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Infections by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ranging from the initial Wildtype (WT) variant in Wuhan, China, to later variants including Omicron, have showcased a diverse spectrum of symptoms. This diversity underscores the need for ongoing exploration into the vir...
2025-02-28 | MTBLS12231 | MetaboLights
The Omicron variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first identified in November 2021 in South Africa, has initiated the 5th wave of global pandemics. Here, we systemically examined immunological and metabolic characteristics of Omicron variants infection. We found ...
ORGANISM(S): Cercopithecus aethiops (Green monkey) (Grivet) 
2023-03-11 | PXD037955 | Pride
During V(D)J recombination antibody diversity is enhanced by non-templated junctional modifications that generate immensely diverse heavy chain (HC) and light chain (LC) complementarity-determining 3 antigen-contact regions (CDR3s). We previously developed a mouse model that generates diverse antibo...
ORGANISM(S): Mus musculus 
RBD protein from the SARS-CoV-2 omicron variant (RBDom) was produced in Komagataella phaffii. Peptide mapping and intact mass analysis of RBDom were performed by LC/MS. Proteins were identified using BioPharma Finder software.
ORGANISM(S): Komagataella Phaffii 
This study aimed to understand the host response to Omicron infections by performing metabolomic profiling of plasma.
ORGANISM(S): Homo Sapiens 
2023-02-24 | PXD040370 |
The ancestral SARS-CoV-2 strain that initiated the Covid-19 pandemic at the end of 2019 has rapidly mutated into multiple variants of concern with variable pathogenicity and increasing immune escape strategies. However, differences in host cellular antiviral responses upon infection with SARS-CoV-2 ...
ORGANISM(S): Homo sapiens (Human) 
2023-05-10 | PXD037265 | Pride
We applied a 4D dia-PASEF proteomic approach to investigate the salivary protein profile of individuals with early-to-acute SARS-CoV-2 Omicron infection. We combined proteomics and functional analyses with feature selection and ROC multivariate analysis to identify and assess salivary proteins for C...
ORGANISM(S): Homo sapiens (Human) 
2025-01-18 | PXD054133 | Pride
Detection of high level of co-infection and the emergence of novel SARS-CoV-2 delta-omicron and omicron-omicron recombinants in the epidemiological surveillance of Andalusia (Spain)
Here, we systematically profiled clinical phenomes, transcriptomes, proteomes, metabolomes, and immune repertoire of blood cells or plasma in over 1000 specimens from SARS-CoV-2 Omicron patients across multiple disease phases.
ORGANISM(S): Homo Sapiens 
Infections by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), ranging from the initial Wildtype (WT) variant in Wuhan, China, to later variants including Omicron, have showcased a diverse spectrum of symptoms. This diversity underscores the need for ongoing exploration into the vir...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD054443 | Pride
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