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Ethanol exposure disrupts extraembryonic microtubule cytoskeleton and embryonic blastomere cell adhesion, producing epiboly and gastrulation defects

Gene expression was measured using microarrays in 8 hour postfertilization embryos, comparing control versus ethanol-treated (2 to 8 hours postfertilization) embryos. This experiment was performed to determine the gene expression changes that occur in response to ethanol treatment as a model of feta...

ORGANISM(S): Danio rerio

2014-07-09 | E-GEOD-48380 | biostudies-arrayexpress

Proteomic characterisation of microtubule-dependent modulation of adhesion complexes

Investigating the effect of microtubule disruption by nocodazole treatment on isolated adhesion complexes.

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-19 | MSV000079926 | MassIVE

Murine Embryonic Fibroblasts: Wild-type Stmn1 versus null Stmn1 Cells

Background: Stathmin (STMN1) protein functions to regulate assembly of the microtubule cytoskeleton by destabilizing microtubule polymers. Stathmin over-expression has been correlated with cancer stage progression, while stathmin depletion leads to death of some cancer cell lines in culture. In cont...

ORGANISM(S): Mus musculus

2009-07-31 | E-GEOD-17432 | biostudies-arrayexpress

A designed ankyrin repeat protein selected to bind to tubulin caps the microtubule plus end.

Not available

S-EPMC3409770 | biostudies-literature

Everolimus protects podocytes via stabilizing TUBB2B and DCDC2 expression

Glomerular podocytes are highly differentiated cells that are key components of the kidney filtration units. The podocyte cytoskeleton builds the basis for the dynamic podocyte cytoarchitecture and plays a central role for proper podocyte function. Recent studies implicate that immunosuppressive age...

ORGANISM(S): Homo sapiens

2015-09-09 | E-GEOD-66107 | biostudies-arrayexpress

Photoswitchable paclitaxel-based microtubule stabilisers allow optical control over the microtubule cytoskeleton.

Not available

S-EPMC7493900 | biostudies-literature

Macromolecular Crowding Tailors the Microtubule Cytoskeleton Through Tubulin Modifications and Microtubule-Associated Proteins.

Not available

S-EPMC10312695 | biostudies-literature

Photoswitchable Epothilone-Based Microtubule Stabilisers Allow GFP-Imaging-Compatible, Optical Control over the Microtubule Cytoskeleton.

Not available

S-EPMC9305116 | biostudies-literature

Fluorescent markers of the microtubule cytoskeleton in Zymoseptoria tritici.