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Obesity-driven phosphatidylethanolamine dysregulation impairs neuroimmune crosstalk and accelerates Alzheimer's pathogenesis
Background: Trigeminal neuralgia (TN) is a debilitating neuropathic pain disorder with a higher prevalence in females, yet its pathogenic mechanisms and underlying sexual dimorphism remain incompletely understood. Phosphorylation modifications are critical regulators of pain signaling, but comprehen...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-02-26 | PXD066745 | Pride
IL-17RC signaling connects intestinal microbiota and neuroimmune interactions in atherosclerosis
While dysbiosis and inflammation were previously implicated in cardiovascular diseases, the circuits of how microbiota drives distant perivascular innervation, neuroinflammation, and atherosclerosis remains unknown. Here, we report that IL-17RC signaling in the intestine protects from atherosclerosi...
ORGANISM(S): Mus musculus 
2026-03-11 | GSE322757 | GEO
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