Sort   by:  
 Page size 
TranscriptomicsPeriostin
We compared transcriptional differences between Periostin siRNA treated and GFP-siRNA treated in OP9 cells using Affymetrix mouse 430_2 array.
ORGANISM(S): Mus musculus 
2012-01-26 | E-MTAB-519 | biostudies-arrayexpress
TranscriptomicsPeriostin, a cell adhesion molecule, facilitates invasion in the tumor microenvironment and annotates a novel tumor invasive signature in esophageal cancer
Human squamous cell cancers are the most common epithelially derived malignancies. One example is esophageal squamous cell carcinoma (ESCC), which is associated with a high mortality rate that is related to a propensity for invasion and metastasis. We report that periostin, a highly expressed cell a...
ORGANISM(S): Homo sapiens 
2010-07-08 | E-GEOD-21293 | biostudies-arrayexpress
TranscriptomicsThe immunomodulatory effects of periostin on monocyte-derived macrophages
To explore the effects of periostin on tumor-associated macrophagess, we first sorted CD14+ monocytes from peripheral blood mononuclear cells of healthy donors using magnetic-activated cell sorting and then induced their differentiation into macrophages by culture with M-CSF for 5 days. In the absen...
ORGANISM(S): Homo sapiens 
2015-07-14 | E-GEOD-70821 | biostudies-arrayexpress
ProteomicsMapping the Periostin splice isoforms in atopic dermatitis and an in vitro asthma model – A multi-platform analysis using mass spectrometry and RT-qPCR
Periostin is a matricellular protein known to be alternatively spliced to produce isoforms with a molecular weight of 78-91 kDa. In the extracellular matrix, periostin attach to cell surfaces and induce signaling via integrin-binding and participates in fibrillogenesis to organize collagen in the ex...
ORGANISM(S): Homo sapiens (Human) 
2024-07-08 | PXD045287 | Pride
Alternative splicing Prm Periostin Atopic dermatitis Extracellular matrix 
ProteomicsThe C-terminal domain of periostin is intrinsically disordered and interacts with 143 proteins in an in vitro epidermal model of atopic dermatitis
Human periostin is a 78-91 kDa alternatively spliced protein belonging to the group of matricellular proteins. The protein has been implicated in extracellular matrix remodeling, tumor development, and metastasis, inflammatory diseases like atopic dermatitis, psoriasis, and asthma. The C-terminal ma...
ORGANISM(S): Homo sapiens (Human) 
2023-09-15 | PXD040164 | Pride
Heparin-binding protein Extracellular matrix protein Periostin Wound healing Connective tissue Protein‐protein interactions Alternative splicing Intrinsically disordered protein Atopic dermatitis 
ProteomicsPeriostin is a disulfide bonded homodimer and forms a complex with fibronectin in human skin
The protein periostin is a matricellular protein that is expressed in connective tissue. It is composed of five globular domains arranged in an elongated structure with an extensive disordered C-terminal tail. Periostin contains eleven cysteine residues, of which one is unpaired, and the rest forms ...
ORGANISM(S): Homo sapiens (Human) 
2025-01-22 | PXD045285 | Pride
Wound healing Periostin Fibronectin Extracellular matrix 
TranscriptomicsPeriostin cooperates with mutant p53 to mediate invasion
Periostin, a matricellular protein, has been reported to be important in supporting tumor cell dissemination. However, the molecular mechanisms underlying periostin function within the tumor microenvironment are poorly understood. In this study, we observe that loss of periostin decreases esophageal...
ORGANISM(S): Homo sapiens 
2016-06-01 | E-GEOD-48999 | biostudies-arrayexpress
GenomicsPeriostin promotes cell cycle in lung fibroblasts
Periostin promotes cell cycle in lung fibroblasts
PRJNA549462 | ENA
TranscriptomicsPeriosteum contains skeletal stem cells with high bone regenerative potential controlled by Periostin
Bone regeneration relies on the activation of skeletal stem cells (SSCs) that still remain poorly characterized. Here, we show that periosteum contains SSCs with high bone regenerative potential compared to bone marrow stromal cells/skeletal stem cells (BMSCs) in mice. Although periosteal cells (PCs...
ORGANISM(S): Mus musculus 
2018-10-18 | E-MTAB-6417 | biostudies-arrayexpress
GenomicsPeriostin-treated healthy human airway epithelial cell cultures
Periostin-treated healthy human airway epithelial cell cultures
PRJNA1170955 | ENA
Sort   by:  
 Page size