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TranscriptomicsMetastable pluripotent states in NOD mouse derived ES cells
Embryonic stem (ES) cells are isolated from the inner cell mass (ICM) of developing blastocysts, whereas epiblast stem cells (EpiSCs) are derived from the post-implantation epiblast and are characterized by a restricted developmental potential. Although certain mouse strains, such as the non-obese d...
ORGANISM(S): Mus musculus 
2009-04-09 | E-GEOD-15603 | biostudies-arrayexpress
TranscriptomicsTranscriptomic response to Nod Factor treatments on Medicago
NGS2013-04: Transcriptomic response to Nod Factor treatments on Medicago Role of the root hair in water and nutrient uptake and the establishment of the nitrogen-fixing symbiotic interaction with rhizobia. The RNA was extracted from root hairs of Medicago: control vs treated by nod factors (2 biolog...
ORGANISM(S): Medicago truncatula 
2016-06-01 | E-GEOD-67921 | biostudies-arrayexpress
TranscriptomicsStrigolactone biosynthesis requires the symbiotic GRAS-type transcription factors NSP1 and NSP2
Legume GRAS-type transcription factors NSP1 and NSP2 are essential for Rhizobium Nod factor-induced nodulation. Both proteins are considered to be Nod factor response factors regulating gene expression upon symbiotic signalling. However, legume NSP1 and NSP2 can be functionally replaced by non-legum...
ORGANISM(S): Medicago truncatula 
2011-11-01 | E-GEOD-26548 | biostudies-arrayexpress
TranscriptomicsExpression data from NOD and C57BL/6 mouse pancreas CD8α- Dendritic Cells (DCs) under steady-state and after in-vitro LPS stimulation
Abstract Two major dendritic cell (DC) subsets have been described in the islets of mice: The immunogenic CD8α-CD11b+ DCs and the tolerogenic CD8α+CD103+ DCs. We have recently reported on reduced numbers of the minor population of tolerogenic CD8α+CD103+ DCs in the pancreas of 5 week old pre-dia...
ORGANISM(S): Mus musculus 
2014-07-01 | E-GEOD-45028 | biostudies-arrayexpress
TranscriptomicsTranscriptome and Molecular Pathways Analysis of CD4 T-Cells from Young NOD Mice
Type 1 diabetes is a multigenic disease caused by T-cell mediated destruction of the insulin producing β-cells. Although conventional (targeted) approaches of identifying causative genes have advanced our knowledge of this disease, many questions remain unanswered. Using a whole molecular systems st...
ORGANISM(S): Mus musculus 
2014-06-20 | E-GEOD-46600 | biostudies-arrayexpress
no omics definedTranscription profiling of Medicago truncatula treated with Sinorhizobium meliloti Nodulation factors at 6 and 48 h time points
This experiment studies the effect of purified Sinorhizobium meliloti Nodulation factors (Nod-factors, NF) on gene expression in the model legume Medicago truncatula.
ORGANISM(S): Medicago truncatula 
2007-03-31 | E-MEXP-943 | biostudies-arrayexpress
ProteomicsRhizobial Nod factors modulate reactive oxygen species, jasmonates, and pattern-recognizing receptors to suppress immune response
Fine-tuning of the immune response plays a key role in legume-rhizobial symbiosis. Rhizobial Nod factors can suppress the defense responses during symbiosis, but the possible mechanisms of such regulation remain poorly understood. Here, we observe that Nod factors effectively suppress the expression...
ORGANISM(S): Pisum sativum (Garden pea) 
2026-07-10 | PXD069618 | Pride
Legume-rhizobial symbiosis  immune response regulation  nod factors  reactive oxygen species  jasmonic acid  pattern-recognizing receptors  pisum sativum l.  medicago truncatula gaerth 
TranscriptomicsDifferential gene expression in the Lacrimal gland during development and onset of xerostomia in Sjogren's syndrome-like disease of the C57BL/6.NOD-Aec1Aec2 mouse.
Recently, we reported the development of the C57BL/6.NOD-Aec1Aec2 mouse that carries two genetic intervals derived from the NOD mouse capable of conferring Sjogren's syndrome (SjS)-like disease in SjS-non-susceptible C57BL/6 mice. In an attempt to define the molecular bases underlying onset of stoma...
ORGANISM(S): Mus musculus 
2013-06-25 | E-GEOD-48139 | biostudies-arrayexpress
TranscriptomicsGene expression data from Medicago truncatula plantlet roots treated with symbiotic lipochitooligosaccharides (LCOs).
Legumes interact with soil microbes, leading to the development of nitrogen-fixing root nodules and arbuscular mycorrhizal (AM) roots. While nodule initiation by diffusible lipochitooligosaccharide (LCO) Nod-factors of bacterial origin (Nod-LCOs) is well characterized, diffusible AM fungal signals w...
ORGANISM(S): Medicago truncatula 
2012-05-30 | E-GEOD-33636 | biostudies-arrayexpress
OtherType 1 Diabetes Prone NOD Mice Have Diminished Cxcr1 mRNA Expression in Polymorphonuclear Neutrophils and CD4+ T Lymphocytes.
Data from ProteomeXchange, PXD ID: PXD003015. File: OB07268.mzml. Published as part of PLoS One. 2015 Jul 31;10(7):e0134365 . From the Abstract: {{i}} ... Here, we report descriptive data about the Cxcr1 gene in NOD mice ... {{/i}}
ORGANISM(S): Mus_musculus_viruses, Mouse 
GPM32310024995 | GPMDB
Resource Reanalysis 
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