Sort   by:  
 Page size 
TranscriptomicsGene expression analysis of Ox40-cre/ROSA-YFP CD4+ T cell subsets
An Ox40-cre allele was used for lineage marking of CD4 T cells. Naive T cells that had previously expressed OX40 demonstrated a partially activated phenotype that was distinct from that of the majority of naive T cells. These results are consistent with a minor subpopulation of naive T cells being...
ORGANISM(S): Mus musculus 
2010-04-03 | E-GEOD-13502 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of OX40-triggered mouse Treg
Regulatory T (Treg) maintain the tumor microenvironment in an immunosuppressive state preventing effective anti-tumor immune response. A possible strategy to overcome Treg cell suppression focuses on OX40, a costimulatory molecule expressed constitutively by Treg cells while induced in activated eff...
ORGANISM(S): Mus musculus 
2011-09-25 | E-GEOD-32373 | biostudies-arrayexpress
ProteomicsAnalysis of GITR and OX40 signaling complexes
T cells are pivotal in the adaptive immune defense, necessitating a delicate balance between robust response against infections and self-tolerance. Their activation involves intricate cross-talk among signaling pathways triggered by the T-cell antigen receptors (TCR) and co-stimulatory or inhibitory...
ORGANISM(S): Mus musculus (Mouse) 
2024-04-25 | PXD046422 | Pride
T cells  co-stimulation  gitr  ox40  abin1  ms 
UnknownOX40/OX40 ligand and its role in precision immune oncology.
Not available
S-EPMC11300540 | biostudies-literature
GenomicsOX40 mediates crosstalk between innate and adaptive immunity and promotes nonalcoholic steatohepatitis development
OX40 mediates crosstalk between innate and adaptive immunity and promotes nonalcoholic steatohepatitis development
PRJNA415058 | ENA
UnknownA novel anti-OX40 human monoclonal antibody that blocks OX40/OX40L signaling and depletes OX40<sup>+</sup> T cells.
Not available
S-EPMC12102438 | biostudies-literature
UnknownSmall-molecule modulators of the OX40-OX40 ligand co-stimulatory protein-protein interaction.
Not available
S-EPMC4294117 | biostudies-literature
UnknownGeneration and characterization of OX40-ligand fusion protein that agonizes OX40 on T-Lymphocytes.
Not available
S-EPMC11757143 | biostudies-literature
GenomicsOX40 regulates double-negative regulatory T cells dependently of its effects on conversion and function
OX40 regulates double-negative regulatory T cells dependently of its effects on conversion and function
PRJNA421906 | ENA
TranscriptomicsGene expression analysis of OX40+ Tregs from human liver tissues
Analysis of the gene signature of OX40+ Tregs, in comparison to OX40- Tregs and Tconvs, freshly isolated from liver cirrhosis and tumor of chronic HCV patients. Results provide insights into the metabolic mechanisms of Treg proliferation in premalignant/malignant contexts.
ORGANISM(S): Homo sapiens 
2018-06-26 | GSE103523 | GEO
Sort   by:  
 Page size