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TranscriptomicsMajor Depressive Disorder blood gene expression
Background: Major Depressive Disorder (MDD) is a moderately heritable disorder with a high lifetime prevalence. At present, laboratory blood tests to support MDD diagnosis are not available. Methods: We used a classifier approach on blood gene expression profiles of a unique set of non-medicated su...
ORGANISM(S): Homo sapiens 
2011-10-04 | E-GEOD-19738 | biostudies-arrayexpress
TranscriptomicsHuman postmortem hippocampus: Major depressive disorder (MDD) vs. Control
We examined the genetic profile of postmortem brain (hippocampal) samples; 15 brains from patients diagnosed with MDD were matched to brains from healthy subjects based on gender, race and age. Gene expression profiles in the dentate gyrus and CA1 subregions of the hippocampus were assessed by cDNA...
ORGANISM(S): Homo sapiens 
2010-10-17 | E-GEOD-24095 | biostudies-arrayexpress
TranscriptomicsEpigenomics of rat born to dams fed a diet deficient in methyl group donors (MDD)
It is clearly established that the maternal diet during pregnancy can induce physiological and metabolic adaptations in the developing fetus which determine its susceptibility later in life to develop diabetes, obesity... The molecular and genomic mechanisms underlying the programming of the metabol...
ORGANISM(S): Rattus norvegicus 
2015-06-22 | E-GEOD-59191 | biostudies-arrayexpress
ProteomicsMass spectrometry analysis of MDD
Proteomics profiling of MDD plasma samples by mass spectrometry in DIA mode
ORGANISM(S): Homo Sapiens 
2024-06-22 | PXD053331 |
GenomicsWhole transcriptome sequencing of major depressive disorder (MDD) patients and healthy controls
Whole transcriptome sequencing of major depressive disorder (MDD) patients and healthy controls
PRJNA787461 | ENA
Methylation profilingMajor depression MDD suicide brain study
Background: Major Depressive Disorder (MDD) represents a major social and economic health issue and constitutes a major risk factor for MDD suicide. The molecular pathology of suicidal depression remains poorly understood, although it has been hypothesized that regulatory genomic processes are invol...
ORGANISM(S): Homo sapiens 
2016-11-01 | GSE88890 | GEO
GenomicsAnalysis of MDD and control patients by snRNA-seq
Analysis of MDD and control patients by snRNA-seq
PRJNA1093488 | ENA
TranscriptomicsExpression data from human brain anterior cingulate cortex - including control samples and samples with major depression disorders (26 samples BA25_F)
Major depressive disorder is a heterogeneous illness with a mostly uncharacterized pathology. Large scale gene expression (transcriptome) analysis and genome-wide association studies (GWAS) for single nucleotide polymorphisms have generated a considerable amount of gene- and disease-related informat...
ORGANISM(S): Homo sapiens 
2014-05-16 | E-GEOD-54571 | biostudies-arrayexpress
TranscriptomicsExpression data from human brain anterior cingulate cortex - including control samples and samples with major depression disorders (24 samples BA25_M)
Major depressive disorder is a heterogeneous illness with a mostly uncharacterized pathology. Large scale gene expression (transcriptome) analysis and genome-wide association studies (GWAS) for single nucleotide polymorphisms have generated a considerable amount of gene- and disease-related informat...
ORGANISM(S): Homo sapiens 
2014-05-16 | E-GEOD-54572 | biostudies-arrayexpress
TranscriptomicsGene Expression in Frontal Cortex in Major Depression and HIV
Major depressive disorder (MDD) is a clinically defined entity with little understanding as to the underlying pathological substrate. Biologically, MDD is characterized by disruption of neurotransmitters, especially serotonin and noradrenaline, which are the main targets of antidepressants. We pre...
ORGANISM(S): Homo sapiens 
2010-02-01 | E-GEOD-17440 | biostudies-arrayexpress
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