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To identify germ cell- and somatic cell-specific gene expression profiles, we performed expression microarray analysis of the mouse gonads of the Nanos3+/-, Nanos3-/- female and male embryos from E12.5 to E15.5. Biological duplicates were examined at each stage, genotype, and sex for each experiment...
ORGANISM(S): Mus musculus 
Post-transcriptional RNA regulation is critical for the formation of primordial follicles, which determine female reproductive potential. Stress-induced disruptions in RNA metabolism are increasingly recognized as key factors impairing oogenesis, but the underlying mechanisms remain poorly understoo...
ORGANISM(S): Mus musculus (Mouse) 
2026-09-07 | PXD058281 | Pride
Human embryonic stem cells (cell line HS401) were transfected with piggyBac over expression constructs for germ cell specific RNA binding proteins, Nanos homolog 3 (NANOS3) or Deleted in azoospermia-like (DAZL). Cells transfected with a construct without open reading frame (MOCK), were used as contr...
ORGANISM(S): Homo sapiens 
scRNA-Seq of bovine fetal testes derived from NANOS3 knockout and wildtype embryos
To identify germ cell- and somatic cell-specific gene expression profiles, we performed expression microarray analysis of the mouse gonads of the Nanos3+/-, Nanos3-/- female and male embryos from E12.5 to E15.5.
ORGANISM(S): Mus musculus 
2013-02-06 | GSE38297 | GEO
We performed single cell RNA-sequencing (scRNA-Seq) of testes from bovine fetuses derived from either CRISPR/Cas9 NANOS3 knockout (KO; NANOS3 -/-) or wildtype control (NANOS3 +/+) embryos. The scRNA-Seq analysis showed a complete loss of primordial germ cells (PGCs) and gonocytes in NANOS3 KO fetal ...
ORGANISM(S): Bos taurus 
2023-11-15 | GSE244321 | GEO
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