pancreatic ductal adenocarcinoma

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Unknown (6747)
Genomics (2010)
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Genomic (3)

Organisms

Homo sapiens (1159)
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synthetic construct (13)
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mouse gut metagenome (1)
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blank sample (1)
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Organisms

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Mus musculus (514)
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mouse gut metagenome (1)
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MetabolomicsWorkbench (1)

Tissue

Pancreas (49)
Liver (7)
Lung (5)
Blood (3)
Colon (3)
Adrenal gland (2)
Brain (2)
Breast (2)
Esophagus (2)
Kidney (2)
Ovary (2)
Prostate gland (2)
Stomach (2)
Testis (2)
Urinary bladder (2)
Uterine cervix (2)
Uterus (2)
Bile duct (1)
Bone (1)
Bone marrow (1)
Bone tissue (1)
Caecum (1)
Cartilage tissue (1)
Chordate pharynx (1)
Connective tissue (1)
Gall bladder (1)
Hematopoietic system (1)
Ileum (1)
Large intestine (1)
Lymph node (1)

Disease

Pancreatic ductal adenocarcinoma (88)
Pancreatic carcinoma (8)
Normal (7)
Non-small cell lung carcinoma (4)
Acute myeloid leukemia (3)
Breast adenocarcinoma (3)
Breast carcinoma (3)
Cervical squamous cell carcinoma (3)
Chondrosarcoma (3)
Chronic myelogenous leukemia (3)
Diffuse large B-cell lymphoma (3)
Gastric adenocarcinoma (3)
Hepatocellular carcinoma (3)
Large cell lung carcinoma (3)
Lung adenocarcinoma (3)
Melanoma (3)
Mesothelioma (3)
Multiple myeloma (3)
Neuroblastoma (3)
Osteosarcoma (3)
Ovarian adenocarcinoma (3)
Ovarian carcinoma (3)
Pancreatic adenocarcinoma (3)
Renal cell carcinoma (3)
Rhabdomyosarcoma (3)
Small cell lung carcinoma (3)
Squamous cell lung carcinoma (3)
Askin tumor (2)
B-cell acute lymphoblastic leukemia (2)
Burkitts lymphoma (2)

Technology Type

Mass Spectrometry (216)
Shotgun proteomics (110)
Bottom-up proteomics (51)
Data-dependent acquisition (27)
Affinity purification coupled with mass spectrometry proteomics (20)
Data-independent acquisition (18)
SWATH MS (13)
Mass spectrometry (10)
Gel-based experiment (8)
SRM/MRM (6)
Mass spectrometry assay (4)
All-ion fragmentation (3)
Immunopeptidomics (3)
Top-down proteomics (3)
DiaPASEF (2)
AB SOLiD 4 System, Illumina HiSeq 2500, Illumina HiSeq 2000, AB SOLiD System 3.0 (1)
HiSeq X Ten, Illumina HiSeq 4000, Illumina HiSeq 2500, ILLUMINA (1)
ILLUMINA, Illumina HiSeq 2500, HiSeq X Ten (1)
Illumina HiSeq 2500, Illumina HiSeq 2000 (1)
Illumina_450K (1)
Nanostring cancer pathway, Nanostring Cancer Immune, ILLUMINA, Affymetrix GeneChipÂ® Human Transcriptome Array 2.0, Illumina HiSeq 4000 (1)
NMR (1)
Chemical cross-linking coupled with mass spectrometry proteomics (1)
HDMSE (1)
MSE (1)
Proteogenomics (1)

Instrument Platform

Illumina NovaSeq 6000 (11)
Q Exactive (9)
Illumina HiSeq 2500 (8)
Illumina HiSeq 2000 (7)
Orbitrap Fusion Lumos (7)
NextSeq 550 (6)
NextSeq 500 (5)
Illumina HiSeq 4000 (4)
Illumina NovaSeq X (3)
Q-Exactive (2)
Shimadzu Nexera LC-30AD UHPLC system (2)
NextSeq 550 (Illumina). (1)
Agilent TapeStation (1)
Agilent Bioanalyzer 2100 (or TapeStation); Qubit 4 Fluorometer (Thermo Fisher Scientific) (1)
NanoDrop ND-1000 spectrophotometer (1)
BD Rhapsody Sequence Analysis Pipeline (1)
Aurora Cytek Cs 5L (1)
Whole Transcriptome v2 kit (1)
BD Rhapsody (1)
Linux server (GPU/CPU cluster) (1)
Biological safety cabinet, centrifuge, 40 µm strainer (1)
Standard cell culture setup (1)
Cell culture incubator (37 °C, 5 % CO₂) (1)
Element AVITI (1)
Illumina iScan-Scanner (1)
454 GS 20 (1)
Illumina Genome Analyzer IIx (1)
Axon- GenePix4000B (1)
None (1)
DNBSEQ-G400 (1)

Publication Date

2026 (299)
2025 (295)
2024 (230)
2023 (175)
2022 (126)
2020 (98)
2021 (97)
2015 (61)
2016 (60)
2019 (53)
2017 (47)
2014 (47)
2018 (44)
2013 (44)
2012 (37)
2011 (26)
2010 (25)
2009 (9)
2008 (7)
2007 (4)
2006 (1)

CHEBI ID

CHEBI:15354 (4)
CHEBI:16393 (3)
CHEBI:16750 (3)
CHEBI:16828 (3)
CHEBI:16856 (3)
CHEBI:16919 (3)
CHEBI:17295 (3)
CHEBI:17368 (3)
CHEBI:17596 (3)
CHEBI:17895 (3)
CHEBI:24813 (3)
CHEBI:28946 (3)
CHEBI:116314 (2)
CHEBI:133185 (2)
CHEBI:142440 (2)
CHEBI:143243 (2)
CHEBI:15355 (2)
CHEBI:15428 (2)
CHEBI:15676 (2)
CHEBI:15724 (2)
CHEBI:15727 (2)
CHEBI:15756 (2)
CHEBI:15760 (2)
CHEBI:15891 (2)
CHEBI:15901 (2)
CHEBI:15918 (2)
CHEBI:15956 (2)
CHEBI:16020 (2)
CHEBI:16040 (2)
CHEBI:16163 (2)

Metabolite Name

Choline (4)
Beta-Alanine (3)
Creatine (3)
Glycerophosphocholine (3)
Glycine (3)
Hypoxanthine (3)
L-Tryptophan (3)
L-Tyrosine (3)
1-Methylhistidine (2)
5-Hydroxy-tryptophan (2)
5-Hydroxylysine (2)
Acetylcarnitine (2)
Alanine (2)
Anserine (2)
Arginine (2)
Carnitine (2)
Glutarylcarnitine (2)
Histidine (2)
Homoserine (2)
L-Arginine (2)
L-Methionine (2)
L-Phenylalanine (2)
L-Threonine (2)
Lactate (2)
Norvaline (2)
Pyridoxine (2)
S-(1,2-dicarboxyethyl)glutathione (2)
Sarcosine (2)
Serine (2)
Tyramine (2)

First Public Date

2026 (292)
2025 (281)
2024 (237)
2023 (170)
2022 (115)
2020 (107)
2021 (80)
2014 (70)
2019 (62)
2017 (45)
2018 (41)
2015 (25)
2016 (20)
2013 (8)

Modification

2x(15)N labeled L-lysine (2)
4x(15)N labeled L-arginine (2)

Study status

Recruiting (23)
Active, not recruiting (7)
Completed (5)
Terminated (4)
Not provided (3)
Not yet recruiting (1)
Ongoing (1)
Withdrawn (1)

Study type

Transcription profiling by array (135)
Interventional (41)
RNA-seq of coding RNA (36)
Comparative genomic hybridization by array (31)
ChIP-seq (11)
RNA-seq of coding RNA from single cells (9)
Methylation profiling by array (6)
Observational (4)
Cell line - High-throughput sequencing (3)
Genotyping by array (3)
RNA-seq of non coding RNA (3)
Transcription profiling by RT-PCR (2)
DNA-seq (2)
Unknown experiment type (1)
ChIP-chip by tiling array (1)
Human - High-throughput sequencing (1)
High-throughput sequencing (1)
Animal - High-throughput sequencing (1)
Spatial transcriptomics by high-throughput sequencing (1)
Bisulfite-seq (1)
ATAC-seq (1)
MicroRNA profiling by array (1)
Proteomic profiling by array (1)
RNA-seq of total RNA (1)

Release Date

2024 (1126)
2025 (818)
2023 (807)
2022 (802)
2021 (718)
2020 (613)
2019 (436)
2018 (296)
2016 (295)
2017 (280)
2015 (223)
2014 (146)
2026 (133)
2013 (88)
2012 (76)
2011 (54)
2010 (45)
2009 (15)
2008 (15)
2007 (7)
2005 (3)
2006 (2)
2004 (1)

Lab affiliation

Amsterdam UMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, Netherlands (7)
Centre for Cancer Cell & Molecular Biology, Barts Cancer Institute, Queen Mary University of London, Charterhouse Square, London EC1M 6BQ, UK. (5)
Lineberger Comprehensive Cancer Center at UNC Chapel Hill (4)
Cold Spring Harbor Laboratory (3)
Daglig leder, PROMEC Institutt for klinisk og molekylær medisin lars.hagen@ntnu.no 73598508 72573342 Laboratoriesenteret, 231.04.008, Øya, Erling Skjalgssons gate 1 (3)
Department of Biochemistry and Molecular Biology and the Biomedicine Discovery Institute; Monash University; Clayton 3800; Victoria; Australia (3)
University of Manchester (3)
CRUK -CRUK Scotland nstitute for Cancer Research - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (2)
Cancer Research UK Manchester Institute (2)
Centre for Cancer Cell & Molecular Biology Barts Cancer Institute Queen Mary University of London Charterhouse Square London EC1M 6BQ U.K. (2)
Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center (2)
Faculty of Biology, Medicine & Health, Manchester Cell-Matrix Centre, Manchester Academic Health Science Centre, University of Manchester, Michael Smith Building, Oxford Road, Manchester, M13 9PT, United Kingdom (2)
General Manager of PROMEC Department of Clinical and Molecular Medicine +4773598508 +4772573342 Laboratoriesenteret, 231.04.008, Øya, Erling Skjalgssons gate 1 Norway (2)
Head of Laboratory of Neuro-Oncology, Neurology, Clinical & Cancer Proteomics (2)
Johns Hopkins University (2)
Personalized Genomic Medicine Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB) (2)
Professor and Vice Chairman for Research Department of Biochemistry and Molecular Genetics Co-Leader, Experimental Therapeutics Program UAB O'Neal Comprehensive Cancer Center Hugh Kaul Human Genetics Building, Kaul 504A The University of Alabama at Birmingham Birmingham, Alabama (2)
Tianjin Medical University Cancer Institute and Hospital (2)
1 Department of Hepatobiliary & Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071, PR China. 2 Clinical Medicine Research Center for Minimally Invasive Procedure of Hepatobiliary & Pancreatic Diseases of Hubei Province, Hubei, PR China. 3 Taikang Center for Life and Medical Sciences of Wuhan University (1)
1. Garvan Institute of Medical Research, Cancer Ecosystems Program, and The Kinghorn Cancer Centre, Darlinghurst, Sydney, New South Wales, Australia. 2. School of Clinical Medicine, Faculty of Medicine and Health, University of New South Wales (UNSW), Kensington, Sydney, New South Wales, Australia. (1)
1Department of Hepatobiliary & Pancreatic Surgery, Zhongnan Hospital of Wuhan University, Wuhan, 430071, PR China. 2Clinical Medicine Research Center for Minimally Invasive Procedure of Hepatobiliary & Pancreatic Diseases of Hubei Province, Hubei, PR China. 3Taikang Center for Life and Medical Sciences of Wuhan University (1)
1¬ MRM Proteomics Inc, Montreal, Quebec, Canada 2 Segal Cancer Proteomics Centre, Lady Davis Institute, Jewish General Hospital, McGill University, Montreal, Quebec, Canada 3 Gerald Bronfman Department of Oncology, Jewish General Hospital, McGill University, Montreal, Quebec, Canada (1)
Acting Head of Proteomics (1)
Affiliated Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology (1)
AmsterdamUMC, Vrije Universiteit Amsterdam, Medical Oncology, Cancer Center Amsterdam, OncoProteomics Laboratory, Amsterdam, The Netherlands (1)
Assistant Professor of Biological Sciences Augusta University C2014 Science Hall 2500 Walton Way, Augusta-GA (1)
Associate Professor Tracy Putoczki The Walter and Eliza Hall Institute of Medical Research Australia (1)
Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS) School of Life Sciences Technical University Munich (TUM) Gregor-Mendel-Straße 4 85354 Freising GERMANY Bavarian Center for Biomolecular Mass Spectrometry Technische Universität München Gregor-Mendel-Straße 4 85354 Freising DEUTSCHLAND / GERMANY (1)
Bavarian Center for Biomolecular Mass Spectrometry (BayBioMS) Technical University Munich (TUM) Gregor-Mendel-Straße 4 85354 Freising GERMANY (1)
Bertis Inc. (1)

Location

United States (32)
France (11)
Spain (10)
Italy (7)
United Kingdom (7)
Belgium (6)
Germany (6)
Australia (5)
Canada (4)
Netherlands (4)
South Korea (4)
Japan (3)
Taiwan (3)
China (2)
Denmark (2)
Israel (2)
Singapore (2)
Asia except Japan (1)
Austria (1)
Brazil (1)
Chile (1)
Czechia (1)
Estonia (1)
Europe (1)
Finland (1)
Georgia (1)
Ireland (1)
Latvia (1)
Lithuania (1)
Malaysia (1)

Keyword

CRC (9)
PDAC (8)
KRAS (7)
Pembrolizumab (6)
Immunotherapy (4)
Carboplatin (3)
Gastrointestinal Neoplasms (3)
Gemcitabine (3)
HNSCC (3)
NRAS (3)
PD-1 (3)
Paclitaxel (3)
Pemetrexed (3)
Phase 1 (3)
Adjuvant therapy (2)
Albumin-Bound Paclitaxel (2)
BRAF (2)
Bevacizumab (2)
Carcinoma, Pancreatic Ductal (2)
Cell therapy (2)
Circulating tumor DNA (ctDNA) (2)
Colorectal cancer (CRC) (2)
Cyclophosphamide (2)
Intestinal Neoplasms (2)
Kirsten rat sarcoma (KRAS) (2)
Metastatic Cancer (2)
Metastatic cancer (2)
Neuroblastoma ras viral oncogene homolog (NRAS) (2)
PD-L1 (2)
Pancreas (2)

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Metabolome profiling on resectable pancreatic ductal adenocarcinoma patients with early liver metastasis

Pancreatic ductal adenocarcinoma (PDAC) remains difficult to cure because many patients develop liver metastasis even after apparently curative resection. Bile is in close contact with the pancreatobiliary system, but its multi-omic features in resectable PDAC and their relationship to postoperative...

2026-10-17 | MTBLS15948 | MetaboLights

Mutations-Upstream-of-Metabolomic-Signature Based Functional Analyses Identify Prognostic Biomarkers and Therapeutic Targets in Pancreatic Ductal Adenocarcinoma

Cross-talk among downstream regulatory networks of genome mutations has been the major hypothetical mechanism underlying poor prognosis and low-responsive rates for targeted therapy of pancreatic ductal adenocarcinoma (PDAC). By applying a causal inference-based mutation-upstream-of-the-metabolom...

2025-10-13 | MTBLS13111 | MetaboLights

Mutations-Upstream-of-Metabolomic-Signature Based Functional Analyses Identify Prognostic Biomarkers and Therapeutic Targets in Pancreatic Ductal Adenocarcinoma

2025-10-13 | MTBLS13116 | MetaboLights

Mutations-Upstream-of-Metabolomic-Signature Based Functional Analyses Identify Prognostic Biomarkers and Therapeutic Targets in Pancreatic Ductal Adenocarcinoma

2025-10-13 | MTBLS13127 | MetaboLights

Microarray expression profile analysis of circular RNAs in human pancreatic ductal adenocarcinoma

To explore the potential involvement of circular RNAs (circRNAs) in pancreatic ductal adenocarcinoma (PDAC) oncogenesis, we conducted circRNA profiling in six pairs of human PDAC and adjacent normal tissue by microarray. Our results showed that clusters of circRNAs were aberrantly expressed in PDAC ...

ORGANISM(S): Homo sapiens

2015-11-20 | E-GEOD-69362 | biostudies-arrayexpress

ELAPOR1 induces the classical/progenitor subtype and contributes to reduced disease aggressiveness through metabolic reprogramming in pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is a heterogeneous disease with distinct molecular subtypes described as classical/progenitor and basal-like/squamous PDAC. We hypothesized that integrative transcriptome and metabolome approaches can identify candidate genes whose inactivation contributes to ...

2024-04-02 | MTBLS9418 | MetaboLights

KSN01_Proteome_CellLine: Aberrant (pro)renin receptor expression induces genomic instability in pancreatic ductal adenocarcinoma through upregulation of SMARCA5/SNF2H

Aberrant (pro)renin receptor expression induces genomic instability in pancreatic ductal adenocarcinoma through upregulation of SMARCA5/SNF2H

ORGANISM(S): Homo Sapiens (human)

2020-12-15 | PXD010107 | JPOST Repository

Transcriptional profiling by array of pancreatic ductal adenocarcinoma xenograft models

We generated novel patient derived xenograft (PDX) and cell line -derived xenograft models for pancreatic ductal adenocarcinoma (PDAC) which reflect different molecular subtypes. Pancreatic ductal adenocarcinoma is currently the tumor with the fourth highest mortality rate. Recently, subtypes of PDA...

ORGANISM(S): Homo sapiens

2016-01-12 | E-MTAB-4029 | biostudies-arrayexpress

Low-Protein Diet Enhances Anti-Tumor Immunity in Pancreatic Cancer through Microbiota-Derived Uridine Diphosphate-Galactose

Low-protein diets (LPD) have been linked to improved metabolic health, but their role in pancreatic ductal adenocarcinoma (PDAC) immunotherapy remains unclear. Here we show that an LPD suppresses PDAC progression in male mice by remodeling the gut microbiota and activating anti-tumor immunity. LPD p...

2026-07-09 | MTBLS14989 | MetaboLights

Whole-Tissue Gene Expression Study of Pancreatic Ductal Adenocarcinoma

Expression analysis of 36 pancreatic ductal adenocarcinoma tumors and matching normal pancreatic tissue samples from pancreatic cancer patients of the Clinical Institute Fundeni (ICF) using Affymetrix U133 Plus 2.0 whole-genome chips. Pairs of normal and tumor tissue samples were obtained at the tim...

ORGANISM(S): Homo sapiens

2009-06-13 | E-GEOD-15471 | biostudies-arrayexpress

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