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The goal of this project is to profile the composition of the extracellular matrix (ECM) of healthy human omentum and mesentery, the two primary sites of high-grade serous ovarian cancer metastasis.
ORGANISM(S): Homo sapiens (Human) 
2025-11-26 | PXD061586 | Pride
High-grade serous (HGS) ovarian cancer is the most common and aggressive ovarian cancer type, and the most lethal gynaecological disease 1,2. The major cause is its highly metastatic nature and the limited availability of effective therapies to oppose it. The omentum is a highly vascularised viscera...
ORGANISM(S): Homo sapiens (Human) 
2023-11-28 | PXD042317 | Pride
High-grade serous (HGS) ovarian cancer is the most common and aggressive ovarian cancer type, and the most lethal gynaecological disease 1,2. The major cause is its highly metastatic nature and the limited availability of effective therapies to oppose it. The omentum is a highly vascularised viscera...
ORGANISM(S): Homo sapiens (Human) 
2023-11-28 | PXD042320 | Pride
High-grade serous (HGS) ovarian cancer is the most lethal gynaecological disease in the world and metastases is a major cause. The omentum is the preferential metastatic site in HGS ovarian cancer patients and in vitro models that recapitulate the original environment of this organ at cellular and m...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-28 | PXD045024 | Pride
BMDMs were stimulated with ATRA and/or omentum culture supernatant and gene expression was determined by Illumina microarray 8 BMDM Samples
ORGANISM(S): Mus musculus 
RNA-seq analysis of macrophages from normal and tumor-infiltrated omentum
Sequencing of mRNA from tissue-resident and tumor-associated macrophages in murine omentum display distinct transcriptional profile between macrophage subset of different origin
ORGANISM(S): Mus musculus 
Tregs recruited to the omentum and spleen express distinct transcriptomes
Single cell RNA sequencing of macrophages harvested from omentum of mice 10 weeks after intra peritoneal inoculation of epithelial ovarian cancer cells.
ORGANISM(S): Mus musculus 
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