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ProteomicsStructure of an essential inner membrane protein-LPS complex identifies a novel anti-microbial peptide
Lipopolysaccharide (LPS) resides in the outer membrane (OM) of Gram-negative bacteria where it is responsible for barrier function and immune modulation. LPS is the target of polymyxins, last-resort antibiotics whose clinical use is threatened by increasing resistance. Steps in LPS biogenesis are ...
ORGANISM(S): Escherichia Coli K-12 (ncbitaxon:83333) 
2019-05-08 | MSV000083754 | MassIVE
TranscriptomicsIdentification of markers of responsiveness in rheumatoid arthritis patients
Despite the increasing of available drugs in RA, the overall rate of non response is 30 to 40% of treated patients. To optimize the drug prescription and better elaborate the therapeutic strategies, gene profiling in PBMCs was used to predict the responsiveness to anakinra. Thirty two patients treat...
ORGANISM(S): Homo sapiens 
2010-06-26 | E-GEOD-11827 | biostudies-arrayexpress
TranscriptomicsEarly and long-standing rheumatoid arthritis: molecular signatures identified by gene expression profiling in synovium
At a given time, rheumatoid arthritis (RA) is a heterogeneous disease and its underlying molecular mechanisms is still poorly understood. Because previous microarrays studies have only focused on late RA stages, we aimed to compare the biological and molecular profiles in early and long-standing (LS...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-13026 | biostudies-arrayexpress
UnknownCopying of Mixed-Sequence RNA Templates inside Model Protocells.
Not available
S-EPMC7547884 | biostudies-literature
UnknownStable Cellulose Nanofibril Microcapsules from Pickering Emulsion Templates.
Not available
S-EPMC9007535 | biostudies-literature
UnknownSupported bilayers with excess membrane reservoir: a template for reconstituting membrane budding and fission.
Not available
S-EPMC2905081 | biostudies-literature
ProteomicsVacuolar protein sorting-associated protein 1 (Vps1) has membrane constricting and severing abilities required for endosomal protein trafficking
Pathways that traffic proteins or cargo across organelles are fundamental to maintaining organelle identity and function. These pathways are largely conserved from yeast to humans. The retromer pathway traffics cargo from endosomes to the trans Golgi network (TGN). Defects in this pathway are linked...
ORGANISM(S): Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
2026-09-14 | PXD077915 | Pride
Lipids  membrane templates  membrane fission  fluorescence image analysis  endosome  vacuole  protein sorting  proteomics 
UnknownAnalyzing membrane remodeling and fission using supported bilayers with excess membrane reservoir.
Not available
S-EPMC4753780 | biostudies-literature
TranscriptomicsBIGenomics_Agilent_15k_templates
Hybridization of ligation probes to a zipcode (tag) microarray. The purpose of the experiment was to establish functionality and target specificity of the ligation probes by using pools of synthetic templates with all of the probes. The templates are 80-mer synthetic dsDNA molecules, each specific f...
ORGANISM(S): bioreactor metagenome 
2012-02-24 | E-MEXP-3538 | biostudies-arrayexpress
TranscriptomicsCharacterization of macrophage - cancer cell crosstalk in estrogen receptor positive and triple-negative breast cancer
We performed whole transcriptome sequencing of human monocytes that were co-cultured with estrogen receptor positive (ER+) or triple-negative (TNBC) breast cancer cell lines and studied the biological responses related to the differential gene activation in both cell types to understand how differen...
ORGANISM(S): Homo sapiens 
2015-11-19 | E-GEOD-75130 | biostudies-arrayexpress
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