monocyte-derived macrophages

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Transcriptomics (2861)
Unknown (2528)
Genomics (1435)
Proteomics (244)
Metabolomics (93)
Other (26)
Methylation profiling (6)
Multiomics (3)
Models (2)

Organisms

Mus musculus (1622)
Homo sapiens (1348)
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Mycobacterium tuberculosis (36)
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Francisella tularensis (12)
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Mycobacterium avium subsp. paratuberculosis K-10 (3)
Leishmania major (3)
Legionella pneumophila subsp. pneumophila str. Philadelphia 1 (2)
Brucella melitensis bv. 1 str. 16M (2)
Leishmania donovani (2)

Organisms

Homo sapiens (501)
Mus musculus (406)
Bos taurus (13)
Sus scrofa (8)
Rattus norvegicus (4)
Mycobacterium tuberculosis (3)
Gallus gallus (2)
Equus caballus (2)
Canis lupus familiaris (2)
Danio rerio (2)
Legionella pneumophila subsp. pneumophila str. Philadelphia 1 (1)
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Nothobranchius furzeri (1)
Mycobacterium avium subsp. hominissuis (1)
Mesocricetus auratus (1)
Mus (1)
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Mus musculus musculus (1)
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Repository

biostudies-arrayexpress (2246)
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pride (82)
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PanoramaPublic (5)
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BioModels (1)
Cell Collective (1)
MetabolomicsWorkbench (1)

Tissue

Macrophage (43)
Blood (18)
Cell culture (17)
Monocyte (15)
Bone marrow (6)
Primary cell (5)
Liver (4)
Blood cell (3)
Dendritic cell (2)
Hepatocyte (2)
Osteoclast (2)
Macrophages (1)
Ascites (1)
Blood plasma (1)
Blood serum (1)
Brain (1)
CD14-positive monocyte (1)
Cell lysate (1)
Chest muscle (1)
Embryonic stem cell (1)
Endometrial gland (1)
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Endothelial cell of hepatic sinusoid (1)
Endothelial cell of umbilical vein (1)
Epithelial cell (1)
Femur (1)
HiPSC cell (1)
Lung (1)
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M2 macrophage (1)

Disease

Normal (9)
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Disease free (4)
Human immunodeficiency virus infectious disease (4)
Influenza (3)
Malignant neoplasm of ovary (3)
COVID-19 (2)
Tumor bearing (1)
Pulmonary arterial hypertension (1)
HIV encephalitis (1)
Yersinia enterocolitica WAP infected (virulent) (1)
HIV-associated dementia (1)
Moderate (1)
Schizophrenia (1)
Mild asthma (1)
No tendon xanthomas (1)
Rheumatoid arthritis (1)
HIV-Tuberculosis with Immune Reconstitution Inflammatory Syndrome (1)
Leukemia (1)
SS2-infected (1)
Viral myocarditis (1)
Infected with Leishmania amazonensis (1)
Obesity (1)
C. burnetii infected (1)
Acute promyelocytic leukemia (1)
VSV infection (1)
Adenocarcinoma (1)
Multiple myeloma (1)
Control (1)
Acute leukemia (1)

Technology Type

Mass Spectrometry (83)
Mass spectrometry (58)
Shotgun proteomics (38)
Mass spectrometry assay (33)
Bottom-up proteomics (18)
Data-dependent acquisition (13)
Data-independent acquisition (9)
Gel-based experiment (9)
SWATH MS (7)
Affinity purification coupled with mass spectrometry proteomics (5)
ILLUMINA, Illumina HiSeq 2000 (3)
Illumina HiSeq 2000 (3)
DiaPASEF (3)
Illumina HiSeq 2000, ILLUMINA (2)
Chemical cross-linking coupled with mass spectrometry proteomics (2)
ILLUMINA, NextSeq 500 (1)
Illumina HiSeq 2500, ILLUMINA (1)
Illumina HiSeq 2000, NextSeq 500, ILLUMINA (1)
Illumina Human Custom 1, Illumina Human-Ref-8 v3 beadchip, 2M and Human 610 Quad Custom arrays (1)
Illumina MiSeq (1)
NMR spectroscopy assay (1)
ESI (1)
Affinity proteomics (1)
All-ion fragmentation (1)
Glycoproteomics (1)
SRM/MRM (1)
Top-down proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (73)
NextSeq 500 (46)
Illumina HiSeq 2000 (42)
Illumina HiSeq 4000 (39)
Illumina HiSeq 2500 (28)
Illumina HiSeq 1500 (20)
NextSeq 550 (18)
NextSeq 2000 (11)
Illumina NovaSeq X (10)
BD Rhapsody (3)
10x Genomics Chromium (3)
G2565AA DNA microarray scanner [Agilent] (3)
Illumina Genome Analyzer II (3)
NA (3)
DNBSEQ-G400 (3)
HiSeq X Ten (3)
Not applicable (2)
Generation III Array Scanner [Amersham] (2)
Bioanalyser (2)
418 [Affymetrix] (2)
GenePix 4000B [Axon Instruments] (2)
N/A (2)
Illumina HiSeq 1000 (2)
Illumina MiSeq (2)
Illumina HiSeq 3000 (2)
NanoDrop 2000 spectrophotometer (1)
DNBelab C Series High-throughput Single-cell RNA Library Preparation Set V3.0 (MGI Tech) (1)
DNBelab C-TaiM droplet generator (MGI Tech) (1)
Avatarget 12-well dual-chamber organ-on-chip system; AvatarFlow Organ Chip Flow Initiation Controller System (Avatarget Co., Ltd., Suzhou, China) (1)
Digital Alliance of Canada (1)

Publication Date

2014 (270)
2015 (263)
2013 (249)
2010 (238)
2025 (235)
2026 (230)
2012 (223)
2011 (194)
2016 (189)
2024 (178)
2008 (161)
2023 (149)
2022 (141)
2021 (124)
2020 (119)
2009 (116)
2019 (79)
2007 (79)
2018 (64)
2017 (63)
2006 (24)
2005 (10)
2004 (8)
2003 (6)

UNIPROT ID/AC

5DNU_SALTY (1)
6PGD_SALTY (1)
6PGL_SALTY (1)
99287.STM2621 (1)
99287.STM2628 (1)
99287.STM2632 (1)
99287.STM3813 (1)
99287.STM3814 (1)
99287.STM3815 (1)
99287.STM4146 (1)
AAC6_SALTY (1)
AAS_SALTY (1)
AAT_SALTY (1)
ABDH_SALTY (1)
ACCA_BORPE (1)
ACCA_SALTY (1)
ACCD_SALTY (1)
ACEA_SALTY (1)
ACEK_SALTY (1)
ACKA_SALTY (1)
ACNA_SALTY (1)
ACNB_SALTY (1)
ACP_BORPE (1)
ACP_SALTY (1)
ACSA_SALTY (1)
ACYP_SALTY (1)
ADD_SALTY (1)
AGAL_SALTY (1)
AGP_SALTY (1)
AHPC_SALTY (1)

CHEBI ID

CHEBI:17596 (20)
CHEBI:16708 (19)
CHEBI:16919 (18)
CHEBI:15891 (17)
CHEBI:16027 (17)
CHEBI:16335 (17)
CHEBI:17368 (17)
CHEBI:32816 (16)
CHEBI:30915 (16)
CHEBI:16737 (16)
CHEBI:30769 (16)
CHEBI:15741 (15)
CHEBI:16750 (15)
CHEBI:18012 (15)
CHEBI:17562 (15)
CHEBI:16704 (14)
CHEBI:17858 (14)
CHEBI:16856 (13)
CHEBI:16015 (13)
CHEBI:17822 (12)
CHEBI:17509 (12)
CHEBI:17361 (12)
CHEBI:17568 (12)
CHEBI:16264 (12)
CHEBI:16467 (12)
CHEBI:16235 (12)
CHEBI:15428 (12)
CHEBI:15603 (12)
CHEBI:48928 (11)
CHEBI:28044 (11)

Metabolite Name

Hypoxanthine (23)
Creatinine (21)
Adenine (19)
Creatine (19)
Uracil (17)
Betaine (16)
Ornithine (16)
Choline (16)
Adenosine (16)
Cytosine (16)
Taurine (15)
Inosine (15)
L-Tryptophan (14)
Uric acid (14)
Cytidine (14)
Guanosine (14)
Indole (13)
Xanthine (13)
L-Tyrosine (13)
5-Aminopentanoic acid (12)
Thymine (12)
Pyridoxine (12)
Guanine (12)
L-Phenylalanine (12)
Histidine (11)
Glycine (11)
Thiamine (11)
Pantothenic acid (11)
Citric acid (11)
Arginine (11)

First Public Date

2025 (154)
2026 (142)
2024 (135)
2023 (117)
2014 (98)
2022 (95)
2021 (75)
2020 (71)
2019 (45)
2017 (43)
2018 (32)
2015 (24)
2016 (21)
2013 (8)

Modelling Approach

Ordinary differential equation model (1)

Lab affiliation

Infectious Diseases and Immunity in Global Health Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada (2)
School of Medicine, University College Dublin, Belfield, Dublin 4, Ireland (2)
University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry (2)
Assistant Professor Department of Cellular and Molecular Medicine Florida International University | Herbert Wertheim College of Medicine (1)
Associate Professor Translational Health Science and Technology Institute NCR Biotech Science Cluster 3rd Milestone,Gurugram-Faridabad Expressway Faridabad-121001 (1)
Associate professor at Macquarie University, Sydney, Australia Visiting professor at Institute for Glyco-core Research (iGCORE), Nagoya Univeristy, Aichi, Japan (1)
CABIMER (1)
CABIMER-University of Sevilla (1)
CIR, Queen’s Medical Research Institute, University of Edinburgh (1)
Cell Signalling and Immunology Division, School of Life Sciences, University of Dundee (1)
Cellular and Molecular Immunology Research Unit (CMIRU), Faculty of Allied Health Science, Naresuan University, Phitsanulok, Thailand (1)
Center for Tumor Biology and Immunology (ZTI), Philipps University, Hans-Meerwein-Strasse 3, 35043 Marburg, Germany (1)
Core Facility - High-Throughput Mass Spectrometry, Charité -Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health (BIH), Berlin, Germany (1)
Department for Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology, Hans Knöll Institute Jena, Germany (1)
Department of Anatomy and Cell Biology, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA, USA (1)
Department of Anesthesiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China (1)
Department of Biochemistry and Chemistry, Centre for Cardiovascular Biology and Disease Research, La Trobe Institute for Molecular Science, School of Agriculture, Biomedicine and Environment, La Trobe University, Bundoora, Victoria 3086, Australia (1)
Department of Biochemistry and Chemistry, Research Centre for Extracellular Vesicles, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC 3086, Australia (1)
Department of Biological Engineering, MIT, Cambridge, USA Ragon Institute of Mass General, Harvard, and MIT, Cambridge, USA (1)
Department of Biology, University of Crete, Heraklion, Crete, Greece; Institute of Molecular Biology and Biotechnology, Foundation for Research and Technology-Hellas, GR70013, Heraklion, Crete, Greece (1)
Department of Biomolecular Sciences University of Urbino "Carlo Bo" Campus Scientifico Enrico Mattei, Via Cà le Suore, 2 61029 Urbino (PU) ITALY (1)
Department of Dermatology and Venereology, University of Cologne, Faculty of Medicine, and University Hospital of Cologne; Cologne, Germany Center of Molecular Medicine Cologne (CMMC), University of Cologne; Cologne, Germany (1)
Department of Medicine, Center for Interdisciplinary Cardiovascular Sciences, Division of Cardiovascular Medicine, Brigham Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA (1)
Department of Molecular Systems Biology, Helmholtz Centre for Environmental Research - UFZ,Leipzig, Germany (1)
Department of Molecular and Applied Microbiology, Leibniz Institute for Natural Product Research and Infection Biology - Hans Knöll Institute Jena (Leibniz-HKI) (1)
Department of Molecular and Cellular Hemostasis, Sanquin Research, Amsterdam, the Netherlands; 3Department of Biomolecular Mass Spectrometry and Proteomics, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands (1)
Department of Obstetrics and Gynecology, School of Medicine, Stanford University, CA, USA. Igenomix Foundation, Instituto de Investigación Sanitaria Hospital Clínico (INCLIVA), Valencia, Spain (1)
Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, 985800 University of Nebraska Medical Center, Omaha, NE 68198-5800, USA (1)
Dept. of Biochemistry and Molecular Biology, University of Southern Denmark, Campusvej 55, 5230 Odense M, Denmark. (1)
Dept. of Medicine III, University Hospital Aachen, Aachen, Germany (1)

IsPrivate

False (1)

Classification

bacteria (6)

Study type

Transcription profiling by array (1542)
RNA-seq of coding RNA (305)
ChIP-seq (105)
RNA-seq of coding RNA from single cells (60)
Unknown experiment type (48)
RNA-seq of total RNA (21)
RNA-seq of non coding RNA (21)
Transcription profiling by RT-PCR (18)
Other (16)
Methylation profiling by array (10)
Human - High-throughput sequencing (7)
Cell line - High-throughput sequencing (6)
Comparative genomic hybridization by array (6)
Methylation profiling by high throughput sequencing (6)
Transcription profiling by SAGE (5)
Animal - High-throughput sequencing (5)
ATAC-seq (5)
Proteomic profiling by array (5)
Human - One-color microarray (4)
MicroRNA profiling by array (4)
DNA-seq (4)
ChIP-chip by tiling array (3)
One-color microarray (3)
High-throughput sequencing (3)
Transcription profiling by tiling array (3)
MicroRNA profiling by high throughput sequencing (3)
Cell line - Single-cell sequencing (2)
Animal - One-color microarray (2)
Genotyping by array (2)
Spatial transcriptomics by high-throughput sequencing (2)

Release Date

2014 (331)
2015 (329)
2022 (307)
2016 (303)
2023 (295)
2021 (285)
2013 (279)
2012 (276)
2025 (270)
2010 (269)
2024 (266)
2020 (243)
2011 (235)
2019 (187)
2018 (182)
2008 (169)
2017 (159)
2009 (136)
2026 (93)
2007 (82)
2006 (31)
2005 (12)
2004 (9)
2003 (9)
2002 (7)
2000 (4)
2001 (3)
1999 (1)
1998 (1)
1997 (1)

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Inhibition of Peripheral Serotonin Activates Hepatic AMPK and Reduces Monocyte-Derived Liver Macrophages, Ameliorating Obesity-Associated Fibrosis

Monocyte-derived liver macrophages are critical in the pathogenesis of metabolic dysfunction-associated steatohepatitis (MASH) and liver fibrosis, but their recruitment mechanisms remain unclear. Serotonin (5-hydroxytryptamine, 5HT) is a conserved monoamine synthesized by tryptophan hydroxylase (Tph...

ORGANISM(S): Mus musculus

2025-10-30 | E-MTAB-15760 | biostudies-arrayexpress

microRNA profiling of human monocytes and monocyte-derived macrophages

microRNA profiling data includes biological replicates of primary monocytes and macrophages from three human donors Dye swap hybridization arrays were performed for total RNA isolated from fresh monocytes and 7-day monocyte-derived macrophages from each of three human donors

ORGANISM(S): Homo sapiens

2013-05-10 | E-GEOD-39905 | biostudies-arrayexpress

Sublytic membrane attack complex drives glycolysis and mitochondrial dysfunction with inflammatory consequences in human monocyte-derived macrophages

Not available

ORGANISM(S): Homo sapiens

ST001922 | MetabolomicsWorkbench

Transcription profiling of human peripheral blood monocyte (MONO), human peripheral blood monocyte derived macrophages treated with M-CSF (MACRO)and primary alveolar macrophages (BAL)

In order to study the gene expression profiles of monocyte and macrophages, we collected three type of cells and performed pair-wised comparison. It includes human peripheral blood monocyte (MONO), human peripheral blood monocyte derived macrophages treated with M-CSF (MACRO)and primary alveolar mac...

ORGANISM(S): Homo sapiens

2006-12-01 | E-MEXP-524 | biostudies-arrayexpress

The cellular and proteomic response of primary and immortalized murine Kupffer cells following immune stimulation diverges from that of monocyte-derived macrophages

Kupffer cells are the first line of defense in the liver against pathogens, yet several microbes successfully target the liver, bypass immune surveillance, and effectively develop in this tissue. Our current, albeit poor, understanding of Kupffer cell-pathogen interactions has been largely achieved ...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-22 | MSV000079995 | MassIVE

Transcriptome profile of human dermal macrophages and monocyte-derived macrophages

DC, monocyte and macrophage networks are evolutionarily conserved but the distinct subsets have been difficult to distinguish due to shared overlapping phenotypic markers between the cells. Using transcriptome microarray profiling of human and mouse mononuclear phagocyte subsets, we have distinguish...

ORGANISM(S): Homo sapiens

2014-10-15 | E-GEOD-60317 | biostudies-arrayexpress

Infiltrating monocyte-derived macrophages and resident kupffer cells display different ontogeny and functions in acute liver injury

Molecular profiling of infiltrating monocyte-derived macrophages versus resident kupffer cells following acute liver injury The liver has a remarkable capacity to regenerate after injury; yet, the role of macrophages (MF) in this process remains controversial mainly due to difficulties in distinguis...

ORGANISM(S): Mus musculus

2014-08-01 | E-GEOD-55606 | biostudies-arrayexpress

Transcription profiling of human monocyte derived macrophages reveals induction of dendritic cell-like phenotype in macrophages during foam cell formation

Foam cell formation from monocyte-derived macrophages is a hallmark of atheroscle-rotic lesions. Aspects of this process can be recapitulated in vitro by exposing MCSF-induced or platelet factor4 (CXCL4)-induced macrophages to oxidized (ox) or minimally modified (mm) low density lipoprotein (LDL). W...

ORGANISM(S): Homo sapiens

2008-06-15 | E-GEOD-7138 | biostudies-arrayexpress

CXCL4 induces a unique transcriptome in monocyte-derived macrophages

Human blood monocytes were differentiated over six days with either 100 ng/ml M-CSF or 1 umol/l CXCL4 In atherosclerotic arteries, blood monocytes differentiate to macrophages in the presence of growth factors like macrophage colony-stimulation factor (MCSF) and chemokines like platelet factor 4 (CX...

ORGANISM(S): Homo sapiens

2010-03-07 | E-GEOD-20484 | biostudies-arrayexpress

Transcriptional responses of human monocyte-derived macrophages (HMDM) to lipopolysaccharide (LPS) - Illumina arrays

These microarrays were performed for use in a genome-wide scan for LPS-regulated genes in human monocyte-derived macrophages, in order to construct a list of LPS-regulated genes for detailed interrogation on custom microarrays (see GSE19482 for custom array analysis). Human monocyte-derived macropha...

ORGANISM(S): Homo sapiens

2012-03-28 | E-GEOD-19765 | biostudies-arrayexpress

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