patient fibroblasts

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Unknown (3313)
Transcriptomics (1157)
Genomics (1035)
Proteomics (182)
Other (40)
Methylation profiling (21)
Metabolomics (12)
Genomic (3)
Clinical (1)

Organisms

Homo sapiens (1149)
Mus musculus (189)
Aerococcus urinae NBRC 15544 = CCUG 36881 (128)
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Apostichopus japonicus (128)
Canis lupus familiaris (128)
Carya cathayensis (128)
Clostridioides difficile 630 (128)
Cyanophora paradoxa (128)
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Histomonas meleagridis (128)
Human immunodeficiency virus 1 (128)
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Drosophila melanogaster (4)
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synthetic construct (3)
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Candida albicans (1)
Saccharomyces cerevisiae (1)

Organisms

Homo sapiens (714)
Mus musculus (90)
Drosophila melanogaster (3)
Sus scrofa (2)
Escherichia coli DH5[alpha] (1)
Danio rerio (1)
Rattus norvegicus (1)
Saccharomyces cerevisiae (1)
synthetic construct (1)

Repository

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geo (565)
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ExpressionAtlas (1)
GNPS (1)
MetabolomicsWorkbench (1)

Tissue

Fibroblast (62)
Cell culture (52)
Skin (11)
Epithelial cell (9)
Lung (5)
Pleural mesothelium (5)
Embryonic stem cell (4)
Fibroblast of lung (3)
Heart (3)
Mesothelial fibroblast (3)
Primary cell (3)
Skin fibroblast (3)
Blood cell (2)
Breast cancer cell (2)
Liver (2)
Mesothelial cell of pleura (2)
Pancreas (2)
Permanent cell line cell (2)
Fibroblast cells (1)
Blood (1)
Blood plasma (1)
Brain (1)
Cell suspension culture (1)
Colon (1)
Colorectal cancer cell (1)
Connective tissue (1)
Duct of salivary gland (1)
Embryo (1)
Epithelium (1)
Fascia (1)

Disease

Normal (9)
Breast cancer (6)
Rheumatoid arthritis (4)
Not Available (3)
Cardiovascular system disease (3)
Colorectal cancer (3)
Malignant pleural mesothelioma (3)
Congenital disorder of glycosylation (2)
Malignant neoplasm of ovary (2)
Mitochondrial metabolism disease (2)
Adams-Oliver syndrome (1)
Myelodysplasia (1)
Idiopathic pulmonary fibrosis (1)
Gastric carcinoma (1)
Acute erythroid leukemia (1)
Perilobar nephrogenic rest (1)
Sanfilippo syndrome type B (1)
Apert syndrome (1)
Mitochondrial complex I deficiency (1)
Hutchinson Gilford Progeria Syndrome (1)
Pancreatic ductal adenocarcinoma (1)
Hutchinson-Gilford Progeria Syndrome (1)
Tumour (1)
Short stature-onychodysplasia-facial dysmorphism-hypotrichosis syndrome (1)
Cancer (1)
Glioblastoma (1)
Adenocarcinoma (1)
Control (1)
Carcinoma (1)
Mitochondrial disease (1)

Technology Type

Mass Spectrometry (129)
Shotgun proteomics (72)
Bottom-up proteomics (20)
Gel-based experiment (14)
Affinity purification coupled with mass spectrometry proteomics (11)
Data-dependent acquisition (11)
Data-independent acquisition (6)
Mass spectrometry (5)
Mass spectrometry assay (3)
SWATH MS (3)
Top-down proteomics (3)
NMR spectroscopy (2)
All-ion fragmentation (2)
HDMSE (2)
ILLUMINA, Illumina HiSeq 2500 (1)
Illumina HiSeq 2000, ILLUMINA, Illumina HiSeq 2500 (1)
ESI (1)
DiaPASEF (1)
MSE (1)
Mass spectrometry imaging (1)
SRM/MRM (1)

Instrument Platform

Illumina NovaSeq 6000 (29)
NextSeq 500 (22)
Illumina HiSeq 2500 (13)
Illumina HiSeq 4000 (10)
Illumina HiSeq 2000 (6)
NextSeq 2000 (4)
NextSeq 550 (3)
Illumina NovaSeq X (2)
NA (2)
DNBSEQ-G400 (2)
Illumina HiSeq 1500 (2)
Advanced Sequencing Facility (1)
Epidermal cells : Trypsin dissociation / Dermal cells :MACS Whole Skin Dissociation Kit (1)
Bio-Rad CFX96 Real-time System (1)
BD LSRFortessa (1)
10x Chromium (1)
GeneChip Fluidics Station 450, GeneChip Scanner 3000 (1)
NanoDrop ND-1000, Bioanalyzer (1)
Qubit instrument, DNA HS kit (1)
High Sensitivity DNA kit (1)
BioRad SureCell (1)
Agilent SureScan High Resolution scanner (1)
Illumina Hiseq 2500 (1)
DNA Microarray Scanner (Model G2505C, Agilent Technologies) (1)
Agilent Microarray Scanner G2505c (1)
BDRhapsody (1)
IScan Illumina (1)
GeneChip 3000 7G scanner (1)
Unspecified (1)
G2505A DNA microarray scanner [Agilent] (1)

Publication Date

2026 (123)
2025 (109)
2023 (109)
2013 (107)
2015 (104)
2014 (102)
2024 (98)
2012 (89)
2022 (79)
2010 (74)
2016 (72)
2021 (67)
2011 (67)
2020 (65)
2019 (44)
2018 (43)
2009 (33)
2008 (27)
2017 (24)
2007 (16)
2005 (8)
2004 (1)
2003 (1)
2027 (1)

CHEBI ID

CHEBI:18132 (3)
CHEBI:17562 (3)
CHEBI:16870 (3)
CHEBI:17268 (3)
CHEBI:16704 (3)
CHEBI:18012 (3)
CHEBI:15354 (3)
CHEBI:17596 (3)
CHEBI:17368 (3)
CHEBI:16113 (2)
CHEBI:44215 (2)
CHEBI:15611 (2)
CHEBI:25094 (2)
CHEBI:18237 (2)
CHEBI:15356 (2)
CHEBI:22660 (2)
CHEBI:16797 (2)
CHEBI:18186 (2)
CHEBI:17234 (2)
CHEBI:16977 (2)
CHEBI:24898 (2)
CHEBI:25017 (2)
CHEBI:15428 (2)
CHEBI:17754 (2)
CHEBI:15741 (2)
CHEBI:17821 (2)
CHEBI:17154 (2)
CHEBI:17568 (2)
CHEBI:27266 (2)
CHEBI:18050 (2)

Metabolite Name

Choline (5)
Valine (3)
Arginine (3)
Guanine (3)
Cytosine (3)
Uridine (3)
Creatinine (3)
Creatine (3)
Hypoxanthine (3)
N,N-Dimethylformamide (2)
Trimethylamine (2)
Cabergoline (2)
Acetate (2)
Histidine (2)
Aspartate (2)
NAD+ (2)
AMP (2)
Uracil (2)
Betaine (2)
Thymine (2)
Thiamine (2)
Niacinamide (2)
Diethanolamine (2)
Glutathione (2)
L-Proline (2)
7-Methylguanine (2)
Chenodeoxycholate (2)
ADP (2)
NAD (2)
Kynurenine (2)

First Public Date

2026 (140)
2025 (120)
2023 (115)
2024 (107)
2014 (95)
2021 (64)
2022 (62)
2020 (53)
2019 (41)
2016 (30)
2018 (28)
2015 (27)
2017 (19)
2013 (9)

Classification

bacteria (1)

Modification

4-tetrahydrothiazine-3-carboxylic acid (1)

Study status

Recruiting (1)

Study type

Transcription profiling by array (476)
RNA-seq of coding RNA (84)
RNA-seq of coding RNA from single cells (28)
Methylation profiling by array (24)
Comparative genomic hybridization by array (20)
Unknown experiment type (13)
ChIP-seq (9)
Genotyping by array (8)
Transcription profiling by RT-PCR (8)
Other (8)
Human - High-throughput sequencing (6)
RNA-seq of non coding RNA (4)
ChIP-chip by tiling array (3)
DNA-seq (3)
Methylation profiling by high throughput sequencing (3)
Human - Single-cell sequencing (2)
Cell line - High-throughput sequencing (2)
MicroRNA profiling by high throughput sequencing (2)
RNA-seq of total RNA (2)
Cell line - Methylation microarray (1)
Human - Two-color microarray (1)
Cell line - One-color microarray (1)
Human - One-color microarray (1)
Transcription profiling by tiling array (1)
ChIP-chip by array (1)
Single nucleus RNA sequencing (1)
Genotyping by high throughput sequencing (1)
Observational (1)

Release Date

2025 (413)
2023 (369)
2022 (342)
2024 (340)
2021 (316)
2019 (251)
2020 (247)
2016 (213)
2018 (209)
2015 (208)
2017 (199)
2014 (173)
2013 (157)
2012 (132)
2010 (106)
2011 (101)
2009 (56)
2026 (50)
2008 (43)
2007 (33)
2005 (13)
2006 (13)
2001 (10)
2000 (7)
2004 (6)
2002 (6)
2003 (5)
1999 (4)
1998 (2)

Lab affiliation

University of Vienna, Faculty of Chemistry, Department of Analytical Chemistry (5)
Associate Professor Department of Biochemistry Room 220, Research and Innovation Centre, University of Regina, Regina, Saskatchewan S4S 0A2 (4)
Bioanalytics, Leibnizinstitut für analytische Wissenschaften-ISAS-e.V., Germany (2)
Centre for Genomic Regulation (CRG) (2)
Department of Laboratory Medicine and Pathology Mayo Clinic, Rochester, Minnesota 55905 United States (2)
Head of Proteomics (2)
(1) Wellcome Centre for Mitochondrial Research, Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, UK; (2) Leibniz-Institute für Analytische Wissenschaften-ISAS- e.V., Dortmund, Germany (1)
1. Leibniz-Institut für Analytische Wissenschaften - ISAS - e.V., Dortmund, Germany 2. Pediatric Neurology, University Hospital Essen, University of Duisburg-Essen, Faculty of Medicine, Essen, Germany (1)
1.School of Life and Environmental Sciences, Faculty of Science, Engineering and Built Environment, Deakin University, Geelong 3216, Australia 2.Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, 3168 Melbourne, Australia 3.Department of Molecular and Translational Science, Monash University, 3168 Melbourne, Australia (1)
1Department of Biochemistry and Pharmacology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC, 3010, Australia 2Murdoch Children’s Research Institute, Melbourne, VIC 3052, Australia 3Victorian Clinical Genetics Services, Murdoch Children’s Research Institute, Melbourne, VIC, 3052, Australia (1)
Akhilesh Pandey, M.D., Ph.D. Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota 55905, United States (1)
CCB, LUMC, Netherlands (1)
CNRS-IPHC-LSMBO (1)
CRUK - Beatson Institute for Cancer Research - Switchback Rd, Bearsden, Glasgow G61 1BD - United Kingdom (1)
Cambridge Institute for Medical Research, University of Cambridge (1)
Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver V5Z 1L3, Canada. (1)
Cell Biology and Physiology, The University of North Carolina at Chapel Hill (1)
Cell and Chemical Biology LUMC The Netherlands (1)
Cell and Chemical Biology Leiden University Medical Center Leiden, The Netherlands (1)
Cellzome (1)
Centre for Inherited Metabolic Diseases, Karolinska University Hospital, 171 76 Stockholm, Sweden Department of Medical Biochemistry and Biophysics, Karolinska Institutet, 171 65 Stockholm, Sweden (1)
Charité – Universitätsmedizin Berlin, Institute of Medical Genetics and Human Genetics, 13353 Berlin, Germany. (1)
Chemical & Biomolecular Engineering, Johns Hopkins University (1)
Cologne Center for Genomics (CCG), University of Cologne, Faculty of Medicine and University Hospital Cologne (1)
Complex Carbohydrate Research Center, Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA. (1)
Comprehensive Pneumology Center (CPC), University Hospital, Ludwig-Maximilians University, Helmholtz Zentrum München, Munich, Member of the German Center for Lung Research (DZL), Germany (1)
Comprehensive Pneumology Center (CPC), University Hospital, Ludwig-Maximilians University, Helmholtz Zentrum München, Munich, Member of the German Center for Lung Research (DZL), Germany. (1)
Department Of Pharmacy (1)
Department of Bioanalytics, Leibniz-Institut für Analytische Wissenschaften ISAS e.V., Dortmund, Germany. (1)
Department of Biochemistry & Pharmacology, Bio21 Institute, University of Melbourne (1)

Location

France (1)

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Metabolomics of patient-derived fibroblasts

Not available

ORGANISM(S): Homo sapiens

ST001441 | MetabolomicsWorkbench

Selective galactose culture condition reveals distinct metabolic signatures in pyruvate dehydrogenase and complex I deficient human skin fibroblasts

INTRODUCTION: A decline in mitochondrial function represents a key factor of a large number of inborn errors of metabolism, which lead to an extremely heterogeneous group of disorders.

OBJECTIVES: To gain insight into the biochemical consequences of mitocho...

2021-10-06 | MTBLS761 | MetaboLights

Proteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - primary mammary fibroblasts treated with IL1-beta

Breast cancer is still the most common type of cancer in women; an important role in carcinogenesis is actually attributed to cancer-associated fibroblasts. In this study we investigated whether it is possible to assess the functional state of cancer-associated fibroblasts through tumor tissue prote...

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-20 | MSV000079966 | MassIVE

Proteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - primary mammary fibroblasts treated with TGF-beta

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-20 | MSV000079968 | MassIVE

Proteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - primary mammary fibroblasts

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-20 | MSV000079940 | MassIVE

Transcriptional profiling by array of human head and neck squamous cell carcinoma to study the correlation between galectin-1 upregulation and the presence of SMA positive cancer-associated fibroblasts

In this study, we set the presence of smooth muscle actin (SMA)-positive cancer-associated fibroblasts (CAFs) in relation to galectin-1 and its in vivo competitor (galectin-3). In squamous cell carcinomas of head and neck, upregulation of galectin-1 presence is highly significantly correlated to pre...

ORGANISM(S): Homo sapiens

2012-11-01 | E-MTAB-850 | biostudies-arrayexpress

Proteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - tumor-distant tissue sections

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-20 | MSV000079950 | MassIVE

Proteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - ZR-75-1 breast cancer cells

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-20 | MSV000079958 | MassIVE

Proteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - bulk tumor tissue

ORGANISM(S): Homo Sapiens (ncbitaxon:9606)

2016-07-20 | MSV000079947 | MassIVE

Proteome profiling of breast cancer biopsies reveals a wound healing signature of cancer-associated fibroblasts - tumor-near tissue sections