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UnknownFlap Dynamics in Pepsin-Like Aspartic Proteases: A Computational Perspective Using Plasmepsin-II and BACE-1 as Model Systems.
Not available
S-EPMC8889585 | biostudies-literature
UnknownAnalysis of crystal structures of aspartic proteinases: on the role of amino acid residues adjacent to the catalytic site of pepsin-like enzymes.
Not available
S-EPMC2374050 | biostudies-literature
UnknownPepsin-like aspartic proteases (PAPs) as model systems for combining biomolecular simulation with biophysical experiments.
Not available
S-EPMC8695779 | biostudies-literature
UnknownThe Adaptable Binding Cleft of RmuAP1, a Pepsin-like Peptidase from <i>Rhodotorula mucilaginosa</i>, Enables the Enzyme to Degrade Immunogenic Peptides Derived from Gluten.
Not available
S-EPMC12730222 | biostudies-literature
UnknownActivation mechanism of plasmepsins, pepsin-like aspartic proteases from Plasmodium, follows a unique trans-activation pathway.
Not available
S-EPMC9116133 | biostudies-literature
TranscriptomicsAmprenavir Mitigates Pepsin-Induced Transcriptomic Changes in Normal and Precancerous Esophageal Cells
Background: Gastroesophageal reflux disease (GERD) is a chronic condition linked to inflammatory and cancerous alterations in esophageal epithelium. Despite the widespread use of acid suppressing proton pump inhibitors (PPIs), the incidence of esophageal adenocarcinoma (EAC) keeps increasing, unders...
ORGANISM(S): Homo sapiens 
2025-02-07 | GSE288541 | GEO
ProteomicsRecombinant shewasin D and shewasin A specificity preferences profiled by proteomic identification of protease cleavage sites (PICS)
We determined the specificity preferences of both recombinant shewasin D and shewasin A (pepsin-like aspartic proteases from S. denitrificans and S. amazonensis, respectively) using proteome-derived peptide libraries and observed remarkable similarities between both shewasins and eukaryotic pepsins,...
ORGANISM(S): Homo sapiens (Human) 
2016-04-05 | PXD003078 | Pride
Pics  trypsin  gluc  shewasin d  shewasin a  shewanella denitrificans  shewanella amazonensis  pepsin-like  specificity profile 
GenomicsAmprenavir Mitigates Pepsin-Induced Transcriptomic Changes in Normal and Precancerous Esophageal Cells
Amprenavir Mitigates Pepsin-Induced Transcriptomic Changes in Normal and Precancerous Esophageal Cells
PRJNA1218264 | ENA
UnknownResidues of acidic chitinase cause chitinolytic activity degrading chitosan in porcine pepsin preparations.
Not available
S-EPMC6821832 | biostudies-literature
UnknownEnzymatic properties, evidence for in vivo expression, and intracellular localization of shewasin D, the pepsin homolog from Shewanella denitrificans.
Not available
S-EPMC4814920 | biostudies-literature
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