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MetabolomicsStreamlined identification of strain engineering targets for bioprocess improvement using metabolic pathway enrichment analysis
Metabolomics is a powerful tool for the identification of genetic targets for bioprocess optimisation. However, in most cases, only the biosynthetic pathway directed to product formation is analysed, limiting the identification of these targets. Some studies have used untargeted metabolomics, allowi...
2023-08-31 | MTBLS6667 | MetaboLights
MetabolomicsMultitrait engineering of Hassawi red rice for sustainable cultivation
Sustainable agriculture requires locally adapted varieties that produce nutritious food with limited agricultural inputs. Genome engineering represents a viable approach to develop cultivars that fulfill these criteria. For example, the red Hassawi rice, a native landrace of Saudi Arabia, tolerates ...
2023-12-14 | MTBLS864 | MetaboLights
MetabolomicsEnzyme engineering for optimizing biosynthesis of 2,4-dihydroxybutyric acid via the synthetic threose-dependent glycolaldehyde assimilation (STEGA) pathway
Ethylene glycol is a potential feedstock for next-generation biorefineries, as it can be derived from both plastic waste and carbon dioxide. The synthetic D-threose-dependent glycolaldehyde assimilation (STEGA) pathway, which is orthogonal to central metabolism of Escherichia coli, was recently cons...
2026-07-15 | MTBLS15050 | MetaboLights
ModelsSmallbone2013 - Yeast metabolic model with linlog rate law
Kieran Smallbone & Pedro Mendes. Large-Scale Metabolic Models: From Reconstruction to Differential Equations. Industrial Biotechnology 9, 4 (2013). Genome-scale kinetic models of metabolism are important for rational design of the metabolic engineering required for industrial biotechnology applicat...
2024-09-02 | BIOMD0000000471 | BioModels
ModelsSmallbone2013 - Yeast metabolic model with modular rate law
Kieran Smallbone & Pedro Mendes. Large-Scale Metabolic Models: From Reconstruction to Differential Equations. Industrial Biotechnology 9, 4 (2013). Genome-scale kinetic models of metabolism are important for rational design of the metabolic engineering required for industrial biotechnology applicat...
2024-09-02 | BIOMD0000000472 | BioModels
ModelsSmallbone2013 - E.coli metabolic model with linlog rate law
Kieran Smallbone & Pedro Mendes. Large-Scale Metabolic Models: From Reconstruction to Differential Equations. Industrial Biotechnology 9, 4 (2013). Genome-scale kinetic models of metabolism are important for rational design of the metabolic engineering required for industrial biotechnology applicat...
2024-09-02 | BIOMD0000000469 | BioModels
ModelsSmallbone2013 - E.coli metabolic model with modular rate law
Kieran Smallbone & Pedro Mendes. Large-Scale Metabolic Models: From Reconstruction to Differential Equations. Industrial Biotechnology 9, 4 (2013). Genome-scale kinetic models of metabolism are important for rational design of the metabolic engineering required for industrial biotechnology applicat...
2024-09-02 | BIOMD0000000470 | BioModels
ModelsSmallbone2013 - Yeast metabolic model with modular rate law, merged with Pritchard 2002
Kieran Smallbone & Pedro Mendes. Large-Scale Metabolic Models: From Reconstruction to Differential Equations. Industrial Biotechnology 9, 4 (2013). Genome-scale kinetic models of metabolism are important for rational design of the metabolic engineering required for industrial biotechnology applicat...
2024-09-02 | BIOMD0000000473 | BioModels
TranscriptomicsRecovery of phenotypes obtained by adaptive evolution through inverse metabolic engineering
Reconstructed mutants of yeast by inverse metabolic engineering were characterized by fermentation physiology and tools from systems biology. Six reconstructed mutants of yeast were grown on aerobic batch with galactose as carbon source
ORGANISM(S): Saccharomyces cerevisiae 
2012-02-29 | E-GEOD-36118 | biostudies-arrayexpress
TranscriptomicsMetabolic and Transcriptional Reprogramming in Developing Soybean (Glycine max) Embryos
Soybean (Glycine max) seeds are an important source of seed storage compounds, including protein, oil, and sugar used for food, feed, chemical, and biofuel production. We assessed detailed temporal transcriptional and metabolic changes in developing soybean embryos to gain a systems biology view of ...
ORGANISM(S): Glycine max 
2013-12-13 | E-GEOD-46153 | biostudies-arrayexpress
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