Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of skeletal muscle from wild type and Nebulin knock-out mice
Knock out of the Nebulin gene. We compared the Quadriceps of two Nebulin -deficient vs. 2 Wildtype mice. The two KO-WT pairs derived from two litters (F2 generation, background: C57/Bl6 and 129/IB10).
ORGANISM(S): Mus musculus 
2006-11-01 | E-MEXP-733 | biostudies-arrayexpress
TranscriptomicsGenome-wide gene expression analysis on tibialis anterior muscle from nebulin SH3 domain deleted (Neb∆SH3) mice
Genome-wide gene expression analysis on tibialis anterior muscle from 2-month-old nebulin SH3 domain deleted (Neb∆SH3) mice compared to wildtype. Total RNA was obtained from biological triplicates of tibialis anterior muscle from 2-month-old nebulin SH3 domain deleted (Neb∆SH3) mice compared to wild...
ORGANISM(S): Mus musculus 
2013-09-23 | E-GEOD-47801 | biostudies-arrayexpress
TranscriptomicsThe effect of Nebulin-Deficiency on Skeletal Muscle
Nebulin is a giant filamentous protein that is coextensive with the actin filaments of the skeletal muscle sarcomere. Nebulin mutations are the main cause of nemaline myopathy (NEM), with typical NEM adult patients having low expression of nebulin, yet the roles of nebulin in adult muscle remain po...
ORGANISM(S): Mus musculus 
2015-06-25 | E-GEOD-70213 | biostudies-arrayexpress
TranscriptomicsThe effect of Nebulin-Deficiency on Skeletal Muscle
Nebulin is a giant filamentous protein that is coextensive with the actin filaments of the skeletal muscle sarcomere. Nebulin mutations are the main cause of nemaline myopathy (NEM), with typical NEM adult patients having low expression of nebulin, yet the roles of nebulin in adult muscle remain poo...
ORGANISM(S): Mus musculus 
2015-06-25 | GSE70213 | GEO
TranscriptomicsIn vivo and in vitro investigations of heterozygous nebulin knock-out mice reveal similarities with mild human form of nemaline myopathy [mRNA]
In the present study, we used a multimodal approach including protein and gene expression analysis and combined in vivo and in vitro measurements of force production. Overall, we aimed at investigating the functional impact of the expression of a single nebulin allele. Comparison of the mRNA express...
ORGANISM(S): Mus musculus 
2012-09-01 | E-GEOD-36743 | biostudies-arrayexpress
TranscriptomicsIn vivo and in vitro investigations of heterozygous nebulin knock-out mice reveal similarities with mild human form of nemaline myopathy [miRNA]
In the present study, we used a multimodal approach including protein and gene expression analysis and combined in vivo and in vitro measurements of force production. Overall, we aimed at investigating the functional impact of the expression of a single nebulin allele. Comparison of the miRNA expres...
ORGANISM(S): Mus musculus 
2012-09-01 | E-GEOD-36741 | biostudies-arrayexpress
TranscriptomicsIn vivo and in vitro investigations of heterozygous nebulin knock-out mice reveal similarities with mild human form of nemaline myopathy
This SuperSeries is composed of the following subset Series: GSE36741: In vivo and in vitro investigations of heterozygous nebulin knock-out mice reveal similarities with mild human form of nemaline myopathy [miRNA] GSE36743: In vivo and in vitro investigations of heterozygous nebulin knock-out mice...
ORGANISM(S): Mus musculus 
2012-09-01 | E-GEOD-36745 | biostudies-arrayexpress
UnknownExpressing a Z-disk nebulin fragment in nebulin-deficient mouse muscle: effects on muscle structure and function.
Not available
S-EPMC6986074 | biostudies-literature
UnknownNebulin regulates actin filament lengths by a stabilization mechanism.
Not available
S-EPMC2878950 | biostudies-literature
UnknownNebulin binding impedes mutant desmin filament assembly.
Not available
S-EPMC3681697 | biostudies-literature
Sort   by:  
 Page size