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Mesothelin is a differentiation antigen expressed at high levels on the surface of many cancers; its interaction with cancer antigen CA-125 can lead to metastasis. Mesothelin has been the subject of intensive investigations as a potential cancer antigen for immunotherapy. Structures of a fragment of...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD034397 | Pride
Tear samples collected from patients with central retinal vein occlusion (n=58) and group of healthy volunteers (n=30) were analyzed using a proteomic label-free absolute quantitative ap-proach. We found a large proportion (458 proteins with a frequency > 0.6) of tear proteome shared between healthy...
ORGANISM(S): Homo sapiens (Human) 
2022-12-13 | PXD037021 | Pride
Mesothelin-induced lysosomal biogenesis sustains neutrophil longevity to drive brain metastasis
ZFP36 disruption is insufficient to enhance the function of mesothelin-targeting human CAR-T cells
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