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ProteomicsDivide-and-conquer matrisome protein (DC-MaP) strategy: an optimal approach to proteomic matrisome characterization
Currently, the extracellular matrix (ECM) is considered a pivotal complex meshwork of macromolecules playing a plethora of biomolecular functions in health and disease beyond its commonly known mechanical role. Only by unravelling its composition, we can leverage related tissue engineering and pharm...
ORGANISM(S): Homo sapiens (Human) 
2020-12-03 | PXD020823 | Pride
Proteins Identifcation Matrisome Fractionation Human Ovarian 
ProteomicsMouse PSC Q-regulated matrisome
The goal of this project was to assess how glutamine availability regulates the matrisome. ECM deposited by pancreatic stellate cells (PSCs) in the presence of TGFb stimulation under 4, 1, or 0.4mM glutamine (Q) was profiled.
ORGANISM(S): Mus musculus (Mouse) 
2026-04-19 | PXD073686 | Pride
Ecm Psc Matrisome Fibroblast Glutamine 
ProteomicsChemical and Random Additive Noise Elimination (CRANE) - Case Study - Matrisome Dataset
The effectiveness of the novel electrospray ionisation - liquid chromatography mass spectrometry (ESI-LC-MS) data de-noising technique, CRANE, is demonstrated by denoising the MS1 and all the MS2 windows of a matrisome, data-independent acquisi-tion (DIA) MS dataset from Krasny, et al. (2018).
ORGANISM(S): Mus musculus (Mouse) 
2021-07-26 | PXD025103 | Pride
Lc-msms Random noise Chemical noise Baseline noise Dia 
ProteomicsTemporal Profiling of PyMT Tumour Matrisome during Progression
In this study, through coupling of our ISDoT tissue decellularisation technology with quantitative mass spectrometry, we explored the changing tumour matrisome during mammary tumourigenesis in the PyMT breast cancer model compared to age-matched healthy control mammary gland
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2022-03-30 | MSV000089167 | MassIVE
ProteomicsProteomic analysis of matrisome proteins from laser capture microdissected FFPE tissue slides of HnSCC xenograft
Liquid chromatography mass spectrometry was used to study tumor matrisome from laser capture microdissected FFPE tissue sections of human neck and squamous cell carcinoma (HnSCC) xenograft grown in mouse.
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2023-10-21 | PXD033023 | Pride
Tumor matrisome Xenograft Laser capture microdissection 
ProteomicsThe matrisome: in silico definition and in vivo characterization of tumor extracellular matrix
Naba A, Clauser KR, Hoersch S, Liu H, Carr SA, Hynes RO. Mol Cell Proteomics 2012, 11: M111.014647. doi:10.1074/mcp.M111.014647. PMCID:PMC3322572. Tranche_hash:onoKvMCC9umP0dW2GlZSGN/DVfz6tqoyRvsA16h351RjGJZiqjk0wWGYQB9+zPpRj+ASAgKsd779N0Td4250FCPJ6jUAAAAAAABFoQ==
2013-11-20 | MSV000078494 | MassIVE
GenomicsEducation of tumour-associated macrophages by the tumour matrisome inhibits immune surveillance
Education of tumour-associated macrophages by the tumour matrisome inhibits immune surveillance
PRJNA772736 | ENA
ProteomicsMatrisome Proteomics Reveals Novel Mediators of Muscle Remodeling with Aerobic Exercise Training
Skeletal muscle has a unique ability to remodel in response to stimuli such as contraction and aerobic exercise training. Phenotypic changes in muscle that occur with training such as a switch to a more oxidative fiber type, and increased capillary density contribute to the well-known health benefit...
ORGANISM(S): Mus musculus (Mouse) 
2024-07-30 | PXD053003 | Pride
Matrisome-associated Proteomics Skeletal muscle Remodeling Exercise Core matrisome 
UnknownMatrisome changes in Parkinson's disease.
Not available
S-EPMC8944212 | biostudies-literature
ProteomicsProteome-wide and matrisome-specific atlas of the human ovary from prepuberty to menopause
Our modern era is witnessing an increasing infertility rate worldwide. Although some of the causes can be attributed to our modern lifestyle (eg. persistent organic polluants, late pregnancy), our knowledge of the human ovarian tissue has remained limited and insufficient to reverse the infertility ...
ORGANISM(S): Homo sapiens (Human) 
2022-04-06 | PXD025940 | Pride
Human ovary Matrisome Reproduction 
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