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Pmk1, a highly conserved pathogenicity-related mitogen-activated protein kinase (MAPK) in pathogenic fungi, is phosphorylated and activated by MAP2K and acts as a global regulator of fungal infection and invasive growth by modulating downstream targets. However, the hierarchical CcPmk1 regulatory...

2022-07-11 | MTBLS4463 | MetaboLights
Phosphorus is one of the most important macronutrients required for plant growth and development. The importance of phosphorylation modification in regulating phosphate (Pi) homeostasis in plants is emerging. We performed phosphoproteomic profiling to characterize proteins whose degree of phosphoryl...
ORGANISM(S): Oryza sativa (Rice) 
2021-01-13 | PXD012764 | Pride
Global phosphoproteomic screen to identify the first cellular substrates of CDKL5. CDKL5 knock-out U2OS cells and CDKL5 wt U2OS cells were generated for the TMT-based phosphoproteomic. Thi leads to the identification and further validation of several phosphopetides of MAP1S, CEP131 and CDKL5 itself....
ORGANISM(S): Homo sapiens (Human) 
2018-09-24 | PXD009374 | Pride
Phosphoproteomic dysregulation drives tumor proliferation in Cushing’s disease
Integrated transcriptomic, proteomic, phosphoproteomic, and immunopeptidomic profiling of SF3B1-mutant and wild-type CLL
Integrated transcriptomic, proteomic, phosphoproteomic, and immunopeptidomic profiling of SF3B1-mutant and wild-type CLL
Here, we first reported the construction of a phosphoproteomic landscape of 6 tissues, including callus, leaves, roots, shoot meristem (SM), young panicles (YP) and mature panicles (MP), from Nipponbare (Oryza sativa ssp. japonica). By employing a non-gel, quantitative phosphoproteomic approach, a t...
ORGANISM(S): Oryza sativa (Rice) 
2018-04-11 | PXD005241 | Pride
Network-based elucidation of colon cancer drug resistance by phosphoproteomic time-series analysis
Clematis terniflora DC. is used as traditional herb medicine since ancient China. The active substances in C.terniflora have been confirmed to be effective in treating disease like prostatitis. The UV light radiation is a common environmental factor that damage the plants and has an influence on the...
ORGANISM(S): Clematis terniflora (Sweet autumn clematis) 
2023-03-11 | PXD038136 | Pride
Identification of Biomarkers in Myocardial Hypertrophy and Fibrosis via Integrated Transcriptomic and Phosphoproteomic Profiling
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