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ProteomicsInhibitory effect of miR-183 on MCM family members
MYCN and HDAC2 jointly repress the transcription of tumor suppressive micro RNA miR-183 in neuroblastoma. Enforced miR-183 expression induces neuroblastoma cell death and inhibits anchorage-independent colony formation and subcutaneous xenograft growth in mice. We here aimed to unravel the miR-183 s...
ORGANISM(S): Homo sapiens (Human) 
2016-06-01 | PXD003596 | Pride
Label-free proteomics Cell cycle progression Eukaryotic genome replication Oncogene Genomic integrity 
UnknownGenome wide comparative comprehensive analysis of Plasmodium falciparum MCM family with human host.
Not available
S-EPMC3541329 | biostudies-literature
TranscriptomicsToll-like receptor 2 (TLR2)-TLR9 crosstalk dictates IL-12 family cytokine production in microglia
Microglia are the resident mononuclear phagocytes of the CNS parenchyma and represent an initial line of defense against invading microorganisms. Microglia utilize Toll-like receptors (TLRs) for pathogen recognition and TLR2 specifically senses conserved motifs of gram-positive bacteria including li...
ORGANISM(S): Mus musculus 
2014-12-22 | E-GEOD-24935 | biostudies-arrayexpress
UnknownExpression and Prognostic Value of MCM Family Genes in Osteosarcoma.
Not available
S-EPMC8257954 | biostudies-literature
TranscriptomicsGenome-wide transcriptome analyses of transgenic mice, that express Cre recombinase flanked by mutated estrogen receptors (MerCreMer; mcm), and carry loxP-flanked sequences of p53 and Mdm2 was performed in the presence and absence of Tamoxifen
Genome-wide transcriptome analyses of transgenic mice, that express Cre recombinase flanked by mutated estrogen receptors (MerCreMer; mcm), and carry loxP-flanked sequences of p53 and Mdm2 was performed in the presence and absence of Tamoxifen.
The molecular mechanisms underlying heart failure re...
ORGANISM(S): Mus musculus 
2017-02-23 | E-MTAB-5441 | biostudies-arrayexpress
UnknownIdentification and functional characterization of a new member of the human Mcm protein family: hMcm8.
Not available
S-EPMC140502 | biostudies-literature
UnknownMinichromosome Maintenance (MCM) Family as potential diagnostic and prognostic tumor markers for human gliomas.
Not available
S-EPMC4223428 | biostudies-literature
UnknownEukaryotic MCM proteins: beyond replication initiation.
Not available
S-EPMC362110 | biostudies-literature
TranscriptomicsMyotonic dystrophy type 1 (DM1) leads to altered mRNA expression in heart tissue
Myotonic dystrophy type 1 (DM1) is a dominantly inherited disease that affects multiple organ systems. Cardiac dysfunction is the second leading cause of death in DM1. We quantified gene expression in heart tissue from a heart-specific DM1 mouse model (EpA960/MCM) which inducibly expresses human DMP...
ORGANISM(S): Mus musculus 
2014-01-24 | E-GEOD-48991 | biostudies-arrayexpress
UnknownTAT-MTS-MCM fusion proteins reduce MMA levels and improve mitochondrial activity and liver function in MCM-deficient cells.
Not available
S-EPMC5824393 | biostudies-literature
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