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Analysis of microarray data from fetal pancreatic cells 24 hr after exposure to Netrin-4 revealed changes in the expression of several genes relevant to cell cycle control, and differentiation and development.
ORGANISM(S): Homo sapiens 
The generation of induced pluripotent stem (iPS) cells holds great promise in regenerative medicine. However, the relative flaws in the understanding of the molecular mechanisms promoting or limiting reprogramming still hinder the efficient generation of high quality iPS cells. Whereas modulation o...
ORGANISM(S): Mus musculus 
Floor plate-derived extracellular signaling molecules, including canonical axon guidance cues of the Netrin family, control neuronal circuit organization. Despite the importance of the floor plate as an essential signaling centre in the developing vertebrate central nervous system, no systematic app...
ORGANISM(S): Danio rerio 
Netrin-1 signalling function in mouse pluripotent stem cells [ChIP-Seq]
Targeting netrin-1 in established atherosclerosis promotes inflammation resolution and plaque regression
Here we report the derivation of human embryonic stem cells (hESC-) derived FP tissue capable of secreting Netrin-1 and SHH and patterning primary and hESC derived tissues. Three replicate plates of human embryonic stem cells (A-C) were differentiated to various days (D#) using Noggin+SB431542 with ...
ORGANISM(S): Homo sapiens 
Pharmacological targeting Netrin-1 inhibits EMT in cancer [Visium]
Pharmacological targeting Netrin-1 inhibits EMT in cancer [BulkRNA-seq]
Netrin-1 blockade induces tumor growth inhibition and EMT reversion in endometrial cancer [Mouse_Pten]
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