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Purpose: We aimed to investigate in depth the regulation of microRNA expression by hypoxia in the breast cancer cell line MCF-7, establish the relationship between microRNA expression and HIF binding sites, pri-miRNA transcription and microRNA processing gene expression. Methods: microRNA sequencing...
ORGANISM(S): Homo sapiens 
Purpose: We aimed to investigate in depth the regulation of microRNA expression by hypoxia in the breast cancer cell line MCF-7, establish the relationship between microRNA expression and HIF binding sites, pri-miRNA transcription and microRNA processing gene expression. Methods: microRNA sequencing...
ORGANISM(S): Homo sapiens 
Purpose: We aimed to investigate in depth the regulation of microRNA expression by hypoxia in the breast cancer cell line MCF-7, establish the relationship between microRNA expression and HIF binding sites, pri-miRNA transcription and microRNA processing gene expression. Methods: microRNA sequencing...
ORGANISM(S): Homo sapiens 
The epidermal growth factor receptor (EGFR) is frequently overexpressed in cancer and is an important therapeutic target. Aberrant expression and function of microRNAs has been associated with tumorigenesis. Bioinformatic predictions suggest that the human EGFR mRNA 3’-untranslated region contains t...
ORGANISM(S): Homo sapiens 
MicroRNA are ~22nt-long small non-coding RNA that negatively regulate protein expression through mRNA degradation or translational repression in eukaryotic cells. Based upon their importance in regulating development and terminal differentiation in model systems, erythrocyte microRNA profiles were e...
ORGANISM(S): Human herpesvirus 4 
MicroRNA-7 regulates melanocortin circuits involved in mammalian energy homeostasis
The expression level of microRNA after knockdown of GATA3 in MCF-7 cells
This is the microRNA experiment from the study of ethanol effects on the cultured cell line MCF-7, which is derived from a human malignancy. Cells were cultured in 6 well plates for a period of 4 weeks in the presence or absence of 25 mM ethanol. Cells were washed once with phosphate buffered saline...
ORGANISM(S): Homo sapiens 
Transcriptome profiling of microRNA-mediated neuronal reprogramming with REST repression at day 7
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