Mesothelin - OmicsDI

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CHEBI ID

CHEBI:16628 (2)
CHEBI:17768 (2)
CHEBI:58148 (2)
CHEBI:70959 (2)
CHEBI:24149 (2)
CHEBI:89461 (2)
CHEBI:35704 (2)
CHEBI:17713 (2)
CHEBI:17172 (2)
CHEBI:16450 (2)
CHEBI:16675 (2)
CHEBI:28747 (2)
CHEBI:50129 (2)
CHEBI:60175 (2)
CHEBI:15611 (2)
CHEBI:17287 (2)
CHEBI:49033 (2)
CHEBI:15978 (2)
CHEBI:17677 (2)
CHEBI:184023 (2)
CHEBI:48928 (2)
CHEBI:17050 (2)
CHEBI:18295 (2)
CHEBI:18257 (2)
CHEBI:43580 (2)
CHEBI:15698 (2)
CHEBI:17140 (2)
CHEBI:17533 (2)
CHEBI:16708 (2)
CHEBI:17724 (2)

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3-hydroxyoleoylcarnitine (1)
3-hydroxypalmitoylcarnitine (1)
2-butenoylglycine (1)
Palmitoleoyl ethanolamide* (1)
Sphingomyelin (d18:2/18:1)* (1)

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2026 (10)
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Recruiting (2)
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Study type

Transcription profiling by array (11)
RNA-seq of coding RNA (11)
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RNA-seq of coding RNA from single cells (2)
Transcription profiling by SAGE (1)

Release Date

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2021 (44)
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2016 (30)
2019 (26)
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2017 (23)
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2009 (4)
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2004 (2)
2007 (1)
2003 (1)
2002 (1)
1999 (1)
1998 (1)

Lab affiliation

Associate Director of Analytical Services, Complex Carbohydrate Research Center, University of Georgia, Athens, Georgia, USA (1)
Biological Mass Spectrometry Lab Department of Translational Medicine (DiMeT) Center for Translational Research on Autoimmune & Allergic Diseases - CAAD University of Piemonte Orientale Corso Trieste 15/A, 28100, Novara, Italy (1)
Dr Ainhoa Mielgo, Tumour Microenvironment Lab, Department of Molecular and Clincial Cancer Medicine, University of Liverpool (1)
Institute of Biomedical Chemistry, 119121 Moscow, 10 Pogodinskaya str., bld. 8, Russian Federation; tel.: +7 495 246 16 41; web: www.ibmc.msk.ru (1)
Ist. G. Gaslini (1)
Nemours Children’s Hospital, DE (1)
Professor, Department of Obstetrics and Gynecology at Institute of Clinical Sciences, Kvinnokliniken SU Östra 416 85 Gothenburg, Sweden (1)
Systems Biology and Personalised Medicine, Walter & Eliza Hall Institute (1)
Technical Director Complex Carbohydrate Research Center 315 Riverbend Road Athens, Georgia 30602-4712 United States (1)
The Comprehensive Cancer Centre of Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, 321 Zhongshan Road, Nanjing, 210008, China. (1)

Location

China (2)
United States (2)

Keyword

CAR T cells (1)
CAR T cell (1)
Fludarabine (1)
Cyclophosphamide (1)
CAR T Cell (1)
Autologous (1)
T Cell (1)
Mesothelin (1)
MSLN (1)
HLA-A2 (1)
Solid Tumors expressing MSLN (1)
Pancreatic (1)
Cell Therapy (1)
Gene Therapy (1)
Blocker (1)
PANC (1)
OVCA (1)

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Structure of Cancer Antigen Mesothelin and Its Complex with Therapeutic Antibodies

Mesothelin is a differentiation antigen expressed at high levels on the surface of many cancers; its interaction with cancer antigen CA-125 can lead to metastasis. Mesothelin has been the subject of intensive investigations as a potential cancer antigen for immunotherapy. Structures of a fragment of...

ORGANISM(S): Homo sapiens (Human)

2023-05-10 | PXD034397 | Pride