichment of synaptic plasticity effectors.
Not available
S-EPMC12316903 | biostudies-literature
UnknownThe role of lysine palmitoylation/myristoylation in the function of the TEAD transcription factors.
Not available
S-EPMC8942982 | biostudies-literature
UnknownMyristoylation of TMEM106B by NMT1/2 regulates TMEM106B trafficking and turnover.
Not available
S-EPMC12268641 | biostudies-literature
UnknownReversible lysine fatty acylation of an anchoring protein mediates adipocyte adrenergic signaling.
Not available
S-EPMC8851525 | biostudies-literature
UnknownLysine myristoylation mediates long-term potentiation via membrane enrichment of synaptic plasticity effectors
Not available
S-SCDT-10_1038-S44318-025-00484-3 | biostudies-other
UnknownHigh-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation.
Not available
S-EPMC7048800 | biostudies-literature
UnknownMUC1 drives ferroptosis resistance in ICC via Src-mediated FSP1 deubiquitination and myristoylation.
Not available
S-EPMC12510807 | biostudies-literature
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