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ProteomicsLabel free quantitative (LFQ) proteomic analysis of mouse lymphatic endothelial cells and primary mouse dendritic cells in response to IFNgamma treatment in presence or absence of 3-HKA
To explore the cellular pathways and the molecular functions affected by a novel biogenic amine, (3-HKA), we performed a label free quantitative (LFQ) proteomic analysis of mouse lymphatic endothelial cells (LEC), and primary dendritic cells, treated with IFNgammaplus or minus 3-HKA. Biological tri...
ORGANISM(S): Mus musculus (Mouse) 
2021-07-28 | PXD015865 | Pride
Mouse lymphatic endotehlial cells (lec)  mouse primary dendritic cells (pdc)  nanolc-ms/ms 
TranscriptomicsMicroRNA profiling of mouse conventional dendritic cells, plasmacytoid dentritic cells and CD4 T cells
MicroRNA profiling of mouse murine pDC and cDC dendritic cell subsets obtained from Flt3L/SCF-supplemented bone marrow cultures
ORGANISM(S): Mus musculus 
2010-09-10 | E-MTAB-186 | biostudies-arrayexpress
GenomicsMtg16 regulates E protein activity and lineage specification in dendritic cell development (ChIP-seq)
E protein transcription factors specify major immune cell lineages including lymphocytes and interferon-producing plasmacytoid dendritic cells (pDCs). Corepressors of the ETO family can bind to and block transactivation by E proteins, but the physiological role of these interactions remained unclear...
ORGANISM(S): Homo sapiens 
2014-06-13 | E-GEOD-43876 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human and mouse dendritic cell subsets
Dendritic cells (DCs) are a complex group of cells which play a critical role in vertebrate immunity. Spleen or lymph node resident DCs are subdivided into conventional DC (cDC) subsets (CD11b and CD8alpha in mouse; BDCA1 and BDCA3 in man) and plasmacytoid DCs (pDCs). It is currently unclear if thes...
ORGANISM(S): Mus musculus 
2008-06-16 | E-GEOD-9810 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of thymocyte differentiation in knockout mouse models
Microarray experiment with whole thymi from genetically enginereed mice, with purified thymocyte samples and with cell lines.
ORGANISM(S): Mus musculus 
2004-06-30 | E-MEXP-96 | biostudies-arrayexpress
MetabolomicsMitochondrial KMT9 methylates DLAT to control pyruvate dehydrogenase activity and prostate cancer growth

Prostate cancer (PCa) growth depends on de novo lipogenesis controlled by the mitochondrial pyruvate dehydrogenase complex (PDC). In this study, we identified lysine methyltransferase (KMT)9 as a novel regulator of PDC activity. KMT9 is localized in mitochondria of PCa cells, but not in mitochond...

2024-12-10 | MTBLS2452 | MetaboLights
TranscriptomicsReal-time quantitative PCR analysis of mRNA from lungs of WT and Pglyrp1-/- mice sensitized with HDM
Wild type (WT) and Pglyrp1-/- mice were treated with PBS or sensitized 5 days/week for 3 or 5 weeks with 10 M-BM-5l per application of 2.5 mg/ml of purified house dust mite allergen. 3 days after the last sensitization the lungs were removed and homogenized, and RNA was isolated from the right lobes...
ORGANISM(S): Mus musculus 
2012-12-25 | E-GEOD-43137 | biostudies-arrayexpress
TranscriptomicsRestricted Dendritic Cell and Monocyte Progenitors in Human Cord Blood and Bone Marrow
In mice, two restricted DC progenitors, macrophage-dendritic progenitor (MDP) and common dendritic cell progenitor (CDP) demonstrate increasing commitment of DC lineage as they sequentially lose granulocyte and monocyte potential respectively. Identifying these progenitors has enabled understanding ...
ORGANISM(S): Homo sapiens 
2015-01-22 | E-GEOD-65128 | biostudies-arrayexpress
UnknownCytokine-driven loss of plasmacytoid dendritic cell function in chronic lymphocytic leukemia.
Not available
S-EPMC4100939 | biostudies-literature
TranscriptomicsmicroRNA expression profiling of various C57Bl/6 myeloid cell populations
microRNAs are assumed to fine-tune cellular mRNA expression levels predisposing them for the control of cell development and cell fates. However, despite increasing appreciation of the role of miRNAs in controlling myeloid cell functions and some evidence for their contribution in in vitro monocyte ...
ORGANISM(S): Mus musculus 
2012-11-22 | E-GEOD-42434 | biostudies-arrayexpress
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