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MetabolomicsInhibition of stress resilience and adult hippocampal neurogenesis by platelet-derived LPA16:0 in anxiety

Anxiety is an aggravating comorbidity of many psychiatric disorders that is often underdiagnosed and undertreated, and little is known on the mechanisms underlying its regulation. Here, we find that serum LPA16:0 abundance increases with trait anxiety in both humans and mice; while high LPA16:0 l...

2026-02-05 | MTBLS13589 | MetaboLights
MetabolomicsMulti-Omics profiling reveals immunometabolic adaptations underlying disease resilience in indigenous Lueyang Silky Fowl compared to White Leghorns
Sustainable avian production demands genetic strategies beyond vaccines to enhance disease resilience, particularly in indigenous breeds like Lueyang Silky Fowl (LSF), which show superior resistance compared to commercial White Leghorn chickens (WLC) but lack molecular characterization. We hypothesi...
2026-05-27 | MTBLS14590 | MetaboLights
MetabolomicsStability in metabolic phenotypes and inferred metagenome profiles before the onset of colitis-induced inflammation
Inflammatory bowel disease (IBD) is associated with altered microbiota composition and metabolism, but it is unclear whether these changes precede inflammation or are the result of it since current studies have mainly focused on changes after the onset of disease. We previously showed differences in...
2017-07-14 | MTBLS432 | MetaboLights
ProteomicsProteomic and Metabolomic study of the Quercus ilex response to Phytophthora cinnamomi, the main causal agent of the decline syndrome, and the identification of putative markers of resistance
Holm oak (Quercus ilex) is considered one of the major structural elements of the Mediterranean forests and the agrosilvopastoral Spanish “dehesa”, representing an outstanding example of ecological and socio-economic sustainability of forest ecosystems. The exotic pathogen Phytophthora cinnamomi is ...
ORGANISM(S): Quercus ilex (Holly oak) 
2024-05-21 | PXD046909 | Pride
Quercus ilex  decline syndrome  climate change  markers of resilience  proteomics  metabolomics 
GenomicsDecoding epigenetic markers: implications of traits and genes through DNA methylation in resilience and susceptibility to mastitis in dairy cows
Decoding epigenetic markers: implications of traits and genes through DNA methylation in resilience and susceptibility to mastitis in dairy cows
PRJNA1078401 | ENA
UnknownPersonality vulnerability to depression, resilience, and depressive symptoms: epigenetic markers among perinatal women.
Not available
S-EPMC11385460 | biostudies-literature
MetabolomicsDissecting Metabolism of Leaf Nodules in Ardisia crenata and Psychotria punctata
Root-microbe interaction and its specialized root nodule structures and functions are well studied. In contrast, leaf nodules harboring microbial endophytes in special glandular leaf structures have only recently gained increased interest as plant-microbe phyllosphere interactions. Here, we applied ...
2021-08-26 | MTBLS2870 | MetaboLights
MetabolomicsClustering of chemical profiles of Centella asiatica cultivars, grown in greenhouses, allows grouping of metabolites with similar production trends
Centella asiatica (L.) Urban (also known as ""gotu kola"") is a perennial plant, used in traditional medicine for promoting resilience to central nervous system (CNS) disorders. C. asiatica is a tropical medicinal herb from the Apiaceae family and is native to Southeast Asian countries. The chemical...
2026-10-21 | MTBLS11735 | MetaboLights
GenomicsTransthyretin orchestrates vitamin B12-induced stress resilience
Transthyretin orchestrates vitamin B12-induced stress resilience
PRJNA1109405 | ENA
UnknownBrain Markers of Resilience to Psychosis in High-Risk Individuals: A Systematic Review and Label-Based Meta-Analysis of Multimodal MRI Studies.
Not available
S-EPMC11939873 | biostudies-literature
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