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GenomicsAn increase in ROS is required for repair of the neonatal cerebellum
An increase in ROS is required for repair of the neonatal cerebellum
PRJNA1121249 | ENA
TranscriptomicsExpression of Cell Cycle related genes in developing mouse cerebellum
The goal of the study was to analize expression of cell cycle related genes during postnatal development of Ts65Dn (Down syndrome mouse model) and control mice cerebellum. Keywords: Gene expression study in mouse model of disease RNA from 3 controls and 3 Ts65Dn postnatal day 2 cerebellum were anali...
ORGANISM(S): Mus musculus 
2008-05-18 | E-GEOD-9216 | biostudies-arrayexpress
TranscriptomicsGene expression signature of cerebellum hypoplasia in a mouse model of Down syndrome (Part I).
We designed a large scale gene expression study in Ts1Cje mice between P0 and P10 in order to measure the effects of trisomy 21 on a large number of samples (56 in total) in a tissue that is affected in Down syndrome (the cerebellum) and to quantify the defect during development in order to correlat...
ORGANISM(S): Mus musculus 
2009-03-31 | E-GEOD-11448 | biostudies-arrayexpress
UnknownAn increase in reactive oxygen species underlies neonatal cerebellum repair.
Not available
S-EPMC11507802 | biostudies-literature
ProteomicsRADIATION-INDUCED MODIFICATIONS IN MICRO-RNA AND PROTEOMIC CARGO IN PLASMA-DERIVED EXTRACELLULAR VESICLES
In this study, to delineate the radiation-induced changes in miRNAs and protein cargo, we established the microRNA and proteome profiles of plasma EVs collected from mice that had been sham- (SI), whole body (WBI), or partial body irradiated (PBI) with 2 Gy X-rays 24 hours before. The radiation-indu...
ORGANISM(S): Mus musculus (Mouse) 
2022-03-10 | PXD026408 | Pride
Proteomics Radiation  ionizing radiation  neonatal cerebellum  apoptosis Mirnome 
TranscriptomicsTranscription profiling by array of mouse Ts1Cje (mouse model of Down syndrome) and euploids murine cerebellum during postnatal development
Transcriptome analysis of Ts1Cje (mouse model of Down syndrome) and euploids murine cerebellum during postnatal development Keywords = Down syndrome Keywords = Chromosome 21 Keywords = Transcriptome Keywords = Microarray Keywords = Cerebellum Keywords = Development Keywords: other
ORGANISM(S): Mus musculus 
2004-12-05 | E-GEOD-1611 | biostudies-arrayexpress
GenomicsAn increase in ROS is required for repair of the neonatal cerebellum
The neonatal mouse cerebellum shows remarkable regenerative potential upon injury at birth. Nestin-expressing progenitors (NEPs) undergo adaptive reprogramming to replenish the lost granule cell progenitors. Here, we investigate how the injury microenvironment affects NEPs’ regenerative potential an...
ORGANISM(S): Mus musculus 
2024-12-05 | GSE269342 | GEO
UnknownLipopolysaccharide-Induced Systemic Inflammation in the Neonatal Period Increases Microglial Density and Oxidative Stress in the Cerebellum of Adult Rats.
Not available
S-EPMC7283979 | biostudies-literature
UnknownThe Circadian Oscillator of the Cerebellum: Triiodothyronine Regulates Clock Gene Expression in Granule Cells in vitro and in the Cerebellum of Neonatal Rats in vivo.
Not available
S-EPMC8578874 | biostudies-literature
UnknownThe Transcription Factor, α1ACT, Acts Through a MicroRNA Network to Regulate Neurogenesis and Cell Death During Neonatal Cerebellar Development.
Not available
S-EPMC10307715 | biostudies-literature
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