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TranscriptomicsTranscription profiling of thymotyctes from parp-2 -/- mice to determine whether dis-regulation of a genetic pathway could explain the increased apoptosis of these cells
In order to determine whether dis-regulation of a genetic pathway could explain the increased apoptosis of parp-2-/- double positive thymocytes, the gene expression profiles in double positive thymocytes derived from wild-type and parp-2-/- mice were analysed using Affymetrix oligonucleotide chips (...
ORGANISM(S): Mus musculus 
2007-05-23 | E-MEXP-755 | biostudies-arrayexpress
MetabolomicsMetabolic analysis of Parp1 ko/wt Saline & Bleo Mouse Lung Fiboblasts and Human IPF & Normal Lung Fiboblasts (Part 2)
Not available
ORGANISM(S): Mus musculus 
ST000275 | MetabolomicsWorkbench
TranscriptomicsDepletion of PARP-2 in HepG2 cells
Poly(ADP-ribose) polymerase-2 (PARP-2) is acknowledged as a DNA repair enzyme; however, recently metabolic properties had been attributed to it. Hereby, we examined the metabolic consequences of PARP-2 ablation in liver. Microarray analysis of PARP-2 knockdown HepG2 cells revealed the dysregulation ...
ORGANISM(S): Homo sapiens 
2013-12-31 | E-GEOD-43981 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression profiles between Parp-2-/- and wild-type hematopoietic stem/progenitors cell at basal and in response to 5 Gy gamma Irradiation (2.5 hours post-irradiation)
Gene expression profile between Parp-2-/- and wild-type hematopoietic stem/progenitor cells at basal and to the early response (2.5 hours) to 5 Gy total body irradiation We analyzed 2 arrays from each condition. Each samples represent a pool of at least 3 mice
ORGANISM(S): Mus musculus 
2013-08-06 | E-GEOD-42022 | biostudies-arrayexpress
GenomicsDepletion of PARP-2 in C2C12 cells
Depletion of PARP-2 in C2C12 cells
PRJNA428451 | ENA
GenomicsPARP-1/PARP-2 double deficiency results in recurrent early pregnancy loss and decidualization failure in mice
PARP-1/PARP-2 double deficiency results in recurrent early pregnancy loss and decidualization failure in mice
PRJNA716989 | ENA
GenomicsDistinct roles of PARP-1 and PARP-2 in c-Myc-driven B cell Lymphoma in mice
Distinct roles of PARP-1 and PARP-2 in c-Myc-driven B cell Lymphoma in mice
PRJNA602629 | ENA
TranscriptomicsDepletion of PARP-2 in HepG2 cells
Poly(ADP-ribose) polymerase-2 (PARP-2) is acknowledged as a DNA repair enzyme; however, recently metabolic properties had been attributed to it. Hereby, we examined the metabolic consequences of PARP-2 ablation in liver. Microarray analysis of PARP-2 knockdown HepG2 cells revealed the dysregulation ...
ORGANISM(S): Homo sapiens 
2013-12-31 | GSE43981 | GEO
TranscriptomicsDepletion of PARP-2 in C2C12 cells
Poly(ADP-ribose) polymerase-2 (PARP-2) is acknowledged as a DNA repair enzyme; however, recently metabolic properties had been attributed to it. Hereby, we examined the metabolic consequences of PARP-2 ablation in skeletal muscle.
ORGANISM(S): Mus musculus 
2020-12-18 | GSE108737 | GEO
TranscriptomicsPARP-1/PARP-2 double deficiency results in recurrent early pregnancy loss and decidualization failure in mice
Specifically, we found inhibition of PARP-1 and PARP-2 catalytic activity, or tissue-specific genetic knockout, results in a severe fertility defect. Transcriptomic analyis uncovered that PARP-1;PARP-2-deficient mice have defects in the progression of stromal cell decidualization manifesting in preg...
ORGANISM(S): Mus musculus 
2021-09-13 | GSE169544 | GEO
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