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TranscriptomicsAdipocyte Differentiation of Immortalized Human Bone Marrow-derived Stromal Cells is Modulated by microRNA-155, microRNA-221 and microRNA-222
Human bone marrow mesenchymal stromal cells are capable of limited self-renewal and multi-lineage differentiation in vitro. Several studies have demonstrated that microRNAs, post-transcriptional modifiers of protein expression, play crucial roles in the regulation of these complex processes. To gain...
ORGANISM(S): Homo sapiens 
2011-08-22 | E-GEOD-24898 | biostudies-arrayexpress
ProteomicsUncovering the secretome of mesenchymal stromal cells exposed to healthy, traumatic and 1 degenerative intervertebral discs: A proteomic analysis
Mesenchymal stromal cells (MSCs) have been introduced as promising cell source for regenerative medicine. Besides their multilineage differentiation capacity, MSCs release a wide spectrum of bioactive factors. This secretome holds immunomodulatory and regenerative capacities. In intervertebral disc ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD021281 | Pride
Human Lc-ms Mesenchymal stromal cells Ms1 quantification 
UnknownMultilineage Differentiation Potential of Equine Adipose-Derived Stromal/Stem Cells from Different Sources.
Not available
S-EPMC10135324 | biostudies-literature
TranscriptomicsTranscription profiling of Mesenchymal stem cells (MSC) maintained in FCS vs autologous serum analysed at passage 4
The purpose of this study was to determine whether the serum condition affected the gene expression in mesenchymal stem cells (MSCs). To that end, we compared gene expression in MSCs maintained in regular growth medium supplemented with fetal calf serum (FCS) with gene expression of MSCs cultured in...
ORGANISM(S): Homo sapiens 
2004-12-08 | E-MEXP-214 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mesenchymal stem cells (MSC) maintained in FCS or autologous serum over time analysed at passage 4 and 10
The purpose of this study was to determine whether the serum condition affected the gene expression in mesenchymal stem cells (MSCs)over time. To that end, we compared gene expression in MSCs maintained in regular growth medium supplemented with fetal calf serum (FCS) for 10 passages with gene expre...
ORGANISM(S): Homo sapiens 
2004-12-08 | E-MEXP-215 | biostudies-arrayexpress
UnknownMUSE Stem Cells Can Be Isolated from Stromal Compartment of Mouse Bone Marrow, Adipose Tissue, and Ear Connective Tissue: A Comparative Study of Their In Vitro Properties.
Not available
S-EPMC8065981 | biostudies-literature
TranscriptomicsComparative gene expression analysis of mesenchymal stem cells (MSC) derived from non-small cell lung cancer (NSCLC) and corresponding normal lung tissue (NLT)
The stromal microenvironment plays a vital role in cancer initiation and progression. We performed a comparative expression profiling of pulmonary MSC derived from NSCLC and corresponding normal lung tissue of 5 newly diagnosed patients. The analysis indicated variable expression of genes involved i...
ORGANISM(S): Homo sapiens 
2013-02-07 | E-GEOD-23066 | biostudies-arrayexpress
TranscriptomicsDifferential expression of mouse Grem1+ Vs. Grem1- bone-marrow cells
The gene expression of bone marrow cells of mice enriched for Gremlin1 vs control was measured (n=3). It is not known if endogenous adult mesenchymal stem cells (MSCs) exist.Following culture,perisinusoidal mesenchymal cells can clonally recapitulate the skeletal microenvironment, but this fails to ...
ORGANISM(S): Mus musculus 
2015-02-10 | E-GEOD-57729 | biostudies-arrayexpress
UnknownMeflin defines mesenchymal stem cells and/or their early progenitors with multilineage differentiation capacity.
Not available
S-EPMC8360184 | biostudies-literature
TranscriptomicsscRNA-seq of Multi-lineage differentiating Stress Enduring (Muse) cell and non-Muse cells isolated from bone marrow-derived mesenchymal stem cells
MSCs comprise several percent of pluripotent-like cells named Multilineage-differentiating stress enduring (Muse) cells that express pluripotent markers at moderate levels, are collectable as cells positive for the pluripotent surface marker SSEA-3, are able to differentiate into triploblastic linea...
ORGANISM(S): Homo sapiens 
2022-10-26 | E-MTAB-10854 | biostudies-arrayexpress
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