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UnknownPFKFB2-Driven Glycolysis Promotes Dendritic Cell Maturation and Exacerbates Acute Lung Injury.
Not available
S-EPMC12499423 | biostudies-literature
UnknownMechanistic studies of PFKFB2 reveal a novel inhibitor of its kinase activity.
Not available
S-EPMC12097583 | biostudies-literature
UnknownPFKFB2 Promoter Hypomethylation as Recurrence Predictive Marker in Well-Differentiated Thyroid Carcinomas.
Not available
S-EPMC6471408 | biostudies-literature
UnknownA cis-eQTL in PFKFB2 is associated with diabetic nephropathy, adiposity and insulin secretion in American Indians.
Not available
S-EPMC4416128 | biostudies-literature
TranscriptomicsTranscription profiling of non-leukemic individuals before and during in-vivo glucocorticoid treatment
Article title: Expression, regulation and function of phosphofructo-kinase/fructose-biphosphatases (PFKFBs) in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia cells. Glucocorticoids (GCs) cause apoptosis and cell cycle arrest in lymphoid cells and constitute a central component in ...
ORGANISM(S): Homo sapiens 
2011-02-01 | E-GEOD-22779 | biostudies-arrayexpress
UnknownmiR-21-5p inhibits the growth of brain glioma cells through regulating the glycolysis mediated by PFKFB2.
Not available
S-EPMC10590297 | biostudies-literature
TranscriptomicsTranscription profiling of glucocorticoid resistant and sensitive acute lymphoblastic leukemia cell lines
Gene expression data of glucocorticoid resistant and sensitive acute lymphoblastic leukemia cell lines for the article: Expression, regulation and function of phosphofructo-kinase/fructose-biphosphatases (PFKFBs) in glucocorticoid-induced apoptosis of acute lymphoblastic leukemia cells Glucocortic...
ORGANISM(S): Homo sapiens 
2011-02-01 | E-GEOD-22152 | biostudies-arrayexpress
ProteomicsBRAF activation by metabolic stress promotes glycolysis and survival, sensitizing NRASQ61 mutated melanomas to targeted therapy.
NRAS-mutated melanoma lacks an approved first-line treatment. Metabolic reprogramming is considered a novel target to control cancer; however, it is mostly unknow how the NRAS oncogene contributes to this cancer hallmark. Here, we show that NRASQ61-mutated melanomas harbor specific metabolic alterat...
ORGANISM(S): Homo sapiens (Human) 
2023-01-09 | PXD028297 | Pride
Melanoma  braf  nras mutation  metabolic stress  pfkfb2 
UnknownMutation of regulatory phosphorylation sites in PFKFB2 does not affect the anti-fibrotic effect of metformin in the kidney.
Not available
S-EPMC9910667 | biostudies-literature
UnknownPFKFB2-mediated glycolysis promotes lactate-driven continual efferocytosis by macrophages.
Not available
S-EPMC10050103 | biostudies-literature
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